Objective Investigating the possibility of revascularization about sterilized infectious bone by ectopic transplantation.Methods 60 rabbits were divided into two groups randomly.Experimental group:After established animal model of infected bone,1.5 cm infectious tibias of the successful animal models were cut out and soaked in iodophor 30 min.The stumps of infectious tibias were debrided and fixed with steel plate.The sterilized tibias were transplant and fixed near the ipsilateral medial vastus and rectus femoris muscle.Control group:1.5 cm normal tibias of healthy rabbits were deal with the same methods as experimental group.At 4 weeks,6 weeks and 8 weeks after operation,the bones by ectopic transplantation of two groups were obtained and observed.The areas of ink stained on the bone surrace by ink perfusion.The numbers of microvessel in bone were counted by pathological section.Then those experimental data were processed and statistic analyzed.Results Four weeks after operation:A thin layer connective tissue membranes on the bone surface were found.Some small amount of ink stained areas on the bone surfaces were scattered.For vascular bureaucratic counts of normal bone,the control group,the experimental group,their (mean ± standard deviation) s were (11.10 ±2.26)/field,(10.20 ±2.10)/field,(10.01 ± 1.91)/field,there was no statistically significant (P > 0.05).Six weeks after operation:there were some thick connective tissue membranes on the graft bone surface.Ink stained areas were spread and uneven distribution.Lumen number in the control group [(21.70 ± 1.77)/field] higher than that of the experimental group [(17.60 ± 2.72)/field],the difference was statistically significant (P < 0.05).Eight weeks after operation:Compared with those formers,there were thicker connective tissue membranes and dense deployment of vessels on the graft bone.For vascular bureaucratic counts of the control group,the experimental group,their (mean ± standard deviation) s were (26.40 ± 1.96)/field,(24.60 ± 2.91)/field,no statistically significant difference between the two groups (P > 0.05).Meanwhile,the counts of new vessels in two groups were increased with the prolonging time (P < 0.05).Conclusion The infectious bone of rabbits can be sterilized by soaked in iodophor.The sterilized bone graft into the tis-sue which has known vessels and a abundant blood supply.After 6 or 8 weeks,the revascularization can be completed and rebuilt the blood circulation of graft bones.Those could create the favorable conditions for the infectious bone replantation to repair bone defetcts. Key words: Model, animal ; Tibia ; Infection; Revascularization ; Staphylococcus aureus