Aim: The present study was conducted to study the spectrum of ophthalmic manifestations in blood dyscrasias and toassess the prevalence of ocular manifestations between acute and chronic blood malignancies.Material and Methods: The Present observational study was conducted on a total of 200 patients diagnosed with blooddyscrasias at the Department of Ophthalmology, tertiary care hospital, Bhuj, during the study period of 2 years. Detailedhistory and examination were conducted, and findings were noted. All relevant haematological investigations were alsodone.Results: Out of 200 patients, anemia was the most common diagnosis observed in 70 (35%) cases, followed by sickle cellanemia 54 (27%). Out of 70 patients with anemia, the majority of cases, i.e. 33, had iron deficiency anemia followed by13 and 5 cases with megaloblastic and aplastic anemia, respectively. Retinal Veinous Tortuosity was the most commonfinding in Thalassemia. In contrast, Veinous Fullness and Tortuosity and sub - conjunctival bleeding were the mostcommon finding in patients with leukemia and coagulation disorders, respectively.Conclusion: The ocular changes of blood dyscrasias are not uncommon as is proved by various clinical and pathologicalstudies. These changes in the eye are due to the hemorrhagic effect of the blood disorders or due to the infiltration of theocular tissues by malignant cells. Ophthalmic manifestations are commonly observed in patients with blood dyscrasia.