Differential equations have a remarkable ability to predict the world around us. They are used in a wide variety of disciplines, from biology, economics, physics, chemistry and engineering. The study of existence and uniqueness, periodicity, asymptotic behavior, stability, and methods of analytic and numerical solutions of fractional differential equations have been studied extensively in a large cycle works; Especially, The study of existence and uniqueness of solution of fractional partial differential equations are then proved by mani methods as: the well-known Lax–Milgram theorem, Energy estimate and fixed point theorem... Among them, we only mention here the apriori estimate method (energy inequality method). The current piece of work concentrates on exploring the existence and uniqueness of a solution for a non-linear boundary value problem that has integrable conditions in the case of fractional partial differential equations. For this we split the proof into two sections: linear and non-linear problem; for the associated linear problem, we derive the a priori bound and demonstrate the density of the operator generated by the problem posed; we solve the non-linear problem by introducing a iterative process. The results show the efficiency of energy inequality method in the case of time fractional order differential equations with integrable conditions our results illustrate the existence and uniqueness of the continuous dependence of solution on fractional order. The work of the authors could be considered as a contribution to the development of the functional analysis method. And to conclude we argue that the research carried out in this article could serve as a contribution for possible studies in the field of applied mathematics.
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