As we all know, the underwater acoustic channel is a time-varying, space-changing, and frequency-varying fading channel with limited bandwidth and severe noise interference. This paper studies and analyzes the main factors restricting the transmission of underwater acoustic channels, and establishes an underwater acoustic multipath time-varying fading channel. The channel coding adopts Quasi-Cyslic Low-Density Parity-Check Codes (QC-LDPC), combined with spread spectrum technology and high-order modulation technology, and utilizes Log-likelihood Ratios Belief Propagation (LLR-BP) is decoded, the simulation results show that LDPC codes have stronger error correction capabilities in underwater acoustic spread spectrum communication systems, ensuring that the system can operate reliably under low SNR conditions.