The use of heat pumps is increasing worldwide, and knowledge of their properties is becoming more and more important. Although numerous tests regarding heat pumps have been performed, due to the large number of influencing variables, the entire range of input parameters is not covered, and there is no overall picture regarding the range of the coefficient of performance (COP) of heat pumps and their output parameters. This study extends existing research and provides a much more detailed comparison of results for the application of R1234yf and R1234ze(E) refrigerants, including the pressure drop across the evaporator, condenser, and internal heat exchanger (IHX). The appropriate mathematical model for the selected components was defined and verified experimentally. A total of 60 series of measurements were performed at different evaporating and condensing temperatures. The deviation of the numerical simulation results from the experimentally determined results was up to 7.4% for cooling capacity, 8.1% for heating capacity, 7.2% for COP and 6.8% for compressor energy consumption. This study shows that COP increases from 4.77% to 10.73% for R1234ze(E) compared to R1234yf. The use of an IHX in the thermal cycle further increases COP for both refrigerants between 2.61% and 4.99%.