An experimental investigation was carried out to evaluate the restraint moments generated at interior piers of bridges constructed with full-span prestressed concrete form panels. These moments result from the restraint of time-dependent deformation after adjacent spans are made continuous through a composite cast-in-place concrete topping. The experimentally determined moments from this investigation were compared with values calculated using current design methods for continuous prestressed concrete girders. It was concluded that these design methods, which ignore cracking of the cast-in-place topping, greatly overestimate the negative restraint moments in composite construction with shallow prestressed members. A new method for calculating restraint moments in bridges with shallow prestressed members, which includes provisions for cracking, is presented. Numerical design examples are included to illustrate the proposed method.