Embedded column base has been widely used in concrete-filled steel tube (CFST) structures due to its high rigidity and good seismic performance. However, the strength analysis of the embedded CFST column base was not yet clear since there was little experimental research on it. In this paper, the experimental investigations of six embedded concrete-filled rectangular steel tube (CFRST) column bases under constant axial load and cyclic load were carried out to study the effects of embedded depth, improvement measures and axial compression ratios on the seismic performance of the column bases. The experimental results indicated that setting stiffeners, increasing the embedded depth or axial compression ratios could improve the seismic performance of the column base. In this experiment, the critical embedded depths of the columns with or without stiffeners were 0.7 and 1.5 times the column width B respectively. When the embedded depth was 0.7B, the contribution of anchor bolts to the moment resistance capacity of the column bases could reach up to 14.2%. Based on the analysis of the force transmission mechanism between the column and the concrete foundation in the embedded CFRST column base, a design method considering the contribution of different components to the moment resistance capacity of the CFRST column bases is proposed. The prediction results are in good agreement with the tested results and collected data, within ± 15% error. The parameter analysis based on the design method has revealed the influence patterns of various parameters on the moment resistance capacity of the column bases.