The western region of Jilin province is one of the areas with the most serious saline soil, which is the type of inland soda salt. In order to study the damage law of concrete under the condition of long-term erosion by the soluble salts in saline soil or groundwater or saturated salt water, three groups of salt solution, Na2SO4, NaCl, NaHCO3 solution, were made according to the content of soluble salts in saline soil of Daan city in spring, and water was as a comparison. The comparing tests of long-term immersion were conducted on the normal concrete specimens with the size of 40mm×40mm×160mm. The results show that there is little change on the appearance, mass and dynamic elastic modulus of concrete soaked in water. But for the concrete soaked in salt solution, the loss rate of mass changes from reduction to growth, the relative dynamic elastic modulus of concrete grows at first and declines later. Through analysis of electron microscope scanning, energy spectrum and chemical composition of concrete samples, concrete damage caused by salts includes chemical erosion and salt crystallization damage. Na2SO4 mainly influences the dynamic elastic modulus of concrete, NaCl mainly influences the mass of concrete due to its strong penetration, while NaHCO3, ranking between the two salts above, largely influences not only the mass of concrete, but also the dynamic elastic modulus of concrete.