SMP Concentrations Research Articles

Innovative high-performance and energy-positive Co-treatment of organic kitchen waste and domestic wastewater using a fluidized bed ceramic membrane bioreactor

The aim of the study was to efficiently treat organic kitchen waste (FW) and domestic wastewater (DWW) together in an anaerobic fluidized bed bioreactor equipped with a ceramic membrane (AnFCMBR) through a sustainable approach considering energy recovery. The system operated continuously for 519 days at room temperature, and different filtration fluxes (1.7 and 5 L/m2/h), hydraulic retention times (HRTs) (22 h and 7 h), and organic loading rate (OLRs) (0.46, 1.52, 3.42, 6.08 kg/m3.d) were tested. The amount of organic matter in DWW may be insufficient for feasible gas production, but this challenge can be resolved through the addition of food waste. Influent chemical oxygen demand (COD) of 500 ± 143 mg/L gradually increased to 2000 ± 196 mg/L by increasing the portion of FW. The COD removal ranged from 92 to 98% throughout the study, with the membrane and the cake layer contributing 5–8% to the performance. Average supernatant SMP and EPS concentrations increased from 5 ± 1 to 45 ± 5 mg COD/L and from 54 ± 7 to 254 ± 26 mg COD/g VSS, respectively, when the highest amount of FW was added to the synthetic wastewater. This significant increase in SMP and EPS concentrations due to the addition of FW negatively impacted the filtration performance. SRF and CST values also increased with rising OLR, especially with the supplementation of synthetic wastewater with FW.After FW started to be mixed with DWW, the methane production increased approximately 5.5 times. With the use of AnFCMBR for the co-treatment of FW and DWW, it is possible to achieve energy-positive treatment with high-quality effluent that can be reused for various applications, such as irrigation. The methane produced provided 12 times more energy than was needed to operate the bioreactor.This is the first study evaluating the co-treatment of FW and DWW in AnFCMBR under varying operational parameters.

Microplastic volumes in Tokyo Bay

Microplastic (MP) pollution is a rising environmental concern. This study investigated MP concentrations in Tokyo Bay using neuston net for surface sampling and deep-sea plankton pump for underwater sampling across six stations at multiple depths. Results revealed substantial variation in MP concentrations. Surface large microplastics (LMP, > 350 μm) ranged from 0.21 × 10−3 to 3.34 × 10−3 pieces L−1, averaging 1.26 × 10−3 pieces L−1, while surface small microplastics (SMP, 60 μm to 350 μm) were highest at head of the bay (11.5 ± 3.05 pieces L−1). SMP concentrations varied with depth and position, peaking at center of the bay (5.79 ± 1.63 pieces L−1 at 2 m). Additionally, the total amount of surface LMP was estimated at 10.3 m3 and SMP at 15.0 m3 in the Tokyo Bay. This study provides a comprehensive picture of the spatial and vertical distribution of MP in Tokyo Bay.

Spatial distribution of small microplastics in the Norwegian Coastal Current

High concentrations of microplastic (MP) particles have been reported in the Arctic Ocean. However, studies on the high-resolution lateral and vertical transport of MPs from the European waters to the Arctic are still scarce. Here, we provide information about the concentrations and compositions of MPs in surface, subsurface, and deeper waters (< 1 m, ∼ 4 m, and 17–1679 m) collected at 18 stations on six transects along the Norwegian Coastal Current (NCC) using an improved Neuston Catamaran, the COntinuos MicroPlastic Automatic Sampling System (COMPASS), and in situ pumps, respectively. FTIR microscopy and spectroscopy were applied to measure MP concentration, polymer composition, and size distribution. Results indicate that the concentrations of small microplastics (SMPs, <300 μm) varied considerably (0–1240 MP m−3) within the water column, with significantly higher concentrations in the surface (189 MP m−3) and subsurface (38 MP m−3) waters compared to deeper waters (16 MP m−3). Furthermore, the average concentration of SMPs in surface water samples was four orders of magnitude higher than the abundance of large microplastics (LMPs, >300 μm), and overall, SMPs <50 μm account for >80 % of all detected MPs. However, no statistically significant geographical patterns were observed in SMP concentrations in surface/subsurface seawaters between the six sampling transects, suggesting a relatively homogeneous horizontal distribution of SMPs in the upper ocean within the NCC/Norwegian Atlantic Current (NwAC) interface. The Lagrangian particle dispersal simulation model further enabled us to assess the large-scale transport of MPs from the Northern European waters to the Arctic.

Research of synergistic effect of magnetic powder and biosurfactant in pollutants removal and membrane fouling alleviation

This study constructed a rhamnolipid-magnetic membrane reactor (RL-MMBR) coupled system to investigate the effects of RL and magnetic powder on membrane fouling alleviation and wastewater treatment efficiency. The optimal concentration was determined by comparing the effects of different concentrations of RL and magnetic powder as well as single and mixed injection on the operation performance. The effects of RL and magnetic powder on pollutant degradation and membrane fouling were investigated at the optimum concentration (300 mg/L RL + 120 mg/L Fe3O4). It was found that the time for TMP to reach 30 kpa in RL-MMBR was 7 days longer than that in CMBR. In the RL-MMBR, the concentration of SMP declined from 13.22 mg/L to 6.75 mg/L and the concentration of LB-EPS decreased from 14.37 mg/L to 7.95 mg/L, and their concentration in RL-MMBR was gradually lower than that in CMBR. But the concentration of TB-EPS in RL-MMBR was always greater than that of CMBR. The sludge particle size in RL-MMBR was gradually larger than that in CMBR. The overall COD removal rate of RL-MMBR (95 %-98 %) was better than that of CMBR (91 %-95 %). The synergistic effect increased the species abundance and diversity of microorganisms in the sludge mixture, but reduced the enrichment of microorganisms on the membrane, especially reduced the adhesion of high-viscosity microorganism Proteobacteria to the membrane. The RL-MMBR coupled system improved the degradation efficiency and alleviated the membrane fouling. In addition, the direct dosing of the agent increased the convenience of operation, the recycling of the magnetic powder reduced the operating cost, and the reaction had no secondary pollution. This provided new ideas and theoretical guidance for solving membrane fouling problems in MBR treatment of domestic sewage.

Contamination of sea surface water offshore the Tokai region and Tokyo Bay in Japan by small microplastics.

A nested double neuston net was prepared and used to collect samples from the surface of coastal waters around Japan to obtain information about the properties of both small microplastics (SMPs; <350μm) and large microplastics (LMPs; >350μm). The SMP concentrations ranged from 1000 to 5900 pieces m-3 in the open ocean and averaged approximately 3000 pieces m-3 in the inner part of Tokyo Bay. The SMP concentrations were around 20-60 times greater than the LMP concentrations. By analyzing the seawater, we obtained a microplastic size distribution that spanned 50-5000μm. The LMPs mainly comprised packaging-related plastics, such as polyethylene (PE) and polypropylene, while the SMPs were dominated by paint-related plastics. SMPs derived from packaging materials (e.g., PE) may have gradually sank down from the sea surface when they were smaller than 600μm.

An integrated hydrodynamic-biokinetic model to optimize the treatment processes in a laboratory-scale, pilot-scale, and full-scale bioreactor

One major disadvantage of membrane bioreactors (MBRs) is the high operating and aeration costs, and optimizing the process to attain economic efficiency is essential. In this study, a hydrodynamic - biokinetic integrated model was developed by combining a multiphase computational fluid dynamics (CFD) model with a population balance (PBM) submodel, an activated sludge (ASM1) submodel, and a combined (EPS – SMP) CES submodel. The developed integrated model was used to investigate the efficiency of treatment of bioreactors on three different scales (case 1- laboratory, case 2 – pilot, and case 3- full-scale system). The simulated values of bubble size count, total chemical oxygen demand (TCOD), total nitrogen (TN), ammonical nitrogen (SNH), nitrate‑nitrogen (SNO), EPS, and SMP concentrations were well validated with the experimental results, with an error percentage of 2.8 %, 6.32 %, 2.25 %, 0.53 %, 1.19 %, 4.62 %, and 2.05 %, respectively. The validated model is then extended for sensitivity analysis to identify optimum conditions (H/B ratio, H/S ratio, and bubble size) to reduce TCOD and TN concentration. The maximum percentage reduction in TCOD and TN concentrations in the most optimum scenario was 20 and 23 %, respectively, for case 3. Also, a reduction of 32 % in the cost of aeration was observed (for case 3) when the bubble size was reduced to 5 mm (from the current value of 7 mm). The preceding results suggest that the integrated model successfully optimized the treatment processes.

Evaluation of membrane fouling in a microalgal-bacterial membrane photobioreactor: Effects of SRT

As a novel system, the microalgal-bacterial membrane photobioreactor (MPBR) has better performance than the conventional MBRs in membrane fouling control. Nevertheless, how the operating conditions affect its fouling performance is rarely reported. In this study, a microalgal-bacterial MPBR was set and continuously operated to treat synthetic wastewater. Effects of solids retention time (SRT, 10, 20, and 30 d) on the membrane fouling were investigated. The results showed that the relationship between membrane fouling and SRT was nonlinear and the fastest membrane fouling was observed at SRT 20 d. The predominant fouling mechanism was gel layer formation. X-ray photoelectron spectroscopy results showed a significant difference in the surface composition of the microalgal-bacterial consortia at different SRTs. The biological flocs at SRT of 20 d had the largest floc size, moderate filament abundance, and the highest content of bound EPS and SMP. The highest membrane fouling at SRT 20 d was mainly attributed to the highest concentration of EPS and SMP. Environmental stresses and fierce competition between microalgae and bacteria are considered to be the underlying reasons for the elevated production of EPS and SMP. In brief, optimizing the SRT value to control the balanced growth of microalgae and bacteria and keep them at an appropriate ratio is critical for delaying membrane fouling in microalgal-bacterial MPBR.

Improving sulfonamide antibiotics removal from swine wastewater by supplying a new pomelo peel derived biochar in an anaerobic membrane bioreactor

Sulfonamide antibiotics (SMs), as a class of antibiotics commonly used in swine industries, pose a serious threat to animal and human health. This study aims to evaluate the performance of an anaerobic membrane bioreactor (AnMBR) with and without supplying a new pomelo peel derived biochar to treat swine wastewater containing SMs. Results show that 0.5 g/L biochar addition could increase more than 30% of sulfadiazine (SDZ) and sulfamethazine (SMZ) removal in AnMBR. Approximately 95% of chemical oxygen demand (COD) was removed in the AnMBR at an influent organic loading rate (OLR) of 3.27 kg COD/(m3·d) while an average methane yield was 0.2 L/g CODremoved with slightly change at a small dose 0.5 g/L biochar addition. SMs inhibited the COD removal and methane production and increased membrane fouling. The addition of biochar could reduce the membrane fouling by reducing the concentration of SMP and EPS.

Acute impact of Hg2+, Cu2+, and Ag+ on the formation of biopolymers and nitrogenous soluble microbiological products in activated sludge for wastewater treatment

In the present work, acute impact of heavy metals on activated sludge was investigated, specifically the release of biopolymers and nitrogenous soluble microbiological products (N-SMP) that significantly impact tertiary effluent quality. Based on the previously reported studies, Hg2+ and Ag+ were selected as representative “non-essential” heavy metals, while Cu2+ was selected as the “essential” heavy metal. Stress tests show that under the present experimental conditions, adding a higher concentration of heavy metals to the activated sludge increases the concentration of biopolymers and SMP in the supernatant; N-SMP increased more significantly than carbonaceous products, implying a greater risk of formation of toxic nitrogenous disinfection by-products or membrane fouling in relevant tertiary treatment processes. The severity of the release of SMP into the supernatant depended on the heavy metal, with an order of Hg2+ > Ag+ > Cu2+ (“non-essential” > “essential”) under identical molar concentrations. The mass balance of typical organics (e.g., biopolymers) in SMP and extracellular polymeric substances (EPS) in activated sludge was analyzed, and a negative correlation between the organics in the SMP and tightly bound EPS was observed, implying that a significant fraction of the SMP could be quickly released from the tightly bound EPS under heavy metal shock conditions and could be related to cell response or damage.

Removal of pharmaceutical compounds commonly-found in wastewater through a hybrid biological and adsorption process

Nowadays, alternative options to conventional wastewater treatment should be studied due to rising concerns emerged by the presence of pharmaceuticals compounds (PhCs) in the aquatic environment. In this work, a combined system including biological treatment by activated sludge plus adsorption with activated carbon is proposed to remove three selected drugs (acetaminophen (ACT), caffeine (CAF) and ibuprofen (IBU)) in a concentration of 2 mg L−1 of each one. For it three sequencing batch reactors (SBR) were operated. SBR-B treated a synthetic wastewater (SWW) without target drugs and SBR-PhC and SBR-PhC + AC operated with SWW doped with the three drugs, adding into SBR-PhC + AC 1.5 g L−1 of a mesoporous granular activated carbon. Results showed that the hybrid system SBR-activated carbon produced an effluent free of PhCs, which in addition had higher quality than that achieved in a conventional activated sludge treatment in terms of lower COD, turbidity and SMP concentrations. On the other hand, five possible routes of removal for target drugs during the biological treatment were studied. Hydrolysis, oxidation and volatilization pathways were negligible after 6 h of reaction time. Adsorption route only was significant for ACT, which was adsorbed completely after 5 h of reaction, while only 1.9% of CAF and 5.6% of IBU were adsorbed. IBU was the least biodegradable compound.

Endogenous intoxication markers of deep-pregnant cows as predictors of pneumonia in newborn calves

The aim of the work was to analyze the indices of endogenous intoxication in deep-pregnant cows and to identify the possibilities of their use as predictors of bronchopulmonary pathology in newborn calves. 29 cows were examined for 239-262 days of gestation and 29 newborn calves of the red-and-white Holstein breed. Bronchitis developed in all calves during the first month of life, and in 7 newborns it was complicated by pneumonia. Markers of endogenous intoxication of cows were analyzed: total and effective albumin concentration, serum MMP content, Kalf-Kalif leukocyte index of intoxication (LII); toxicity index (IT), the ratio of intoxication (CI). The MMP level in cows whose calves did not develop pneumonia was 0.4080.152 units. Cows whose calves developed pneumonia showed a significantly higher content of SMP (0.6150.977 units, p 0.05). Correlation between the concentration of the MMP and the probability of pneumonia (rs=0.536, p0.005) was found. The leukocyte intoxication index of Kalf-Kalif and the toxicity index (IT) in both groups of cows varied significantly; no differences between groups were found. The coefficient of intoxication in cows whose calves developed pneumonia (CI=26.58.4), statistically significantly (p0.05) exceeded CI in cows whose offspring had uncomplicated bronchitis (CI=17.26,8). Correlation between the CI in cows and pneumonia in their offspring (rs = 0.568, p 0.001) was found. The content of the MMP in blood of pregnant cows can serve as a predictor of pneumonia in newborn calves (AUC=0.782, sensitivity 85.71%, specificity 81.82%, critical value 0.547 units). The diagnostic value of the CI predictor is rated as very good (AUC=0.812); sensitivity 71.43%, specificity 86.36%, critical value 22.5. The concentration of SMP in the blood of cows and CI in the period of gestation allows us to predict the development of bronchopulmonary pathology in their offspring with high accuracy.

Small Microplastics As a Main Contributor to Plastic Mass Balance in the North Atlantic Subtropical Gyre.

Estimates of cumulative plastic inputs into the oceans are expressed in hundred million tons, whereas the total mass of microplastics afloat at sea is 3 orders of magnitude below this. This large gap is evidence of our ignorance about the fate of plastics, as well as transformations and sinks in the oceans. One of the current challenges consists of identifying and quantifying plastic particles at the microscale, the small microplastics (SMP, 25-1000 μm). The aim of the present study is to investigate SMP concentration in count and in mass at the sea surface in the North Atlantic subtropical gyre during the sea campaign Expedition 7 th Continent. After isolation, SMP were characterized by micro-Fourier-transform infrared spectroscopy. Microplastic distribution was modeled by a wind-driven vertical mixing correction model taking into account individual particle properties (dimension, shape and density). We demonstrate that SMP buoyancy is significantly decreased compared to the large microplastics (LMP, 1-5 mm) and consequently more susceptible to vertical transport. The uncorrected LMP concentration in count was between 13 000 and 174 000 pieces km-2, and was between 5 and 170 times more abundant for SMP. With a wind-driven vertical mixing correction, we estimated that SMP were 300 to 70 000 times more abundant than LMP. When discussing this in terms of weight after correction, LMP concentrations were between 50 and 1000 g km-2, and SMP concentrations were between 5 and 14 000 g km-2.

Behaviour of fouling-related components in an enhanced membrane bioreactor using marine activated sludge

This paper presents an experimental study on behaviour of fouling-related components during saline wastewater treatments in an enhanced mesoporous membrane bioreactor (MBR) system integrated with a biological contact oxidation reactor (BCOR). By monitoring the transmembrane pressure, the MBR system without BCOR assistance was observed to get membrane fouling easier during saline wastewater treatments. Typically, the concentration of total EPS gradually increased in the MBR system over the operation time, while no significant change in its concentration was observed in the BCOR-MBR system. The concentration of total SMP in the MBR system reached high levels earlier than the BCOR-MBR system, causing a significant membrane fouling. Besides, unlike a simple MBR system, the BCOR-MBR system produced more soluble microbial by-product-like components (simple) instead of fulvic acid-like or humic acid-like components (complex) during the saline wastewater treatments, resulting in higher resistance to a membrane fouling.

Influence of Mg2+ catalyzed granular sludge on flux sustainability in a sequencing batch membrane bioreactor system

The present study was designed to achieve steady state high membrane flux values by controlling the organic and inorganic foulants during MBR operation. Three granular sludge sequencing batch membrane bioreactors, namely, R-1, R-2 and R-3, were run at a constant flux of 40LMH for 90days. R-1 was operated without the addition of Mg2+, R-2 with a continuous dosage of 50mg/L Mg2+, whereas R-3 was run with stoichiometric amounts of Mg2+ (18–22mg/L) in correlation with SMP contents. The particle sizes of aerobic granules were approximately 725 and 600μm in R-2 and R-3, respectively, compared with 250μm in R-1. The ratios of EPS proteins/polysaccharides in R-1, R-2 and R-3 were 1.63, 3.90 and 3.76, respectively, whereas the SMP concentrations in R-1, R-2 and R-3 were 40, 5 and 5mg/L, respectively. The results highlighted that in R-3, the controlled addition of Mg2+ along with the emergence of aerobic granules tremendously increased the membrane permeability, which was approximately 6 and 3 times higher than R-1 and R-2, respectively. In R-3, a molar ratio of 1:2 between Mg2+ and SMP was found to be optimal for the successful sustainability of high flux values during the long term membrane treatment. FTIR, SEM and ICP spectroscopic investigations revealed that the deposition of fine sludge flocs and high amounts of proteins and polysaccharides on the membrane surface in R-1 and Mg2+ in R-2 were mainly responsible for their low permeability.

Effect of biogas sparging with different membrane modules on membrane fouling in anaerobic submerged membrane bioreactor (AnSMBR)

This study focused on the effect of biogas sparging and different membrane modules such as cylinder shaped, funnel-shaped, and U-shaped on the membrane fouling behavior in a lab-scale submerged anaerobic membrane bioreactor (AnSMBR) which was operated for over 60 days. In order to investigate the membrane fouling behavior, a series of analysis such as SMP, EPS, scanning electron microscopy (SEM), energy dispersive X-ray spectroscopy (EDX), particle size distribution, and filtration resistances were performed. Although the rapid generation of cake layer took placed in case of the absence of biogas sparging, the membrane module design mostly influenced the membrane resistance when biogas sparging was applied. Total resistance was the highest for U-shaped module. The permeate fluxes with biogas sparging were higher about one half and two times than those without biogas sparging. Cylinder-shaped module had the lowest SMP and EPS concentrations followed by U-shaped and funnel-shaped modules under both cases with and without biogas sparging. The total resistances of all membrane modules without biogas sparging were found to be very high compared the pore blocking resistances (Rp).

Transient Performance of MBR with Flux Enhancing Polymer Addition

The polymeric membrane performance enhancer (MPE50) was applied in two parallel submerged membrane bioreactors to test its effect on membrane fouling. Although the flux enhancer showed significant benefit, the effect of dosage termination caused a dramatic drop in performance relative to the control. The MBRs were compared in three carefully controlled runs performed over 155 days. The total organic carbon (TOC), EPS, and particle size data were collected at regular intervals during the entire operation. In run 1, after a start-up period of 62 days, a stable state was achieved in both MBRs. In run 2, a one-off 400 mg/L MPE and 15 mg/L MPE daily maintenance dosage were applied in one reactor for 60 days. The “critical flux” determined by the flux stepping test was increased by 50% from 20 LMH to 30 LMH after the addition of MPE. Long-term experiments were implemented at three separate levels of constant flux, namely 20, 30, and 40 LMH. At the flux of 20 LMH (below the “critical flux” of both reactors with and without MPE), the performance in both reactors was similar. At the flux of 30 LMH (above the “critical flux” of the MBR without MPE but below the “critical flux” of the MBR with MPE), the addition of MPE was found to mitigate membrane fouling. At a flux of 40 LMH (above the critical flux for both reactors), the TMP rise in the MBR with MPE was slower than the MBR without MPE, although the performance of both MBRs was poor. The performance differences correlated with the increase in the particle size distribution of the activated sludge as well as the low level of SMP and EPS (mainly polysaccharides) concentrations in the supernatant during steady state. In run 3, after terminating the MPE addition, the membrane performance was found to be significantly worse than the MBR without MPE, which suggests that the continuous maintenance dose of MPE is essential upon MPE application to the MBR.

Filterability of membrane bioreactor (MBR) sludge: impacts of polyelectrolytes and mixing with conventional activated sludge

The main objective of this work was to investigate the filterability of MBR sludge and its mixture with conventional activated sludge (CAS). In addition, the impacts of type and dose of various polyelectrolytes, filter type and sludge properties on the filterability of both MBR and Mixed sludges were determined. Specific cake resistance (SCR) measured by the Buchner funnel filtration test apparatus and the solids content of the resulting sludge cake were used to assess the dewaterability of tested sludges. The type of filter paper used in Buchner tests affected the results of filterability for MBR, CAS and Mixed sludges. SCR values and optimum polyelectrolyte doses increased with increasing MLSS concentrations in the MBR, which suggested that increase in MLSS concentrations accompanied by increases in EPS and SMP concentrations and a shift toward smaller particles caused poorer dewaterability of the MBR sludge. The significant differences observed among the filterability of CAS and MBR sludges suggested that MLSS alone is not a good predictor of sludge dewaterability. Combining CAS and MBR sludges at different proportions generally improved their dewaterability. Combining MBR sludges having typically high MLSS and EPS concentrations with CAS having much lower MLSS concentrations may be an option for full-scale treatment plants experiencing sludge dewaterability problems. Better filterability and higher cake dry solids were achieved with cationic polyelectrolytes compared to anionic and non-ionic ones for all sludge types tested.

Fractionation of proteins and carbohydrates of extracellular polymeric substances in a membrane bioreactor system

The major operational problem associated with membrane bioreactors (MBR) is membrane fouling, for which extracellular polymeric substances (EPS) are primarily responsible. In this work both the soluble and bound EPS (i.e. SMP and EPS) produced in an MBR system operating under sludge retention times (SRT) of 10, 15, 20 and 33 days were fractionized by means of membranes having variable molecular weight cutoffs (300 kDa, 100 kDa, 10 kDa & 1 kDa). The results show that increasing the SRT leads to a reduction of SMP and EPS and that these reductions are more pronounced for the SRTs in the range 10–20 days. This reduction is more significant for carbohydrates than for proteins. The decrease of SMP and EPS with increasing SRT from 10 to 20 days led to a significant decrease of the level of fouling. The further increase of SRT to 33 days did not significantly impact on the level of fouling as the SMP and EPS concentrations did not change much. Under the examined operating conditions, EPS were found to be composed mainly of large macromolecules having a size of 0.45 μm–300 kDa and to a lower extent of very small molecules (<1 kDa) that are not easily decomposed by the biomass activity. The majority of SMP is composed of very small molecules (<1 kDa), while some macromolecules in the range of 0.45 μm–300 kDa are present. Consequently, both EPS and SMP were found to have a bimodal character.

Effect of Membrane Pore Size on Membrane Biofouling in Ceramic Membrane Bioreactors

Effect of Membrane Pore Size on Membrane Biofouling in Ceramic Membrane BioreactorsFour SCMBRs were operated in parallel to investigate the treatment performance and fouling potential of ceramic membranes in MBRs. Results showed that the SCMBR was able to provide good permeate quality with COD less than 20 mg/L. The effect of the sludge characteristics such as MLSS, SMP and EPS concentrations on membrane fouling were not significant when all the systems were operated under the...Author(s)Le JinHow Yong NgSay Leong OngSourceProceedings of the Water Environment FederationSubjectSession 106 - Global MBR Research Colloquim: Part II - Novel and Full Scale ApplicationsDocument typeConference PaperPublisherWater Environment FederationPrint publication date Jan, 2009ISSN1938-6478SICI1938-6478(20090101)2009:8L.7069;1-DOI10.2175/193864709793957553Volume / Issue2009 / 8Content sourceWEFTECFirst / last page(s)7069 - 7078Copyright2009Word count140Subject keywordsCeramic membranePore sizeSMPEPSBiocake/Biofilm

SPREAD OF SULFANILAMIDOMETHYLPYRIMIDINE THROUGH THE CEREBROSPINAL FLUID

Foi estudada a relação entre as concentrações de 2-sulfaniIamido-5-metilpirimidina (SMP) no LCR e no sangue após a administração oral da droga a 30 pacientes. Do total, 19 apresentavam LCR normal e eram portadores de afecções crônicas não inflamatórias do sistema nervoso. Nos restantes o LCR apresentava alterações de tipos diversos; 4 eram portadores de polirradiculoneurite; um, de meningite crônica; um, de neurolues; 5, de neurocisticercose. Os resultados referentes aos pacientes com LCR normal mostraram que há correlação estatisticamente significativa entre as taxas de SMP no LCR e no sangue. A concentração de SMP no LCR é cêrca da quinta parte da encontrada no sôro. Entre os pacientes com LCR alterado foi encontrado aumento da relação em dois casos de polirradiculoneurite; em ambos havia concentração elevada de SMP no LCR. Nos demais os valôres encontrados para a relação não se afastavam daqueles verificados para pacientes com LCR normal.