Objective To assess the effect of parent-child individual management in children with mycoplasma pneumonia and to provide guidance for improve the quality. Methods 482 children with mycoplasma pneumonia were divided into parent-child individual management group and conventional intervention group according to the time including the study.The parent-child individual management group used specially formulated for the mother and child management intervention + conventional measures.The conventional intervention group used conventional nursing measures.The duration of hospitalization, hospitalization expense, depression, family members of patients satisfaction, curative effect, clinical index were compared between the two groups. Results After intervention, compared with the conventional intervention group, the duration of hospitalization, hospitalization expense decreased lower[length of stay: (12.08±1.26)d vs.(15.82±3.07)d, t=16.398, P=0.000; hospitalization expense: (641.57±124.28) RMB vs.(896.72±179.15)RMB, t=17.012, P=0.000], the maternal anxiety of the parent-child individual management group reduced obviously[anxiety scores (34.21±4.51)points vs.(43.29±6.17)points, t=17.245, P=0.000]and the satisfaction of children of the parent-child individual management group improved obviously(most satisfaction rate: 65.71% vs.49.52%, χ2=10.663, P=0.001; satisfaction rate: 27.14% vs.29.25%, χ2=0.928, P=0.710; general satisfaction rate: 5.71% vs.16.04%, χ2=10.538, P=0.000; dissatisfaction: 1.43% vs.5.19%, χ2=3.552, P=0.060; total rate: 92.86% vs.78.77%, χ2=16.021, P=0.000). The efficacy of the parent-child individual management group improved obviously(inefficiency: 7.14% vs.21.22%, χ2=16.021, P=0.000; efficiency: 17.19% vs.21.21%, χ2=1.812, P=0.178; cure rate: 73.33% vs.53.30%, χ2=17.364, P=0.000; total effective rate: 92.85% vs.78.77%, χ2=16.021, P=0.000). The clinical indicators of the parent-child individual management group were improved obviously[pyretolysis days: (3.42±1.46)d vs.(4.56±1.67)d, t=7.463, P=0.000; cough disappeared days: (8.72±2.04)d vs.(10.29±1.95)d, t=8.030, P=0.000; rales disappeared days: (3.96±1.45)d vs.(5.87±1.71)d, t=12.370, P=0.000]. Conclusion The parent-child individual management in children with mycoplasma pneumonia has good effect on the hospitalization days, hospitalization expense, the satisfaction of children, the curative effect and the clinical indicators, it is worthy of clinical promotion. Key words: Nursing administration research; Mycoplasma pneumonia; Child