Purpose: With the advent of COVID-19 era, teaching activities have migrated from offline to online platform. In this study, we assess whether the increased exposure to visual display terminal (VDT) devices is affecting the health of school-age children with regard to computer vision syndrome (CVS). Methods: This cross-sectional study was carried out by means of an online questionnaire. Participants were students ranging from Class 1 to Class 12. Questions were posed to participants pertaining to screen exposure time, physical activity levels, dry eye symptoms, and asthenopia symptoms. The dry eye part was adapted from the 5 Item Dry Eye Questionnaire (DEQ5 questionnaire), and the asthenopia part was adapted from the questionnaire developed by Ames et al. A total of 554 students were included in the study. The data received were statistically analyzed. Results: An increase in screen exposure time during COVID era was reported by 237 (42.8%) students. The major contributors to screen usage were online classes and assignments (94% of students). The prevalence of headache was higher in students using tablet/iPad and smartphone as the VDT device. The headache, eyeache, DEQ5 scores, and asthenopia scores were significantly correlated with screen exposure time, and a significant increase was observed in parameters from pre-COVID to COVID era. Concentration span in online classes showed a positive correlation with amount of physical activity of the student. Conclusions: Dry eye, asthenopia, and musculoskeletal symptoms of CVS have increased significantly during COVID era. Screen exposure needs to be restricted and adequate attention needs to be given to physical activity.