Introduction. Modern medium (10–200 microns) and fine (0.1–10.0 microns) powders have a high cost, which limits the scale of their production and use. This assumes the implementation the latest achievements in the field of creating new equipment that is not inferior in its technical characteristics to the best foreign models into industry. The use centrifugal mills of vertical type for grinding various raw materials has shown their high efficiency in obtaining materials in the range – 0.2–0.01 mm. Studies of these mills operation under various operating conditions made it possible to create a large data set on the dependence of the crushed material granulo-metric composition on the design features of the mills and technological parameters of the grinding process. The results of a previously study of the granulo-metric composition a finely dispersed crushed product integral distribution according to particle size classes less than 80 microns were presented. They were obtained in a Brookhaven BI-XDC X-ray analytical centrifuge by measuring particle sizes in natural sedimentation mode, when the centrifuge disk was stationary during the experiment. The studies of the particle size differential distribution of a finely dispersed crushed product according to particle size classes less than 80 microns, which have not been carried out to date are of particular interest. Purpose of the study. The differential distribution study of the finely dispersed granulo-metric product composition obtained by grinding lump dolomite in a centrifugal mills of vertical type under different operating modes. Materials and methods. To solve this problem, samples of crushed material were taken from grinding dolomite from the Bosninsky deposit (RNO-Alania) in a centrifugal mill of the vertical type MV-0.3 with a 300 mm rotor diameter with following technological modes of the grinding process: mill rotor speed n = 310; 360 min–1, height of the material column above the rotating rotor H = 180; 270 mm, test time – 6 hours. Selected samples with a size class of –0.08 mm were analyzed in an X-ray analytical centrifuge Brookhaven BI-XDC, designed to determine the particle size distribution in the range from 0.01 to 100 microns. The measurements were performed on a suspension prepared from a mixture of 0.5 g of the selected sample with a 20% solution of sucrose and distilled water. Samples with a size class of 0.08 mm were weighed on laboratory scales LV SP.005.048 RE. The resulting suspension was dispersed in an ultrasonic bath for 3–5 minutes. After dispersion, the suspension was poured into the analyzer disk. While stirring, the lower absorption baseline line of a homogeneous particle suspension was measured. The obtained data from the analysis of the fine fractions size of were processed by the centrifuge computer software and graphs of the differential distribution of particles were constructed for various technological modes of grinding dolomite in a centrifugal mill. During the processing of the experiments, minor bursts in the concentration of the crushed product were not taken into account. The results and discussion. For the first time, a differential analysis of the granulo-metric composition of finely dispersed material with a particle size of –0.08 mm, obtained by grinding lump dolomite in a centrifugal mill of the vertical type under different mill operating modes, was carried out. Under all investigated operating modes of the centrifugal mill, the main part of the fine fraction in the mill outlet was in the range from 1.197 to 4.643 μm, and in steady-state operation it varied from 1.310 to 4.601 μm. The range of fine particle sizes has maximum values when the height of the column of crushed material above the rotating mill rotor and the rotation speed of the mill rotor decrease, and minimum values are observed when the height of the column of crushed material above the rotating mill rotor increases and the rotation speed of the mill rotor increases. Resume. 1. The article presents the results of the granulo-metric composition differential distribution study of a finely dispersed product obtained by grinding lump dolomite in a centrifugal mill of the vertical type. 2. The conducted studies have shown that, despite the positive results in obtaining fine particles with a size of 0.001 microns (nanoparticles) by mechanical means, the industrial production of nano-materials when grinding lump mineral raw materials in a vertical centrifugal mill is not economically profitable due to the low specific productivity and high energy intensity of the grinding process. 3. The obtained research results can be useful in the design of centrifugal mills.