The hyperdense middle cerebral artery sign (HMCAS) is a useful clinical sign in the management of acute stroke and may alter time-critical decisions within an emergency setting. Though gold standards have been published, these are rarely used in clinical practice and scans tend to be reported subjectively. It is therefore possible that the level of experience of the doctor reporting the scan may impact on accuracy of reporting and hence patient management. This study aimed to evaluate accuracy in detecting HMCAS across doctors with varying levels of experience. Forty doctors were recruited into four categories of experience. Each subject received a brief computer-based tutorial on how to identify an HMCAS and was then asked to report on the presence or absence of an HMCAS in 19 pre-prepared CT scans using a standardised viewing template. Mean ± standard error percentage correct scores increased with experience from 76.8 ± 3.69 among interns and residents to 90.1 ± 2.23 among neurologists and radiologists (p
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