Abstract The preliminary design of labyrinth seals requires fast and accurate estimate of the leakage flow. While the conventional bulk flow models can quickly predict labyrinth seal discharge characteristics, they lack the accuracy and pragmatism of modern computational fluid dynamics (CFD) techniques and vice-a-versa. This paper presents a new one-dimensional loss model for straight-through gas labyrinth seals that can provide quick seal leakage flow predictions with CFD-equivalent accuracy. The present seal loss model is developed using numerical experimentation technique. Multiple CFD computations are conducted on straight-through labyrinth seal geometries for a range of pressure ratios. A distinct postprocessing methodology is developed to extract the through-flow stream tube in seal. Total pressure losses and flow area variations experienced by the flow in seal stream-tube are systematically accounted for based on the well-known knife-to-knife (K2K) methodology. Regression analyses are conducted on the trends of variations of loss and area coefficients to derive the independent pressure loss and flow area correlations. These novel correlations can predict the bulk leakage flow rate, windage flow rate, and interknife static pressures over a wide range of variations of flow and geometry parameters. Validation study shows that the leakage mass flow rate predicted by this model is accurate within ±8% of measured test data. This fast and accurate model can be employed for various applications such as in seal design-analysis workflows, for secondary air system (SAS) performance analysis, and for the rotor-dynamic and aeroelastic assessments of seals.