The study of the behavior of bioconvective nanofluid model (BC-NFM) was explored using bioconvection properties in the computational analysis of magnetized nanofluid flow that was convectively heated, which is critical for applications in energy systems and biomedical devices. We implemented a backpropagated Levenberg–Marquardt neural network approach (BLMNNA) to enhance the analysis and prediction accuracy of such fluid flows. Using the Adams numerical technique, we generated a comprehensive dataset for eight distinct scenarios by variation of thermophoresis parameter, Rayleigh number, Deborah parameter, Hartman number, Prandtl number, bioconvection Lewis number, and Schmidt number to train and test our model. The results demonstrate significant improvements in prediction accuracy and computational efficiency compared to traditional numerical solvers. The steps of training, testing, and validating the developed BLMNNA are used to get the desired numerical solutions of BC-NFM for various instances. The worth and accuracy of the stochastic numerical solutions of BC-NFM are established and authenticated by the outputs of the designed methodology BLMNNA through Adaptation graphs of Mean Square Error, regression studies, plots of error histogram and index of state transition. Excellent measurements of performance in terms of MEAN SQUARE ERROR are achieved at level 9.76E[Formula: see text], 1.41E[Formula: see text], 1.79E[Formula: see text], 1.22E[Formula: see text], 8.49E[Formula: see text], 7.19E[Formula: see text], 9.72E[Formula: see text], and 9.35E[Formula: see text] against 69, 73, 96, 76, 237, 86, 120, and 33 epochs. The significant connection between the proposed and reference findings demonstrates the validity of the BLMNNA based on error analysis, which ranges from E[Formula: see text] to E[Formula: see text] for all situations. The results show that the proposed neural network approach achieves a high level of accuracy, closely matching the outcomes obtained from the numerical solver. The method provides an efficient and precise solution for the analysis of complex fluid flow problems, representing a significant advancement over traditional numerical techniques.