Lightweight concrete (LWC) is a group of cement composites of the defined physical, mechanical, and chemical performance. The methods of designing the composition of LWC with the assumed density and compressive strength are used most commonly. The purpose of using LWC is the reduction of the structure’s weight, as well as the reduction of thermal conductivity index. The highest possible strength, durability and low thermal conductivity of construction materials are important factors and reasons for this field’s development, which lies largely in modification of materials’ composition. Higher requirements for construction materials are related to activities aiming at environment protection. The purpose of the restrictions is the reduction of energy consumption and, as a result, the reduction of CO2 emission. To limit the scope of time-consuming and often high-cost laboratory works necessary to calibrate models used in the test methods, it is possible to apply Artificial Neural Networks (ANN) to predict any of the concrete properties. The aim of this study is to demonstrate the applicability of this tool for solving the problems, related to establishing the relation between the choice of type and quantity of lightweight aggregates and the porosity, bulk density and compressive strength of LWC. For the tests porous lightweight Granulated Expanded Glass Aggregate (GEGA) and Granulated Ash Aggregate (GAA) have been used.