Concrete-filled steel tube (CFST) columns enhance seismic resistance, enabling lighter-weight structures with improved fire performance. This study investigates the axial performance of cruciform CFST columns using three half-scale experiments. The cruciform sections were internally configured as unstiffened (UnS-CFST), stiffened (S-CFST), and multicell (M-CFST). Failure mode, stress, displacement, ductility, and strength were evaluated to determine the maximum load-bearing capacity. Compared to UnS-CFST columns, S-CFST and M-CFST exhibited improved ductility and axial compressive performance. The study also looks at how the proposed method for cruciform sections compares to existing design standards for square and circular CFST columns, such as AIJ, EC4, GB 50936–2014, CECS 159:2004, ACI 318R-05, and AS3600–2001. A novel method for determining the maximum load capacity of cruciform CFST columns is proposed, achieving an accuracy of approximately 95 % compared to experimental results. This novel method facilitates the design of cruciform CFST columns.