INTRODUCTION: First reported by Rokitansky in 1861, Superior Mesenteric Artery (SMA) Syndrome is a rare medical condition occurring due to compression of third portion of duodenum between the SMA and abdominal aorta (AA).(1) It is often overlooked in medical practice. We describe the case of a 56-year-old F who had intermittent symptoms of nausea, vomiting and abdominal distention, who was found to have SMA syndrome. CASE DESCRIPTION/METHODS: A 56-year-old female was admitted to the hospital with abdominal distention, nausea, vomiting and fatigue. She had symptoms of abdominal distention and bloating for six years that required intermittent hospitalization and was managed conservatively with bowel rest and replenishment of electrolytes. She was cachectic with a BMI of 16 kg/m2. Abdomen was soft and distended with succession splash and normoactive bowel sounds. CT scan of the abdomen showed massively distended fluid filled stomach and narrow aortomesenteric angle (14°) (Figures 1A and 1B). EGD was performed which showed normal appearing patent pylorus and severe stenosis of the third portion of the duodenum with duodenal stenosis appearing to be secondary to extrinsic compression from the superior mesenteric artery (Figures 2A and 2B). She was started on small fractionated meals, low residue diet. Her hospital stay was complicated by sepsis, delirium and multiorgan failure. Due to her overall poor prognosis, she was discharged on hospice. DISCUSSION: The third portion of duodenum (D3) traverses in the area between the abdominal aorta and SMA at the level of L3 vertebra and is suspended at this location by the ligament of Treitz. This area decreases in people with rapid weight loss and cachexia. Symptoms include early satiety, bloating, nausea, intractable vomiting, acid reflux, weight loss, and post prandial upper abdominal pain. The diagnosis is confirmed by computerized tomogram (CT) angiogram of the abdomen demonstrating angle between the origin of the SMA and the AA to be < 22° and aortomesenteric distance less than 10 mm (normal 10–28 mm) (Figure 4). Conservative approach (gastric decompression and replenishment of fluids and electrolytes) is the first line strategy in management, followed by surgery (Duodenojejunostomy is gold standard).(2)Figure 1.: A- Normal appearing pylorus B- Compression of duodenum.Figure 2.: A- Distended stomach. B- narrow aortomesenteric angel and compression of duodenum.
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