Comprehensive Evaluation Of Effects Research Articles

Comprehensive Evaluation of Effects of Various Denture Cleansers on Surface Roughness of Denture Resin: An Original Research Study

Comprehensive Evaluation of Effects of Various Denture Cleansers on Surface Roughness of Denture Resin: An Original Research Study

Three dimensional evaluation on soil improvement effect of saline alkali soil in Yellow River Delta

It is necessary to evaluate the effect of soil improvement after land consolidation for productivity improvement, but the current evaluation method is relatively single. In this paper, based on the data of soil salt content from monitoring and sampling, the statistical characteristics were analyzed by SPSS software, and the three-dimensional distribution map was constructed by using GMS10.0 software for IDW interpolation. The results showed that the soil salt content in 2019 decreased significantly by 31.29% compared with that in 2018 from the characteristics of cultivated layer, and the effect of soil improvement was obvious. From the profile characteristics, the soil salt content in the study area is characterized by “surface accumulation”. The salt content of soil profile decreased significantly at maize maturity stage compared with that before sowing. The decrease rates of soil salt content at different depths were 70.11% (0-20cm), 77.43% (20-40cm), 77.31% (40-60cm), 83.34% (60-80cm) and 65.26% (80-100cm), respectively. The decrease rate of 60-80cm soil layer was the largest. The results can be used as a reference for single index or comprehensive index three-dimensional visualization evaluation of soil improvement effect.

Comprehensive evaluation of wealth effects on local labor market outcomes

Comprehensive evaluation of wealth effects on local labor market outcomes

Control Strategy and Experimental Research of Cable-Driven Lower Limb Rehabilitation Robot

The passive training with fixed trajectory is more suitable for the initial rehabilitation training of patients with no muscle strength in the affected limb. In order to meet the needs of patients' rehabilitation training in different rehabilitation stages and improve the active participation and rehabilitation training effect of patients, a fuzzy sliding mode variable admittance (FSMVA) controller based on safety evaluation and supervision is proposed for the cable-driven lower limb rehabilitation robot (CDLR) in this paper. The FSMVA controller consists of an inner loop fuzzy sliding mode controller, an outer loop variable admittance controller, and a safety evaluation and supervision module. Through the safety evaluation index of the CDLR system and the comprehensive evaluation of patients' rehabilitation effect given by rehabilitation physiotherapists, a real-time adjustment algorithm of variable admittance controller parameters is designed, which can realize the real-time switching of training modes and adjustment of variable admittance controller parameters in active training mode and passive training mode. The trajectory tracking experiments with no admittance, fixed admittance, and variable admittance based on safety evaluation and supervision were carried out on the experimental platform. The experimental results show that the proposed FSMVA control strategy has high position control accuracy in the active training mode. In addition, the training intensity and the active participation of patients can be increased according to the patient's exercise ability. In the passive training mode, according to the training needs of patients, the amount of the trajectory adjustment can be increased to improve the comfort of the training process and the safety of patients. It lays a foundation for the further study of the evaluation system of the rehabilitation training process and the experiment of human-machine interaction compliance.

Comprehensive evaluation of adverse effects of host modulatory agents: A critical review

Recent advances in study of inflammatory pathways are bringing up new pathways of understanding regarding the bone loss and tissue destruction related to periodontitis. This knowledge, along with the development of novel drugs like host modulatory agents that can inhibit bone loss/destruction, provides us with opportunities to manage not only soft tissue inflammation but also the destructive bone loss occurring during periodontitis. The use of such agents as an adjunct to conventional periodontal therapy, not only minimizes the current periodontal disease severity and improves treatment prognosis, but also reduces future susceptibility to periodontal disease. But there are certain adverse effects secondary to these agents and thus this literature review sheds light on some of these adverse reactions which are known to be caused by these novel drugs

Evaluation of fusion methods for GF-6 aiming to water body observation

Gaofen-6 (GF-6) has the advantages of wide coverage, multiple resolutions, and multiple bands, and can provide richer information for remote sensing interpretation. Image fusion method is the key process in high resolution remote sensing application. Guangdong-Hong Kong-Macao Greater Bay Area was selected as experiment area and four image fusion methods of HPF (High-Pass Fliter), NND (Nearest Neighbor Diffusion), GS (Gram-Schmidt) and Pansharp were employed to process panchromatic and multispectral imaging. In order to evaluate the result performances, firstly, four kinds of fusion results were evaluated by visual，and then established mean, standard deviation, entropy, average gradient, correlation coefficient and spectral distortion for quantitative evaluation of fusion results. The results demonstrated that The Pansharp algorithm and the GS algorithm have the best comprehensive evaluation of the GF-6 satellite fusion effect, taking into account the color effect of the image and the enhancement of spatial details, which can meet most fusion requirements. For land-based fusion areas, the Pansharp fusion method can be selected, and the GS fusion method can better reflect the water body information and is the most suitable fusion method for GF-6 satellite water body information enhancement among the four algorithms.

On the Issue of a Comprehensive Evaluation of the Effectiveness of Using Airship Systems As a Means of Rescuing Space Crews.

This paper presents approaches to selecting criteria and conducting a com-prehensive evaluation of the comparative effectiveness of using manned innovative dirigibles in the search and rescue system for space crews in various climatic and geographical zones. The evaluation can be carried out for existing and prospective means that provide the ground, sea and aviation components of nominal and emergency search and evacuation of crews of new-generation manned transport spacecraft in the conditions of the Vostochny cosmodrome, which are characterized by special natural and geographical parameters.

PEGylated gold nanoparticles promote osteogenic differentiation in in vitro and in vivo systems

Gold nanoparticles (GNPs) have attracted considerable attention in promoting osteogenic differentiation. However, little is known about their osteogenic effects on cells from various origins, and further in vivo investigation as a promising osteogenic agent upon hydrogel-conjugation is required. Herein, the effects of PEGylated GNPs with the sizes of 4, 18 and 45 nm on osteogenic differentiation in the pre-osteoblastic MC3T3-E1 cell line, human bone marrow-derived mesenchymal stem cells (hBMSCs) and rat bone marrow-derived mesenchymal stem cells (rBMSCs) were comprehensively evaluated. The results showed that GNPs with all of three different sizes had excellent biocompatibility, and their effects on induction of osteogenic differentiation of various cell types were dependent on size. Specifically, 45-nm GNPs showed more pronounced alkaline phosphatase (ALP) activity, mineralized nodule formation and expression of osteogenic marker genes compared with the 18-nm group, while 4-nm GNPs reduced the above osteogenic effects. Meanwhile, β-catenin and p-GSK-3β were upregulated by GNPs-45 nm and GNPs-18 nm, but suppressed by GNPs-4 nm, indicating that Wnt/β-catenin signaling pathway mighy play an important role in GNPs-induce osteogenic differentiation. In addition, specific blocking of Wnt/β-catenin signals by KYA1797K inhibited 45 nm GNPs-induced osteogenic differentiation of MC3T3-E1 cells. Furthermore, 45-nm GNPs conjugated with PEG-hydrogel were chosen for in vivo bone regeneration testing in rabbits with 4-mm femur defects. The results demonstrated that the GNPs stimulated bone regeneration rapidly and effectively. Such comprehensive evaluation of GNPs' effects on in vitro osteogenic differentiation and in vivo bone regeneration could promote their applications in clinical translation.

Economic Analysis of Limited Water Irrigation on Wheat Yield

Zhou, B. and Yang, H., 2020. Economic analysis of limited water irrigation on wheat yield. In: Guido Aldana, P.A. and Kantamaneni, K. (eds.), Advances in Water Resources, Coastal Management, and Marine Science Technology. Journal of Coastal Research, Special Issue No. 104, pp. 637–640. Coconut Creek (Florida), ISSN 0749-0208.There are some problems in traditional wheat irrigation, such as high cost of wheat irrigation, high energy consumption and poor yield. Therefore, the economic analysis of wheat yield by limited water irrigation was put forward. This paper analyzes the situation of wheat planting in China and the irrigation mode of wheat planting, and analyzes the influence of water limited irrigation method on wheat yield; obtains the water demand of each stage of wheat growth, constructs the comprehensive effect evaluation model of water limited irrigation, and carries out comprehensive evaluation on wheat yield; on the basis of the above analysis, the grey correlation model is constructed to analyze the coupling between water limited irrigation and wheat yield. The comprehensive effect evaluation model of water limited irrigation was optimized, and the economic analysis of limited water irrigation on wheat yield was completed. The results showed that the irrigation cost was lower, the irrigation time was shorter, and the yield of wheat was higher.

Design and methods of NYC care calls: An effectiveness trial of telephone-delivered type 2 diabetes self-management support

Although problems with type 2 diabetes (T2D) self-management and treatment adherence often co-occur with emotional distress, few translatable intervention approaches are available that can target these related problems in primary care practice settings. The New York City (NYC) Care Calls study is a randomized controlled trial that tests the effectiveness of structured support for diabetes self-management and distress management, delivered via telephone by health educators, in improving glycemic control, self-management and emotional well-being among predominantly ethnic minority and socioeconomically disadvantaged adults with suboptimally controlled T2D. English- and Spanish-speaking adults treated for T2D in NYC primary care practices were recruited based on having an A1C ≥ 7.5% despite being prescribed medications for diabetes. Participants (N = 812) were randomly assigned to a telephonic intervention condition with a stepped protocol of 6–12 phone calls over 1 year, delivered by a health educator, or to a comparison condition of enhanced usual care. The primary outcome is change in A1C over one year, measured at baseline and again approximately 6- and 12-months later. Secondary outcomes measured on the same schedule include blood pressure, patient-reported emotional distress, treatment adherence and self-management behaviors. A comprehensive effectiveness evaluation is guided by the RE-AIM framework (Reach, Effectiveness, Adoption, Implementation, Maintenance) to gather data that can inform dissemination and implementation of the intervention, if successful. This paper describes the study rationale, trial design, and methodology.

Comprehensive evaluation of the industrial processing effects on the fiber properties of the pulps from wood residues

Abstract Wood processing residue, as an essential forest resource, is underestimated in the industrial applications. With the development of pulping technology, fiber quality and cost control have become the important prospects. It is very crucial to investigate the influencing factors of pulping, designed to reveal the relationship between fiber separation and physical performances. In this study, a range of effect factors of large-scale pulping process, including wood species, pretreatment, mechanical conditions, and post-bleaching treatment, were comprehensively investigated. The results illustrated that the industrial pulping process affected the dimensions of the fibers, their surface morphology, chemical structure, and thermal stability. The separated positions of the fibers were determined collectively by the mechanical temperature, time, and wood species. In addition, mild bleaching could effectively increase the crystallinity index, accessibility of the hydroxyl groups, and water retention values. However, it exerted a negative influence on the thermal stability. Further, chemical-assisted-refinement can replace higher temperature and prolonged ones to obtain pulp fibers with high quality while consuming less energy. Improved knowledge of how the industrial affects the fiber separation of a wood matrix and pulp quality is required as a basis for the development of the pulp and paper industry.

COVID-19: Morphology, Characteristics, Symptoms, Prevention, Clinical Diagnosis and Current Scenario

Background: There are different types of viruses found in nature which cause infection in humans and other animals, some causing severe illness and others not. A unique coronavirus termed severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) was isolated from lower respiratory tract sample as the causative agent. Objective: This review article includes characteristics of COVID-19, current scenario of disease, causes and symptoms of disease and how to prevent from its infection. Methods: We accomplished a comprehensive evaluation of the communication amid COVID-19 disease and serious effects of the disease. There are many articles describing the general characteristics, prevention and its harmful effects on humans which were included. The clinical diagnosis and present scenario of the disease were also reviewed. Results: The recent outbreak of contagions with SARS-CoV-2 is termed Coronavirus Disease 2019 (COVID-19) by the World Health Organization (WHO). Many governments of the world, scholars and scientists are engaged to discover the proper treatment and until a proper and right treatment for it is found, we have to be careful to avoid infection. Conclusion: At present, the whole world is struggling with COVID-19 disease. COVID-19 quickly spread into at least 215 countries and exterminated more than 300,000 persons by May 15, 2020. This is the time to exercise restraint and caution. The rapid extent of disease allows deep examination and quarantine conventions to prevent further transmission.

Comprehensive evaluation of electrocaloric effect and fatigue behavior in the 0.9Pb(Mg1/3Nb2/3)O3–0.1PbTiO3 bulk relaxor ferroelectric ceramic

Electrocaloric refrigeration shows potential as a viable alternative to vapor-compression and/or thermo-electric refrigeration. One of the main challenges that need to be addressed in electrocaloric technology is the fatigue behavior of electrocaloric materials, in terms of both structural and functional aspects. Here, a comprehensive evaluation of the fatigue behavior of the 0.9Pb(Mg1/3Nb2/3)O3–0.1PbTiO3 (PMN-10PT) bulk relaxor ferroelectric (or shortly relaxor) ceramic at room temperature is performed. First, the temperature-change dependence on the slew rate was studied. It is shown that the adiabatic conditions are well approached at the slew rate above 1 kV s−1, at which the adiabatic temperature change of 1.3 K was measured at the electric field change of 90 kV cm−1. Then, the durability limits (i.e., the fatigue life) of ten PMN-10PT samples were investigated during unipolar electric field cycling. The results showed that the material could withstand up to 106 cycles at the electric field change of 90 kV cm−1 with only minor degradation of the functional properties (less than 5% of the maximum adiabatic temperature change). Hence, PMN-10PT can be considered as a promising material for use in an electrocaloric cooling device, but some critical issues that caused premature failure of several samples would need to be further addressed and improved.

Development of the Russian version of quality of life questionnaire in patients with GERD - GERD-HRQL

Development of the Russian version of GERD-HRQL questionnaire to assess symptomatic outcomes of GERD in research and real clinical practice. GERD-HRQL questionnaire (V. Velanovich, USA) consists of 11 items: 10 items for assessment of the most frequent symptoms/problems related with QoL in pts with GERD and 1 item for assessment of patient-reported global satisfaction with health condition. In accordance with international guidelines, the new language version of the tool may be used in research and clinical practice after cross cultural adaptation, linguistic validation and psychometric testing. This paper presents the results of cross-cultural adaptation and linguistic validation of the Russian version of GERD-HRQL. The following steps of linguistic and cultural adaptation of GERD-HRQL for Russia were conducted after the permission from the author of GERD-HRQL was obtained: forward translation with creation of two forward translations of GERD-HRQL in Russian, reconciliation and expert evaluation of translations of GERD-HRQL in Russian and creation of the preliminary version of GERD-HRQL in Russian, back translation, harmonization, creation of the first test-version of GERD-HRQL in Russian, cognitive debriefing and decentering, creation of the second test-version of GERD-HRQL in Russian, final expert evaluation and development of the final test-version of GERD-HRQL in Russian. Satisfactory face validity of the Russian test-version of GERD-HRQL was shown: face validity indices were 0.98, 0.95, 0.92, and 0.97. As the result of translation, cross cultural adaptation and linguistic validation, the Russian version of GERD-HRQL for the use in pts with GERD in Russia was developed. The Russian version of GERD-HRQL may be used in research studies and clinical practice after testing its psychometric properties.

A Comprehensive Evaluation of Mepolizumab Effectiveness in a Real-Life Setting

Introduction: Interleukin-5 (IL-5) is the principal cytokine regulating eosinophil growth, differentiation, activation, and expression. It is a specific target of mepolizumab, an anti-IL-5 monoclonal antibody used in the treatment of severe eosinophilic asthma. This new drug can improve symptoms, reduce asthma exacerbations and steroid use. Few data are available on its efficacy for nasal symptoms. Objective: To describe the all-round clinical impact of mepolizumab in a real-life setting, evaluating the efficacy and safety of the drug in severe eosinophilic asthma patients. Population and Methods: We retrospectively collected the clinical and functional data on 27 patients (16 males) affected with severe eosinophilic asthma, diagnosed at the Siena Regional Referral Centre and monitored for 6 months. Clinical, immunological, and functional data at baseline and follow-up were entered in a database together with comorbidities, number of exacerbations, steroid treatment, multiple-flow exhaled nitric oxide, and validated questionnaires. Results: A significant reduction in asthma exacerbations was observed in all patients after 6 months of the biological therapy (p = 0.0009), and 4/6 patients discontinued chronic oral steroids. A significant improvement in ACT, FEV1, SNOT22, and alveolar nitric oxide was observed after 1 month of mepolizumab (p = 0.003, p = 0.007, p = 0.047, and p = 0.019, respectively) and maintained after 6 months of treatment. After 6 months, FeNO 50 was reduced as well (p = 0.030). Mepolizumab was very well tolerated, and no major side effects were observed. Conclusions: Our study suggests that mepolizumab is effective in improving control of asthma, lung function parameters, exhaled biomarkers, and nasal symptoms in patients with severe eosinophilic asthma.

Treatment Effect Analysis on Shallow Buried Bias Slope Section of Tunnel Based on Fuzzy Comprehensive Evaluation

There is a close interaction relationship between tunnel unsymmetrical loading section and lateral slope, and tunnels and lateral slope should be analyzed synthetically as a synergetic system, thus providing more accurate theoretical basis for taking reasonable and protective measures in practical engineering. This paper is based on treatment project of shallow buried bias section slope of the Niubi Mountain tunnel. Considering the synergetic effect of tunnel and slope, the tunnel engineering index was added into the index system, and the evaluation model system for the treatment effect of shallow buried bias slope section of tunnels was established. According to the index system, the fuzzy comprehensive evaluation model for treatment effect of shallow buried bias slope section of tunnel is established by analytic hierarchy process. The model for fuzzy comprehensive evaluation is used to evaluate the treatment effect of Shallow Buried Bias Slope Section of Niubi Mountain Tunnel and five other similar cases. The evaluation results are consistent with the actual engineering results. Supported by a limited number of samples, the practicability of the proposed model is proved. The model of fuzzy comprehensive evaluation of treatment effect of shallow buried bias slope section of tunnel can be used in similar projects. It can help engineers make decisions during construction.

Nodularin induced oxidative stress contributes to developmental toxicity in zebrafish embryos.

Nodularin (NOD) is a kind of cyanobacterial toxins. It is of concern due to elicit severe genotoxicity in humans and animals. The comprehensive evaluation of NOD-induced adverse effects in living organisms is urgently needed. This study is aimed to report the developmental toxicity and molecular mechanism using zebrafish embryos exposed to NOD. The embryonic toxicity induced by NOD is demonstrated by inhibition of embryo hatching, increase in mortality rate, abnormal heart rate, embryonic malformation as well as defects in angiogenesis and common cardinal vein remodeling. NOD triggered a decreased rate of angiogenesis through inhibiting endothelial cells migration. NOD induced embryonic cell apoptosis and DNA damage, which can be alleviated by antioxidant N-acetyl-L-cysteine. NOD significantly caused oxidative damage as indicated by changes in reactive oxygen species, superoxide dismutase, catalase, glutathione and malondialdehyde. NOD also altered the expression of vascular development-genes (DLL4, CDH5, VEGFA, VEGFC) and apoptosis-related genes (BAX, BCL-2, P53, CASPASE 3). Taken together, NOD induced adverse effect on zebrafish embryos development, which may be associated with oxidative stress and apoptosis through the activation of P53-BAX/BCL-2-CASPASE 3-mediated pathway.

Evaluation of particle shape, size and magnetic field intensity for targeted delivery efficiency and plaque injury in treating atherosclerosis

A comprehensive evaluation of therapeutic effects of magnetic nanoparticle therapy for patient-specific atherosclerosis is presented in terms of targeted delivery efficiency (η) and plaque injury. Eulerian-Lagrangian technique is adopted, and an innovative model is first introduced for simulating targeted delivery drug-loaded particles to plaque, in which the shape and size of particles are taken into account in the drag coefficient CD. The impacts of particle shape, size and magnetic field intensity on η and plaque injury characterized by temporal-spatial averaged shear stress (TAWSS¯) are investigated. The results signify that, among drug delivery using the transport particles of different shapes, the sequences of η and TAWSS¯ are platelet>cylinder>blade>sphere>brick, which indicates that the particle with higher drug targeting ability may induce greater plaque injury. Moreover, it is found that increasing the particle size from 300 to 500 nm or the current from 5E4 to 2E5 A enhances η by nearly 9.3% or 18.1%, respectively, but behind this are greater damage to plaque itself. Along with this, the injury discrepancy of plaque induced by particles with different shapes is also amplified. Results obtained can potentially serve as the guideline to optimize the design of transport particle and magnetic field for targeted therapy to atherosclerosis.

An Evaluation Method of Dynamic Camouflage Effect Based on Multifeature Constraints

Most of the existing camouflage effect evaluation methods are for static images, and the evaluation methods have problems of singularity and subjectivity. Therefore, this paper takes the camouflage of moving objects in video as the research object and proposes a comprehensive camouflage effect evaluation method based on multifeature constraints. This method has two parts: the Homo-F (homography transformation and optical flow) target detection module and the camouflage effect evaluation module. The former uses the optical flow method to correct the target detection results obtained by the homography transformation. The latter performs statistical analysis on the target detection results and the feature information of the neighborhood background and describes the effect of camouflage from multiple angles such as the degree of target fusion, the repetition rate and the target detection stability in the video sequence. The experimental results of the comprehensive camouflage evaluation of moving targets show that the proposed method can objectively and accurately evaluate moving targets with different levels of camouflage, which verifies the reliability and effectiveness of the method.

Comprehensive Evaluation of Effect of Low Dose Local Steroid Injection in Carpal Tunnel Syndrome

Comprehensive Evaluation of Effect of Low Dose Local Steroid Injection in Carpal Tunnel Syndrome