Abstract The resonant behavior of one-way Lamb and SH (shear horizontal) mixing method in composite laminates with transverse-isotropic quadratic nonlinearity is investigated through numerical simulations in this paper. Different from previous studies, the composite constitutive model is combined from orthotropic elasticity and transverse-isotropic quadratic nonlinearity, which is implemented by ABAQUS/VUMAT subroutine. When two fundamental waves (S 0-mode Lamb waves and SH 0 waves) mix in composite laminates with quadratic nonlinearity, the resonant SH 0 waves can be generated with the resonance condition ω S 0 /ω SH 0 = 2 κ/(κ + 1). Meanwhile, the relationships between the acoustic nonlinear parameter (ANP) and damage degree, fundamental frequency, frequency deviation, propagation distance are also investigated. Moreover, the method of locating the damage region in composite laminates is proposed and verified by using the resonant wave time-domain signal.