Complications Of Enteral Nutrition Research Articles

The complications of enteral nutrition in medical wards

The effects of Enteral Nutrition (EN) in patients unable to feed themselves have been widely explored although studies in low-/mean- intensity words are lacking. To measure the prevalence of EN side effects in medical wards and to explore their risk factors. Metodi. Observational, retrospective study on matched patients. All patients in the medical departments of the Azienda Ospedaliero-Universitaria Senese were enrolled (81 cases and 162 controls) from 1 August 2018 to 1 September 2019, aged over 50 years and hospitalized for longer than 4 days. The NE side effects such as diarrhea, vomiting, gastric stagnation and abdominal pain were collected from clinical records The presence of EN, age of patients, mobilization and use of antibiotics during hospitalization were considered risk factors. The prevalence of diarrhea, vomiting, gastric and abdominal pain ranged from 4.9% to 11.1%. The EN was not a significant risk factor for the onset of gastrointestinal disorders, and these complications were always lower than in the controls. Vomiting, diarrhea and abdominal pain were more frequently, though not significantly, associated to antibiotic treatments; the age of subjects significantly predicted the diarrhea, showing a protective effect with the age increase. The study shows a low prevalence of diarrhoea, vomiting and abdominal pain compared to the literature. These symptoms were not significantly associated to the EN, that cannot be considered a risk factor.

A prediction model of enteral nutrition complicated with severe diarrhea in ICU patients based on CD55.

Severe diarrhea is a common complication of enteral nutrition in intensive care unit (ICU) patients. CD55 not only plays a vital role in immune but also plays a crucial role in intestinal function. We intended to build a prediction model of enteral nutrition complicated with severe diarrhea in ICU patients based on CD55. This was a prospective, single-center, observational study. We collected 116 patients with enteral nutrition in the ICU. We collected blood samples from patients at the time of admission, tested blood biomarkers [CD55, interleukin-10 (IL-10), diamine oxidase, D-lactic acid and endotoxin], and recorded daily defecation and enteral nutrition. Finally, through multi-factor logistic regression model, a prediction model based on multiple prediction indicators was formed, and new joint predictive factors were calculated. The prediction model of enteral nutrition complicated with severe diarrhea in ICU patients was constructed through data processing analysis. A total of 116 adult patients with enteral nutrition were divided into two groups: 77 patients without severe diarrhea and 39 with severe diarrhea. Compared with patients without severe diarrhea, CD55 on granulocyte membrane surface(gCD55) of patients with severe diarrhea was significantly reduced (P<0.0001), and CD55 on erythrocyte membrane surface(eCD55) of patients with diarrhea was significantly reduced (P<0.0001), serum IL-10 in patients with diarrhea significantly decreased compared with those without diarrhea, P<0.0001.The area under the curve of receiver operating characteristic (AUCROC) was 0.919 in gCD55 predicting severe diarrhea, when cutoff value =99.95%, the optimal sensitivity was 96.2%, and specificity was 100%. The AUROC of eCD55 and IL-10 in predicting severe diarrhea was 0.658 and 0.558 respectively. Based on this, a prediction model was established. The prediction model was: In[P/(1- P)] =-24.68 gCD55 -2.26 eCD55 +0.0041 IL-10 +2,691, the goodness of fit test of the model was P=0.44, and the AUCROC of the model was 0.92. gCD55 and eCD55 had certain predictive value in enteral nutrition complicated with severe diarrhea.

The prevalence and possible causes of enteral tube feeding intolerance in critically ill patients: A cross-sectional study.

Background:Enteral tube feeding intolerance (ETFI) is one of the most common complications of enteral nutrition (EN), which may lead to increased mortality and length of intensive care unit (ICU) stay. This study aimed to determine the prevalence of ETFI and effects on feeding intolerance on nutrition and clinical outcomes in Iran.Materials and Methods:This cross-sectional study was conducted in 2019 at the three general ICUs of Imam Reza Hospital in Mashhad, Iran, during 7 days on 245 patients. The collected data included demographic characteristics, primary diagnosis, the Acute Physiology and Chronic Health Evaluation II (APACHE ІІ) score, Sequential Organ Failure Assessment (SOFA) score, duration of mechanical ventilation, and length of ICU stay. Feeding intolerance was assessed using daily questionnaires for 7 days. ETFI was determined as the interruption of EN based on gastrointestinal causes, including large gastric residuals, abdominal distension, vomiting, diarrhea, and subjective discomfort.Results:Overall, 245 critically ill patients (122 males and 123 females) were included in this study, with a mean age of 58.43 ± 19.2 years in three general ICUs. The highest prevalence rate of ETFI was 91.8%, which occurred on the 2nd day although the rate decreased in the following days. The minimum ETFI was observed on the last day (38.8%). Feeding intolerance was associated with the increased APACHE II scores (P = 0.04), SOFA scores (P < 0.001), and duration of mechanical ventilation (P < 0.001) compared with the tolerant patients. The most common causes of ETFI in the patients admitted to the ICU were gastric residual volume (GRV), large GRV, vomiting, and distension.Conclusion:ETFI was prevalent in almost two-third (66%) of the critically ill patients receiving EN based on the GRV. ETFI was associated with deteriorated nutritional status and clinical outcomes.

Effects of an Enteral Formula Containing Fermented Dairy Products on Epithelial Ion Transport in Rat Intestines.

Diarrhea is the most common complication of enteral nutrition (EN). Pro/prebiotics are typically used to prevent diarrhea during EN. This study aimed to demonstrate the effects of enteral formula containing fermented dairy products (FDPs) and galacto-oligosaccharides on intestinal mucosal functions in rats. After feeding rats with regular rodent chow (RRC), standard formula (STD-F), and FDP-containing formula (FDP-F) for 2 wk, the rats were sacrificed with their intestines removed. Then, the electrophysiological properties of intestinal epithelia were measured using the Ussing chamber. In addition, organic acids and microbiota in the cecal contents were analyzed. In FDP-F-fed rats, electrical nerve activation-evoked increase in short-circuit current (Isc) in the cecum and middle colon was reduced compared with STD-F-fed rats. Mucosal propionate-evoked changes in Isc in FDP-F-fed rats were also reduced in the terminal ileum. The total cecal organic acid concentration in STD-F-fed rats decreased compared with RRC-fed rats, and approximately half was recovered in FDP-F-fed rats, which contributed to the recovery of acetate and butyrate concentrations. In microbiota analysis, the density of total bacteria, particularly Bifidobacterium, in cecal contents increased in FDP-F-fed rats. In conclusion, the consumption of FDP-F changed the total amounts and components of gut microbiota and organic acids, and resulted in inhibitory changes in mucosal luminal stimulant- and nervous system-mediated fluid secretory function. These findings suggest that FDP-F might prevent the incidence of diarrhea during EN.

Effect of standardized process management of early enteral nutrition after operation on rapid recovery of elderly patients with gastric cancer

Objective To explore the clinical effect of applying standard process management in early enteral nutrition support for elderly patients with gastric cancer after operation. Methods A total of 142 elderly patients with gastric cancer in our hospital were randomly divided into control group(n=71) treated with the traditional nursing of enteral nutrition and intervention group(n=71) adopting the standardized process management, and then enteral nutrition tolerance, complications, nutritional status and recovery of gastrointestinal function were compared between the two groups. Results There was no significant difference in age, sex and preoperative nutritional condition and operation situation between the two groups(P>0.05). The incidence of nutritional intolerance and the cost of nutritional support were lower than those in the control group(P 0.05) . Conclusions Standardized process management of early enteral nutrition after operation could significantly improve the tolerance of enteral nutrition, meanwhile, it has positive significance in promoting rapid recovery of elderly patients with gastric cancer. Key words: Standardization; Enteral nutrition; Elderly; Gastric cancer

Application of FOCUS-PDCA model in nasointestinal enteral nutrition in severe neurological patients

Objective To explore the application of FOCUS-PDCA model in nasointestinal enteral nutrition in severe neurological patients. Methods Patients admitted to the neurological intensive care unit of the hospital were selected as the study subjects. 53 patients admitted from January 2017 to December 2017 were the control group, and 78 patients admitted from January 2018 to December 2018 were the observation group.The control group adopted conventional nasointestinal enteral nutrition support, while the observation group applied FOCUS-PDCA model to find out the weak links of nasointestinal tube placement and nutrition support in clinical nursing for patients with severe neurological diseases, analyze the reasons, formulate rectification measures, formulate standardized procedures and standardize nursing.The time, success rate, incidence of enteral nutrition complications, nutritional index and clinical outcome of the two groups were compared. Results The incidence of complications such as aspiration, diarrhea and reflux in the observation group was lower than that in the control group, and the differences were statistically significant (P<0.05). Serum albumin and hemoglobin in the observation group were significantly higher than those in the control group.The success rate of blind insertion increased from 56.00% in 2017 to 93.30% in 2018.The average length of tube placement decreased from 168 minutes in 2017 to 23 minutes in 2018.There were statistically significant differences between the two groups in terms of ICU stay days and hospitalization costs(P<0.05). Conclusions The application of FOCUS-PDCA model can shorten the time of nasointestinal catheterization, improve the success rate of catheterization, reduce the occurrence of enteral nutrition complications in patients with severe neurological diseases, and facilitate enteral nutrition supply and benign outcome of patients with severe neurological diseases. Key words: FOCUS-PDCA model; Neurological intensive; Nasointestinal tube; Nasojejunal tube feeding (NJF)

Application of enteral nutrition feeding procedure in severe patients in ICU

Objective To investigate the effect of enteral nutrition feeding procedure in ICU in severe patients in order to reduce complications and promote rehabilitation of patients. Methods A total of 184 severe patients admitted to ICU from January to October 2018 were selected as the subjects of the study. 90 patients admitted to the family from January to May were the control group, and 94 patients admitted to the family from June to October were the observation group. The control group adopted routine nutritional support and nursing, and the observation group carried out intensive enteral nutrition feeding process. The nutritional status, immunity, gastrointestinal dysfunction, complications of nosocomial infection and outcome of patients in two groups were compared between the two groups. Results The nutritional indicators of hemoglobin, serum total protein and serum albumin after a week of treatment were (119.73 ± 9.96), (58.88 ± 2.65), (29.09 ± 1.42) g/L, immunization indicators IgA, IgG, IgM were (2.56±0.10), (2.98±0.36), (1.65±0.15) g/L in the observation group. The control groups were (108.02±9.21), (51.90±2.74), (27.80±1.59), (2.09±0.18), (2.01±0.24), (1.41±0.13)g/L, the difference between the two groups was statistically significant (t=5.81-22.48, P<0.01). The incidence of gastrointestinal dysfunction (gastric retention, diarrhea) in the observation group were 11.70%(11/94), 8.51%(8/94), the incidence of nosocomial infections (ventilator associated pneumonia, catheter related blood stream infection, catheter-associated urinary tract infections) were 6.12‰(5/817), 1.53‰(1/650), 0, the outcome indicators of patients (nutritional standard time, ICU hospitalization time, and mortality rate) were (6.12±1.03) d, (10.98±2.03) d, 13.82%(13/94), all were lower than the control group′s 23.33%(21/90), 20.00%(18/90), 13.06‰(11/842), 11.28‰(8/709), 2.88 ‰(2/694), (7.98 ± 1.54) d, (12.21 ± 1.87) d, 26.67%(24/90), the difference between the two groups was statistically significant (χ2=4.33-8.22, t=6.19, 2.26, P<0.05). Conclusions The procedure of enteral nutrition feeding in patients with severe illness can effectively reduce enteral nutrition complications and enable patients to obtain effective nutrition early. Key words: Severe patients; Enteral nutrition; Feeding process

Application effect of nasointestinal tube in patients with high risk of stroke aspiration by mistake

Objective To investigate the effect of nasointestinal tube in patients with high risk of stroke aspiration. Methods A total of 61 patients with high risk of stroke aspiration by mistake who were hospitalized in the department of neurology in the first district of the hospital from March to December 2017 were selected and divided into the control group (40 cases) and the observation group (21 cases) by random number table method.The control group received enteral nutrition support by nasogastric tube, and the observation group received enteral nutrition support by nasointestinal tube.The incidence of enteral nutritional complications, nutritional status indicators, immune function indicators, Glasgow coma index (GCS) score, neurological deficit (NIHSS) score, mechanical ventilation time, ICU treatment time, and mortality at 30 days were compared between the two groups. Results The total incidence of enteral nutrition complications in the observation group was lower than that in the control group (P<0.05). After treatment, the nutritional status indexes of hemoglobin, albumin and transferrin in both groups were significantly higher than before treatment (P< 0.05), while the nutritional status indexes of the observation group were higher than those of the control group (P< 0.05). After treatment, CD3+ , CD4/CD8 and other immune function indicators in both groups were significantly higher than those before treatment (P< 0.05), while the immune function indexes in observation group were higher than that of control group (P< 0.05). After treatment, GCS scores in both groups were higher than before treatment (P<0.05), while the GCS score in the observation group was higher than that in the control group (P<0.05). After treatment, NIHSS scores of both groups were lower than before treatment (P<0.05), while the NIHSS score in the observation group was lower than that in the control group (P<0.05). Mechanical ventilation time and ICU treatment time in the observation group were significantly shorter than those in the control group (P<0.05). There was no statistically significant difference in the case fatality rate between the two groups on 30 days (P<0.05). Conclusions The application of nasointestinal nutrition therapy in patients with high risk of stroke aspiration by accident can effectively reduce the occurrence of complications such as aspiration by accident and reflux, which is conducive to improving the nutritional status, immune function, consciousness state and neurological function of patients, shortening the treatment time, reducing the mortality and improving the prognosis. Key words: Stroke; Aspiration by mistake; Enteral nutrition; Nasointestinal tube

Effects of enteral nutrition program based on intensive ultrasound monitoring gastric residual on patients receiving lung transplantation

Objective To explore the effects of enteral nutrition program based on intensive ultrasound monitoring gastric residual on patients receiving lung transplantation. Methods Totally 100 patients who received lung transplantation in a Class Ⅲ Grade A hospital between January and December 2016 were selected and divided into the treatment group (n=50) and the control group (n=50) according to the random number table. Patients in the treatment group received enteral nutrition based on intensive ultrasound monitoring gastric residual, while patients in the control group received conventional enteral nutrition. The indicators of enteral nutrition application and complications were observed in both groups. Results The gastric residual of the treatment group was (130.32±40.44) ml; the nutrition interruption rate was 6%; the time for achieving the target feed volume was (3.47±0.62) d, lower than those of the control group (t/χ2=-2.341, 8.575, 2.193; P 0.05) , which was 6%. The incidence rates of enteral nutrition reflux, diarrhea and reintubation rates of the treatment group were 10%, 10% and 8%, respectively, lower than those of the control group (33%, 26%, 24%) (χ2=6.250, 4.336, 4.762; P<0.05) . Conclusions The enteral nutrition program based on intensive ultrasound monitoring gastric residual conforms to target-oriented nursing care for patients receiving lung transplantation, which helps to achieve the target feed volume more quickly and ameliorate enteral nutrition-related complications. Key words: Transplantation, lung; Ultrasound; Enteral nutrition; Gastric residual

Feeding Jejunostomy after esophagectomy cannot be routinely recommended. Analysis of nutritional benefits and catheter-related complications

BackgroundPatients undergoing esophagectomy for cancer usually deal with malnourishment which increases postoperative morbimortality. The objective of this paper is to analyze the nutritional benefits of feeding jejunostomy (FJ) for early postoperative enteral nutrition (EN) and directly-related complications. Material and methodsRetrospective study of 100 patients undergoing esophagectomy for cancer between 2008 and 2016. ResultsFJ was placed in 47 patients. 82.98% reached EN requirements in FJ group, with a median EN re-start of 1.9 days and median days to objective requirements of 5 days.51.06% developed directly-related FJ complication, 91.66% of them mild ones (gastrointestinal or catheter-related). 2 patients (4.25%) required re-intervention.No significant differences were shown in total protein and albumin seric levels during first postoperative week and in anastomotic leak rate between both groups (p > 0.05). ConclusionsFeeding jejunostomies are associated with a great number of complications although most are not life-threatening. Since its nutritional benefit is not proven FJ cannot routinely recommended after esophagectomy. However, the optimal pathway for EN reintroduction, including direct oral intake, is still a matter of debate.

Effects of fiber and probiotics on diarrhea associated with enteral nutrition in gastric cancer patients: A prospective randomized and controlled trial.

Background and objectives:Diarrhea is a common complication of enteral nutrition (EN), which affects recovery and prolongs the length of hospital stay (LOHS). To investigate the effect of fiber and probiotics in reducing diarrhea associated with EN in postoperative patients with gastric cancer (GC), the authors designed this prospective randomized-controlled trial.Methods and study design:This study included 120 patients with GC, and the patients were classified into 3 groups via random picking of envelopes: fiber-free nutrition formula (FF group, n = 40), fiber-enriched nutrition formula (FE group, n = 40), and fiber- and probiotic-enriched nutrition formula (FEP group, n = 40). All patients were given EN formulas for 7 consecutive days after surgery.Results:The number of diarrhea cases was higher in the FF group than in the FE group (P = .007). The FEP group had a lower number of diarrhea cases compared with the FE group (P = .003). Patients in the FE group had a significantly shorter first flatus time than the FF group (P = .002). However, no significant difference was observed between the FE group and FEP group (P = .30). Intestinal disorders were similar between the FE group and FF group (P = .38). The FEP group had a lower number of intestinal disorder cases than the FF group (P = .03). LOHS in the FE and FEP groups was shorter than that in the FF group (P = .004; P < .001). However, no significant difference was observed between the FE and FEP groups (P = .28). In addition, no significant difference was observed between the 3 groups in terms of total lymphocyte count, albumin, prealbumin, and transferrin levels on day 7 of enteral feeding.Conclusions:The combination of fiber and probiotics was significantly effective in treating diarrhea that is associated with EN in postoperative patients with GC.

SUN-P022: Enteral Nutrition Complications in Patients with Heart Disease

SUN-P022: Enteral Nutrition Complications in Patients with Heart Disease

Antibiotic prophylaxis does not reduce the infection rate following percutaneous endoscopic gastrostomy in infants and children.

Percutaneous endoscopic gastrostomy (PEG) is the standard for placing gastrostomy in children needing long-term enteral nutrition, with major and minor complications reported in up to 19% and 47.7% of children, respectively. We reviewed our experience with PEG, concentrating on the efficacy of antibiotic prophylaxis in reducing infectious complications. We performed a retrospective, single-centre study that comprised all children up to 18 years of age who underwent a first PEG procedure in the VU University Medical Centre, Amsterdam, from 2008 to 2012. All complications up to one month after PEG were recorded. Infection rates with and without antibiotic prophylaxis could be compared as a new protocol requiring the preprocedure administration of cefazolin was not followed consistently. We enrolled 129 patients (78 male) with a mean age of 4.9 ± 4.8 years and median age of 2.9 years. Major complications were seen in seven patients (5.4%) and minor complications in 23 patients (17.8%). Antibiotic prophylaxis was administered to 99 of 129 children (76.7%). Infections occurred in 15 of 129 patients (11.6%); 14 of 99 with and 1 of 30 without prophylaxis developed infections (p = 0.106). Peristomal infections were the most frequent complication (10.1%). Percutaneous endoscopic gastrostomy was a safe procedure and antibiotic prophylaxis did not seem to decrease infectious complications.

Effect of omega 3 polyunsaturated fatty acids derived from fish oil in major burn patients: A prospective randomized controlled pilot trial

The burn patient is the clearest example of prolonged inflammatory response. Various nutrients, particularly omega-3 polyunsaturated fatty acids (ω-3 PUFAs), have been demonstrated as attenuating the inflammatory response, and reduce infectious complications. In absence of definitive evidence in major burns the study aimed at investigating the effect particularly on infectious complications of enteral nutrition enriched with ω-3 PUFAs. Prospectively randomized controlled trial. adult patients admitted to intensive care (ICU), burns>15% body surface area (BSA), with inhalation injury requiring mechanical ventilation for≥6 days and enteral nutrition. low-fat (18% energy as fat) modular diet (LF-EN) or identical with 50% of fat as fish oil (FO-EN). Study endpoints: infectious and other complications, length of mechanical ventilation time, mortality. Altogether 92 patients, aged 40 years old and burned 38% BSA were analyzed (45 patients in LF-EN and 47 in FO-EN). Baseline characteristics were similar. Severe sepsis and septic shock together were significantly fewer in FO-EN group, 15% versus 33%, p=0.03, (others infections unchanged). Non-infectious complications were less frequent in group FO-EN, with a significant reduction of high gastric residual volume (33% versus 8.5%: p=0.003). Mechanical ventilation was non-significantly shorter with FO-EN (22 versus 26 days). Mortality did not differ. The inclusion of ω-3 PUFAs in a low fat diet in ICU burned patients was associated with significant clinical benefits compared to a conventional low fat diet, with lower rates of severe sepsis, septic shock and pyloric dysfunction. NCT02189538.

Effects of enteral and total parenteral nutrition on length of stay in intensive care unit in postoperative period

Patients post-operatively followed in intensive care units in are known to have high morbidity and mortality rates. The aim of the present study was to compare the effects of enteral versus total parenteral nutrition for length of ICU stay in postoperative patients. Nutritional support for patients were divided into two groups; enteral nutrition (Group E) total parenteral administered (Group P). Demographic findings, APACHE II score and serum albumin levels were determined in the preoperative period in both groups of patients. In both groups were recorded type of operation and blood transfusion during the operation. Gas, fecal discharge time in the postoperative period, of patients in groups and, postoperative day 7th, serum albumin, and serum C-reactive protein (CRP), length of stay intensive care unit and mortality rates were determined. Abdominal cramps, the tension in the abdomen, nausea and diarrhea in patients in group E were accepted as complications of enteral nutrition. In this study were included group E 89, group P 82 patients. Between groups were similar demographic features, APACHE II score and serum albumin levels. Both groups was not significant difference operation type, operation time and blood transfusion. Postoperative gas discharge and fecal discharge were significantly difference earlier period in Group E (p

Complications related with postoperative enteral nutrition in patients with massive cerebellar infarction

Objective To investigate the complications of different enteral nutrition in patients after surgery for massive cerebellar infarction, so as to guide rational application of enteral nutrition in patients. Methods Forty-nine patients with massive cerebellar infarction were divided into three groups randomly: conventional nasogastric tube feeding group (group A, n=12), nasogastric tube feeding plus gastric motor drug group (group B, n=18), and nasojejunal tube feeding group (group C, n=19). The incidences of diarrhea, reflux, aspiration, upper gastrointestinal bleeding and aspiration pneumonia within 3 weeks after initiation of enteral nutrition were observed and compared among the groups. Results The incidence of diarrhea showed no statistically significant difference among the 3 groups(χ2=0.092, P=0.955). Compared with group A, the incidences of reflux, aspiration and aspiration pneumonia were significantly lower in group B and group C (P<0.05), and lower in group C compared with group B(P<0.05). Compared with group C, the incidence of upper gastrointestinal bleeding was significantly lower in group C than in group A and group B(χ22=4.748, P2=0.029; χ32=4.284, P3=0.038), but the difference between group A and group B was not significant(χ12=0.000, P1=1.000). Conclusions Because of the unique pathophysiological features in patients after surgery for massive cerebellar infarction, early enteral nutrition by conventional nasogastric tube feeding may be inappropriate. Nasogastric tube feeding plus gastric motor drug may be applied in mild case with short course of disease. Nasojejunal tube feeding may be the approach of choice for enteral nutrition in critical patients with massive cerebellar infarction for its association with lower incidence of complications. Key words: Cerebellar infarction; Enteral nutrition; Complication; Nasogastric tube; Nasojejunal tube

Wrośnięty PEG – powikłanie żywienia dojelitowego

Wrośnięty PEG – powikłanie żywienia dojelitowego

Enteral nutrition in pancreaticoduodenectomy: a literature review.

Pancreaticoduodenectomy (PD) is considered the gold standard treatment for periampullory carcinomas. This procedure presents 30%–40% of morbidity. Patients who have undergone pancreaticoduodenectomy often present perioperative malnutrition that is worse in the early postoperative days, affects the process of healing, the intestinal barrier function and the number of postoperative complications. Few studies focus on the relation between enteral nutrition (EN) and postoperative complications. Our aim was to perform a review, including only randomized controlled trial meta-analyses or well-designed studies, of evidence regarding the correlation between EN and main complications and outcomes after pancreaticoduodenectomy, as delayed gastric emptying (DGE), postoperative pancreatic fistula (POPF), postpancreatectomy hemorrhage (PPH), length of stay and infectious complications. Several studies, especially randomized controlled trial have shown that EN does not increase the rate of DGE. EN appeared safe and tolerated for patients after PD, even if it did not reveal any advantages in terms of POPF, PPH, length of stay and infectious complications.

Application of intermittent gravity tube feeding on very low birth weight infants in NICU

Objective To evaluate the effects of intermittent nasogastric feeding on neonatal intensive care unit （ NICU） on very low birth weight infants gastrointestinal complications .Methods Two hundred and fifteen very low birth weight infants were randomly assigned to either observation group （ n=106 ） or the control group （ n=109 ） .Infants in the observation group received intermittent gravity tube feeding .Infants in the control group received continuous drip tube feeding .Weight increase , total parenteral nutrition time , length of stay and complication were assessed .Results Observation group of very low birth weight infants when were turned out of the NICU, weight increased to（1 397.0 ±22.10）g, higher than the control group （1 320.0 ± 18.25）g, was statistically significant difference （t=2.26,P〈0.05）;total parenteral nutrition time, length of stay in NICU were （4.94 ±0.70）,（9.69 ±7.19）d,in observation group, were lower than the control group [（4.74 ±0.74）,（11.63 ±4.02）d], differences were statistically significant （t=2.72,4.85,respectively;P〈0.01）.The incidence of abdominal distention , vomiting, diarrhea, upper gastrointestinal bleeding in observation group were lower than the control group , and had statistical significance （P〈0.05）.However, the very low birth weight infants had not occurred necrotizing enterocolitis in two groups .Conclusions Intermittent nasal tube feeding can reduce the complications of enteral nutrition , shorten the time of hospitalizationand increased body weight growth rate . Key words: Very low birth weight infants; Complications; NICU; Gravity tube feeding

PTH-048 Perception Of Assessing The Nutritional Status Of Intensive Care Patients: A Cross Sectional Study Of Jordanian Icu Nurses

IntroductionEnteral nutrition is a pivotal strategy for nutrition in ICUs (Fulbrook et al. 2007). Nurses are keys to assess patients’ nutritional status, detect feeding-intolerance, and curtail the prospect of complications...