The brief presentation of the method of fast expansions is given to solve nonlinear differential equations. Application rules of the operator of fast expansions are specified for solving differential equations. According to the method of fast expansions, an unknown function can be represented as the sum of the boundary function and Fourier series sines and cosines for one variable. The special construction of the boundary functions leads to reasonably fast convergence of the Fourier series, so that for engineering calculations, it is sufficient to consider only the first three members. The method is applicable both to linear and nonlinear integro-differential systems. By means of applying the method of fast expansions to nonlinear Navier-Stokes equations the problem is reduced to a closed system of ordinary differential equations, which solution doesn't represent special difficulties. We can reapply the method of fast expansions to the resulting system of differential equations and reduce the original problem to a system of algebraic equations. If the problem is n -dimensional, then after n -fold application of the method of fast expansions the problem will be reduced to a closed algebraic system. Finally, we obtain an analytic-form solution of complicated boundary value problem in partial derivatives. The flow of an incompressible viscous fluid of Navier–Stokes is considered in a curvilinear pipe. The problem is reduced to solving a closed system of ordinary differential equations with boundary conditions by the method of fast expansions. The article considers peculiarities of finding the coefficients of boundary functions and Fourier coefficients for the zero-order and first-order operators of fast expansions. Obtaining the analytic-form solution is of great interest, because it allows to analyze and to investigate the influence of various factors on the properties of the viscous fluid in specific cases.