Complex Organic Compounds Research Articles

Continuous Ligand-Free Catalysis Using a Hybrid Polymer Network Support.

Although the pharmaceutical and fine chemical industries primarily utilize batch homogeneous reactions to carry out chemical transformations, emerging platforms seek to improve existing shortcomings by designing effective heterogeneous catalysis systems in continuous flow reactors. In this work, we present a versatile network-supported palladium (Pd) catalyst using a hybrid polymer of poly(methylvinylether-alt-maleic anhydride) and branched polyethyleneimine for intensified continuous flow synthesis of complex organic compounds via heterogeneous Suzuki-Miyaura cross-coupling and nitroarene hydrogenation reactions. The hydrophilicity of the hybrid polymer network facilitates the reagent mass transfer throughout the bulk of the catalyst particles. Through rapid automated exploration of the continuous and discrete parameters, as well as substrate scope screening, we identified optimal hybrid network-supported Pd catalyst composition and process parameters for Suzuki-Miyaura cross-coupling reactions of aryl bromides with steady-state yields up to 92% with a nominal residence time of 20 min. The developed heterogeneous catalytic system exhibits high activity and mechanical stability with no detectable Pd leaching at reaction temperatures up to 95 °C. Additionally, the versatility of the hybrid network-supported Pd catalyst is demonstrated by successfully performing continuous nitroarene hydrogenation with short residence times (<5 min) at room temperature. Room temperature hydrogenation yields of >99% were achieved in under 2 min nominal residence times with no leaching and catalyst deactivation for more than 20 h continuous time on stream. This catalytic system shows its industrial utility with significantly improved reaction yields of challenging substrates and its utility of environmentally-friendly solvent mixtures, high reusability, scalable and cost-effective synthesis, and multi-reaction successes.

ALGAE CAROTENOID PIGMENTS AS NEW SOURCES OF HALAL BIOACTIVE INGREDIENTS

Halal Active Pharmaceutical Ingredient (API) is a substance used in a finished pharmaceutical product, intended to furnish pharmacological activity or contribute direct effect in the diagnosis, cure, mitigation, treatment or prevention of disease. It also provides a direct effect in restoring, correcting or modifying physiological functions in human beings. Microalgae, which are single-celled microorganisms, are considered to be a rich source of diverse bioactive molecules. They play a vital role in the aquatic food chain as primary producers and can store complex organic compounds in their bodies, which can be released with the help of sunlight. Microalgae have evolved distinctive metabolic pathways, resulting in the production of remarkable secondary metabolites and unique structures that differ from those found in superior plants. Due to the high structural diversity of pigments, microalgae have the potential to produce pharmacologically valuable compounds, making them a promising source of bioactive molecules. This study aimed to examine the carotenoids pigmentation profiling from selected microalgae species subjected to different culture conditions. The methods involve are microalgae cell culture mass production, carotenoid sample extraction and HPLC analysis. The findings revealed that the composition and amount of carotenoids differ according to the microalgae species. Genetic factors appear to be a crucial factor in categorizing these species based on their individual carotenoids accumulation. In short, selecting the appropriate species with the ability to accumulate carotenoids is important in determining the sources of pigments for halal bioactive ingredients or for commercial purposes, particularly in the halal market.

Exploring the Potential and Challenges of Electrochemical Processes for Sustainable Waste Water Remediation and Treatment

Emerging as an efficient, cost-effective, and environmentally sound approach, electrochemical treatment methods hold significant promise for sustainable remediation and wastewater treatment. This review elucidates recent progress in electrochemical techniques used for site decontamination and wastewater management. It elucidates the fundamental electrochemical processes, detailing the principles of electrocoagulation, electroflocculation, electrochemical membranes, electrochemical oxidation (EO), and advanced oxidation processes (AOPs). The broad applicability of these methods for contaminant removal, inclusive of heavy metals, organic pollutants, complex organic compounds, and suspended particulate matter, is underscored. Notwithstanding, the adoption of these techniques encounters notable challenges. These involve the heterogeneity of soil conditions, the presence of intricate contaminant mixtures, and the risk of electrode fouling and degradation. Suggestions for overcoming such challenges include refining the comprehension of electrochemical treatment processes in field-scale applications, investigating innovative electrode materials, and developing advanced modeling and simulation tools. This review offers a robust overview of electrochemical treatment strategies for sustainable wastewater management and can guide researchers, engineers, and policymakers towards the successful adoption and implementation of these techniques to meet environmental challenges and foster sustainable water management.

Soil Thermophiles and Their Extracellular Enzymes: A Set of Capabilities Able to Provide Significant Services and Risks.

During this century, a number of reports have described the potential roles of thermophiles in the upper soil layers during high-temperature periods. This study evaluates the capabilities of these microorganisms and proposes some potential consequences and risks associated with the activity of soil thermophiles. They are active in organic matter mineralization, releasing inorganic nutrients (C, S, N, P) that otherwise remain trapped in the organic complexity of soil. To process complex organic compounds in soils, these thermophiles require extracellular enzymes to break down large polymers into simple compounds, which can be incorporated into the cells and processed. Soil thermophiles are able to adapt their extracellular enzyme activities to environmental conditions. These enzymes can present optimum activity under high temperatures and reduced water content. Consequently, these microorganisms have been shown to actively process and decompose substances (including pollutants) under extreme conditions (i.e., desiccation and heat) in soils. While nutrient cycling is a highly beneficial process to maintain soil service quality, progressive warming can lead to excessive activity of soil thermophiles and their extracellular enzymes. If this activity is too high, it may lead to reduction in soil organic matter, nutrient impoverishment and to an increased risk of aridity. This is a clear example of a potential effect of future predicted climate warming directly caused by soil microorganisms with major consequences for our understanding of ecosystem functioning, soil health and the risk of soil aridity.

Leaf litter chemistry and its effects on soil microorganisms in different ages of Zanthoxylum planispinum var. Dintanensis

BackgroundLeaf litter is the products of metabolism during the growth and development of plantation, and it is also an important component of nutrient cycling in plantation ecosystems. However, leaf litter chemistry and its effects on soil microorganisms in different ages, as well as the interactions between chemical components in leaf litter have been rarely reported. Based on this, this paper took Zanthoxylum planispinum var. dintanensis (hereafter Z. planispinum) plantations of 5–7, 10–12, 20–22, and 28–32 years old as the objects. By using one-way ANOVA, Pearson correlation analysis and redundancy analysis, we investigated leaf litter chemistry and its effects on soil microorganisms in different ages, and to reveal internal correlation of various chemical components in leaf litter, which can provide a scientific basis for the regulation of soil microbial activity in plantations.ResultsThe variation of organic carbon with plantation age was more stable compared to total nitrogen and phosphorus of leaf litter. Nitrogen resorption was stronger than phosphorus resorption efficiency in Z. planispinum, and resorption efficiencies of leaf nitrogen and phosphorus for different ages were lower than the global average. Total nitrogen was highly significantly positively correlated with lignin, and total potassium was significantly positively correlated with tannin, suggesting the increase of inorganic substances in leaf litter would promote the accumulation of secondary metabolites. The leaf litter chemical traits explained up to 72% of soil microorganisms, where lignin was positively correlated with fungi and negatively correlated with bacteria, indicating that fungi are able to decompose lower quality litter and can break down complex and stable organic compounds more rapidly than bacteria. The nutrient elements carbon and nitrogen in the leaf litter and their interrelationship also have a great impact on soil microorganisms, because carbon is not only the element that provides energy, but also the element with the largest content in the microbiota.ConclusionsThe sustained increase in inorganic nutrients of leaf litter did not favor the decomposition of secondary metabolites, but rather inhibited the degradation of leaf litter. The significant positive effect of the leaf litter chemistry on soil microorganisms indicates the important role of leaf litter in promoting nutrient cycling in Z. planispinum plantations.

The influence of the addition of Agaricus bisporus to the diet on the volatile profile of lamb meat

The aim of the research was to qualitatively determine volatile aroma compounds in the M. longissimus dorsi of lambs. The research included a total of 30 lamb carcasses divided into three groups. The animals were fed with a regular commercial feed mixture, which was supplemented with chopped dried or fresh common mushrooms (Agaricus bisporus) in various proportions. Volatile compounds were determined using headspace solid-phase microextraction, coupled with gas chromatography/mass spectrometry. The identified compounds are classified into the following chemical groups: aldehydes, esters, alcohols, amino acids, peptides, lactones, ketones, fatty acids, complex organic compounds, ethers and furans. Further research is needed to determine whether the differences between the groups in the volatile compounds identified affect the acceptability of lamb meat to consumers.

Selenium Organic Content Prediction in Jengkol (Archidendron pauciflorum) and Its Molecular Interaction with Cardioprotection Receptors PPAR-γ, NF-κB, and PI3K.

Selenium (Se) is a trace mineral found in plants with a distinct sulfuric odor that is cardioprotective and reported to have low toxicity. West Java, Indonesia, has a variety of plants with a distinct odor that are consumed raw, such as jengkol (Archidendron pauciflorum). This study is conducted to determine the Se content of jengkol using the fluorometric method, where the jengkol extract is separated, and the Se content is detected using high-pressure liquid chromatography (HPLC), combined with fluorometry. Two fractions with the highest Se concentration (A and B) are found and characterized using liquid chromatography mass spectrometry to predict the organic Se content by comparing the results with those in the external literature. The Se content of fraction (A) is found to be selenomethionine (m/z 198), gamma glutamyl-methyl-selenocysteine-(GluMetSeCys; m/z 313), and the Se-sulfur (S) conjugate of cysteine-selenoglutathione (m/z 475). Furthermore, these compounds are docked on receptors involved in cardioprotection. The receptors are peroxisome proliferator-activated receptor-γ (PPAR-γ), nuclear factor kappa-B (NF-κB), and phosphoinositide 3-kinase (PI3K/AKT). The interaction of receptor and ligan that has the lowest binding energy of the docking simulation is measured with molecular dynamic simulation. MD is performed to observe bond stability and conformation based on root mean square deviation, root mean square fluctuation, radius gyration, and MM-PBSA parameters. The results of the MD simulation show that the stability of the complex organic Se compounds tested with the receptors is lower than that of the native ligand, while the binding energy is lower than that of the native ligand based on the MM-PSBA parameter. This indicates that the predicted organic Se in jengkol, i.e., gamma-GluMetSeCys to PPAR-γ, gamma-GluMetSeCys AKT/PI3K, and Se-S conjugate of cysteine-selenoglutathione to NF-κB, has the best interaction results and provides a cardioprotection effect, compared to the molecular interaction of the test ligands with the receptors.

Arbuscular mycorrhizas accelerate the degradation of colour containing organic pollutants present in distillery spent wash leachates

Distillery spent wash (DSW) from molasses-based distilleries is being used as a low-cost alternative to chemical fertilizers in countries like India and Brazil. However, using DSW as a fertilizer substitute causes organic pollutant leaching, including melanoidins and caramel colourants that turn bodies of water dark brown. This study investigated the arbuscular mycorrhiza (AM) mediated degradation of organic pollutants in DSW.Mycorrhizal and non-mycorrhizal Sorghum bicolor were grown in microcosms for 16 weeks. The plants were fertilized with either raw DSW or Hoagland solution. Leachates draining from the microcosms after fertilization were collected three times in 30-day intervals. Each 30-day collection was preceded by two fertilizations. A gas chromatography-mass spectrometry comparative analyses of raw DSW with leachates of the third collection from mycorrhizal and non-mycorrhizal microcosms was made. Sixty-five and 42 complex organic compounds were detected in raw DSW and leachate collected from the non-mycorrhizal pots respectively. Only 26 compounds were detected in leachate collected from mycorrhizal pots. Absent from leachate of the mycorrhizal pots were: colour-containing organic compounds diacetone alcohol; 3-amino-2-cyano-6-methyl-6,7-dihydrothieno[2,3-b]pyrazine S-oxide; cyclohexane; 1,2-benzenedicarboxylic acid, butyl 8-methylnonyl ester; 2-pyrrolidinone; and acetic acid, dodecyl ester present in raw DSW. The results indicate that AM fungi can degrade organic pollutants in DSW.

Carbon, iron, and polymer-based conductive materials for improving methane production in anaerobic wastewater treatment systems: A review on their direct interspecific electron transfer mechanism

Organic compounds in wastewater have a high potential to be converted to (bio)methane (CH4) via anaerobic processes for energy recovery. Facilitating direct interspecies electron transfer (DIET) between microorganisms with the addition of conductive materials, as opposed to the conventional anaerobic biological process, has been viewed as an efficient strategy for boosting the efficiency of CH4 production. In recent years, extensive research has been conducted on the performance, mechanisms, and technical uses of conductive materials, such as carbon, iron and polymer-based materials in anaerobic wastewater treatment systems. In this review, the properties of conductive materials have been comprehensively reviewed and summarized, along with their application strategies to enhance CH4 production. In addition, the paper focuses on the methane production mechanism in anaerobic bioreactors, in the presence of carbon, iron, and polymer-based materials. The DIET theory employed for methane synthesis and the involvement of various organic wastes including ethanol, butyrate, propionate, and complex organic compounds are also elaborated upon. The prospective future research directions were also identified and stated in this review.

Elucidating Structures of Complex Organic Compounds Using a Machine Learning Model Based on the 13C NMR Chemical Shifts

We present a protocol that combines the support vector machine (SVM) model with accurate 13C chemical shift calculations at the xOPBE/6-311+G(2d,p) level of theory, denoted as SVM-M (i.e., SVM for magnetic property). We show here that this SVM-M protocol is a versatile tool for identifying the structural and stereochemical assignment of complex organic compounds with high confidence. Of particular significance is that, by utilizing the dual role of the decision values in SVM, the present SVM-M protocol provides an accurate yet efficient solution to simultaneously handle the classification issue (i.e., “is a given structure correct or incorrect?”) and the comparison-based problem (i.e., “which structure is more likely to be correct or wrong among several candidate structures?”). A significantly high success rate has been reached (i.e., ∼100% on a set of 760 sample molecules with 15928 13C chemical shifts), which makes the SVM-M protocol a powerful tool for routine applications in structural and stereochemical assignments, as well as in detecting mis-assignments, for complex organic compounds, including natural products.

Speed of Sound Measurements in Dense Siloxane D6 Vapor at Temperatures up to 645 K by Means of a New Prismatic Acoustic Resonator.

Estimating the speed of sound for the dense vapor phase of D6 (dodecamethylcyclohexasiloxane, C12H36O6Si6) is particularly relevant to the study of nonideal compressible fluid dynamics (NICFD), the gas dynamics of fluids whose properties depart significantly from those related by the ideal gas model. If molecular complexity is sufficiently large, dense vapor flows may exhibit so-called nonclassical gasdynamic effects, and D6 is a candidate for experimental studies aimed at proving for the first time the existence of these exotic phenomena. More in general, speed of sound measurements in the dense vapor phase are important for NICFD applications: for example, complex organic compounds are employed as working fluids in organic Rankine cycle power plants and the correct prediction of the dense-vapor speed of sound is of paramount importance for the design of the supersonic turbines equipping these systems. This type of measurements is challenging and thus rare, especially in the case of complex organic molecules, given the high temperature at which they must be performed, close to the temperature at which the molecule thermally decomposes. Therefore, a new prismatic resonator (the OVAR, organic vapor acoustic resonator) has been conceived, designed, and realized. It is suitable for speed of sound measurements in the vapor phase of organic compounds at temperatures up to approximately 670 K and pressures up to about 1.5 MPa. The speed of sound of D6 (97.4% pure) has been measured along eight isotherms between 555 and 645 K and from nearly saturated density to densities close to ideal gas conditions (compressibility factor Z ≈ 0.95). The estimated relative uncertainty of these sound speed measurements is 0.14%. In addition, corresponding density values have been obtained with an estimated uncertainty between 0.2 kg·m-3 and 1.2 kg·m-3.

Microalgal-induced remediation of wastewaters loaded with organic and inorganic pollutants: An overview

The recent surge in industrialization has intensified the accumulation of various types of organic and inorganic pollutants due to the illegal dumping of partially and/or untreated wastewater effluents in the environment. The pollutants emitted by several industries pose serious risk to the environment, animals and human beings. Management and diminution of these hazardous organic pollutants have become an incipient research interest. Traditional physiochemical methods are energy intensive and produce secondary pollutants. So, bioremediation via microalgae has appeared to be an eco-friendly and sustainable technique to curb the adverse effects of organic and inorganic contaminants because microalgae can degrade complex organic compounds and convert them into simpler and non-toxic substances without the release of secondary pollutants. Even some of the organic pollutants can be exploited by microalgae as a source of carbon in mixotrophic cultivation. Literature survey has revealed that use of the latest modification techniques for microalgae such as immobilization (on alginate, carrageena and agar), pigment-extraction, and pretreatment (with acids) have enhaced their bioremedial potential. Moreover, microalgal components i.e., biopolymers and extracellular polymeric substances (EPS) can potentially be exploited in the biosorption of pollutants. Though bioremediation of wastewaters by microalgae is quite well-studied realm but some aspects like structural and functional responses of microalgae toward pollutant derivatives/by-products (formed during biodegradation), use of genetic engineering to improve the tolerance of microalgae against higher concentrations of polluatans, and harvesting cost reduction, and monitoring of parameters at large-scale still need more focus. This review discusses the accumulation of different types of pollutants into the environment through various sources and the mechanisms used by microalgae to degrade commonly occurring organic and inorganic pollutants.

Microbial ecology of vertebrate decomposition in terrestrial ecosystems.

Vertebrate decomposition results in an ephemeral disturbance of the surrounding environment. Microbial decomposers are recognized as key players in the breakdown of complex organic compounds, controlling carbon and nutrient fate in the ecosystem and potentially serving as indicators of time since death for forensic applications. As a result, there has been increasing attention on documenting the microbial communities associated with vertebrate decomposition, or the 'necrobiome'. These necrobiome studies differ in the vertebrate species, microhabitats (e.g. skin vs. soil), and geographic locations studied, but many are narrowly focused on the forensic application of microbial data, missing the larger opportunity to understand the ecology of these communities. To further our understanding of microbial dynamics during vertebrate decomposition and identify knowledge gaps, there is a need to assess the current works from an ecological systems perspective. In this review, we examine recent work pertaining to microbial community dynamics and succession during vertebrate (human and other mammals) decomposition in terrestrial ecosystems, through the lens of a microbial succession ecological framework. From this perspective, we describe three major microbial microhabitats (internal, external, and soil) in terms of their unique successional trajectories and identify three major knowledge gaps that remain to be addressed.

Transition-metal catalyzed C-H activation as a means of synthesizing complex natural products.

Over the past few decades, the advent of C-H activation has led to a rethink among chemists about the synthetic strategies employed for multi-step transformations. Indeed, deploying innovative and masterful tricks against the numerous classical organic transformations has been the need of the hour. Despite this, the immense importance of C-H activation remains unfulfilled unless the methodology can be deployed for large-scale industrial processes and towards the concise, step-economic synthesis of prodigious natural products and pharmaceutical drugs. Lately, the growing potential of C-H activation methodology has indeed driven the pioneers of synthetic organic chemists into finding more efficient methods to accelerate the synthesis of such complex molecular scaffolds. This review aims to draw a general overview of the various C-H activation procedures that have been adopted for synthesizing these vast majority of structurally complicated natural products. Our objective lies in drawing a complete picture and taking the readers through the synthesis of a series of such complex organic compounds by simplified techniques, making it step-economic on a larger scale and thus instigating the readers to trigger the use of such methodology and uncover new, unique patterns for future synthesis of such natural products.

SYNTHESIS OF SOL-GEL SILICA: OPTIMIZATION OF SUPPORTS FOR CATALYSTS USING ORANGE BIO-RESIDUES

Citrus bio-residues play an important role in obtaining different materials through the sol-gel method. This method is a friendly technique. These waste consists of organic compounds with a wide variety and chemical reactivity. In this way, it has been recognized that this kind of waste, generated mostly by the food industry, has an important potential to obtain silica to be used as a catalyst support. Provided that the principles of green chemistry and circular economy are present. This work aims to use the peel and juice of orange bio-residues, in acidic hydrolysis to obtain sol-gel silica. FT-IR spectra confirm silica formation according to the centered band at 1070 cm-1. In addition, SEM and TEM images of the synthesized materials were compared to a reference sample to contrast their morphology. Strictly speaking, orange bio-residues promote silica polymerization, due to the availability of complex organic compounds and their abundant acidic contribution.

Antagonistic activity of pigment-forming streptomycets isolated from various anthropogenic zones of Tashkent, Uzbekistan

Actinomycetes play an important role in soil formation and soil fertility. Improvement of soils is connected with their activity. they transform and destroy complex organic compounds (cellulose, chitin, lignin, and others) that are inaccessible to many other microorganisms. Actinomycetes are of the greatest interest for biotechnology as producers of antibiotic substances. Antagonistic activity to phytopathogens of local strains of pigment-forming actinomycetes of the genus Streptomyces isolated from various anthropogenic zones of Tashkent was shown. Active strains with high antagonistic activity to plant pathogens were selected. The results showed that the significant was the antagonistic effect of Streptomyces sp.15 to the studied phytopathogens, while the zone of no growth of pathogens reached from 22 mm to 26 mm.

Modern methods for the determination of pesticide residues in beekeeping products and for the diagnostics of bee poisoning

Intensification of agricultural production is associated with the use of a significant amount of pesticides, which negatively affects the environment and human health, and food products, including beekeeping products, accordingly require mandatory control of residual amounts of pesticides. This article provides a comparative analysis of the available chromatographic methods for pesticide residue research. The necessity of using modern chromatographic methods to determine residual amounts of pesticides in samples of dead bees and beekeeping products is well-founded. Chromatographic methods of studying these indicators in different types of matrices are a priority. They are effective methods of analysis, widely used due to their versatility - they allow the analysis of complex inorganic and organic compounds in various aggregate states. But one of the most common modern methods for pesticide determination is gas and liquid three-quadrupole tandem chromatography-mass spectrometry (GC and/or LC-MS/MS). The GC-MS/MS method provides quantitative determination of analytes at a level that is an order of magnitude higher than, for example, the gas single quadrupole mass spectrometry method. Modern methods of gas and liquid chromatography in combination with quadrupoletime-of-flight mass spectrometric detection (LC/Q-TOF/MS or GC/ Q-TOF/MS) also allow qualitative and quantitative multicomponent analysis of pesticides in beekeeping products. GC and LC systems combined with high-resolution Orbitrap MS (GC-HRMS(Q-Orbitrap)/LC-HRMS (Q-Orbitrap)) have higher sensitivity, enabling ultra-trace detection, and are the most sensitive screening method for multicomponent determination of pesticide residues. Thus, the latest chromatographic methods are able to meet the needs of analytical testing and research laboratories in the field of food safety, including beekeeping products. Key words: chromatographic methods, thin-layer chromatography, gas chromatography, liquid chromatography, mass spectrometry, multi-component analysis, pesticides, honey, dead bees.

Unified Modeling Approach for Quantifying the Proton and Metal Binding Ability of Soil Dissolved Organic Matter.

Soil dissolved organic matter (DOM) is composed of a mass of complex organic compounds in soil solutions and significantly affects a range of (bio)geochemical processes in soil environment. However, how the chemical complexity (i.e., heterogeneity and chemodiversity) of soil DOM molecules affects their proton and metal binding ability remains unclear, which limits our ability for predicting the environmental behavior of DOM and metals. In this study, we developed a unified modeling approach for quantifying the proton and metal binding ability of soil DOM based on Cu titration experiments, Fourier transform ion cyclotron resonance mass spectrometry data, and molecular modeling method. Although soil DOM samples from different regions have enormously heterogeneous and diverse properties, we found that the molecules of soil DOM can be divided into three representative groups according to their Cu binding capacity. Based on the molecular models for individual molecular groups and the relative contributions of each group in each soil DOM, we were able to further develop molecular models for all soil DOM to predict their molecular properties and proton and metal binding ability. Our results will help to develop mechanistic models for predicting the reactivity of soil DOM from various sources.

Selection and Analytical Performances of the Dragonfly Mass Spectrometer Gas Chromatographic Columns to Support the Search for Organic Molecules of Astrobiological Interest on Titan.

Titan is a key planetary body for astrobiology, with the presence of a subsurface ocean and a dense atmosphere, in which complex chemistry is known to occur. Approximately 1-Titan-year after the Cassini-Huygens mission arrived in the saturnian system, Dragonfly rotorcraft will land on Titan's surface by 2034 for an exhaustive geophysical and chemical investigation of the Shangri-La organic sand sea region. Among the four instruments onboard Dragonfly, the Dragonfly Mass Spectrometer (DraMS) is dedicated to analyze the chemical composition of surface samples and noble gases in the atmosphere. One of the DraMS analysis modes, the Gas Chromatograph-Mass Spectrometer (GC-MS), is devoted to the detection and identification of organic molecules that could be involved in the development of a prebiotic chemistry or even representative of traces of past or present life. Therefore, DraMS-GC subsystem should be optimized to detect and identify relevant organic compounds to meet this objective. This work is focused on the experimental methods employed to select the chromatographic column to be integrated in DraMS-GC, to assess the analytical performances of the column selected, and also to assess the performances of the second DraMS-GC column, which is devoted to the separation of organic enantiomers. Four different stationary phases have been tested to select the most relevant one for the separation of the targeted chemical species. The results show that the stationary phase composed of polymethyl (95%) diphenyl (5%) siloxane is the best compromise in terms of efficiency, robustness, and retention times of the molecules. The combination of the general and the chiral columns in DraMS is perfectly suited to in situ chemical analysis on Titan and for the detection of expected diverse and complex organic compounds.

Optimization of Photo-electrochemical Treatments for the Degradation of Complex Organic Compounds and Prediction of Degradation via Artificial Neural Networks

Optimization of Photo-electrochemical Treatments for the Degradation of Complex Organic Compounds and Prediction of Degradation via Artificial Neural Networks