Complex Blast Research Articles

Combat-related peripheral nerve injuries.

Active-duty service members (ADSM) and military Veterans represent a population with increased occupational risk for nerve injuries sustained both during training operations and wartime. Mechanisms of war-related nerve injuries have evolved over time, from the musket ball-related traumas described by S.W. Mitchell to complex blast injuries and toxic exposures sustained during Middle East conflicts in the 21st century. Commonly encountered nerve injury etiologies in this population currently include compression, direct trauma, nutritional deficits, traumatic limb amputation, toxic chemical exposures, or blast-related injuries. Expeditious identification and comprehensive, interdisciplinary treatment of combat-associated neuropathies, as well as prevention of these injuries whenever possible is critical to reduce chronic morbidity and disability for service members and to maintain a well-prepared military. However, diagnosis of a combat-associated nerve injury may be particularly challenging due to comorbid battlefield injuries or delayed presentation of neuropathy from military toxic exposures. Advances in imaging for nerve injury, including MRI and ultrasound, provide useful tools to compliment EMG in establishing a diagnosis of combat-associated nerve injury, particularly in the setting of anatomic disruption or edema. Surgical techniques can improve pain control or restoration of function. In all cases, comprehensive interdisciplinary rehabilitation provides the best framework for optimization of recovery. Further work is needed to prevent combat-associated nerve injuries and promote nerve recovery following injury.

CASE REPORT: SEROTONIN SYNDROME IN AN INJURED SERVICEMAN DURING TREATMENT OF BLAST INJURY

Background. Serotonin syndrome is a life-threatening condition that may be caused by an unanticipated interaction of serotonergic drugs. Medications of this category are routinely prescribed during treatment of blast injury. Their effect on serotonin receptors should be taken into account to prevent the development of serotonin syndrome. Case description. A patient was transported from another hospital directly to the ICU to continue treatment of consequences of multiple blast injuries of lower limbs and abdomen, complicated by wound infection and clinical depression. Treatment with linezolid and duloxetine combined with repeated surgical interventions with opioid-based anesthesia has resulted in development of the serotonin syndrome, manifesting as tremor and frequent clonic seizures. Complete revision of the prescribed pharmacological therapy as well the approach to sedation and anesthesia has led to a complete resolution of clinical symptoms of this complication. Conclusion. In this case, improvement was achieved through discontinuation of fluoxetine and linezolid. All unfavorable drug interactions must be taken into account in management of complex blast injury. Limiting opioid use through regional anesthesia and prescription of sedative agents that do not promote serotonin accumulation may prevent the development of serotonin syndrome in such patients.

Parametric study to evaluate the influence of aspect ratio of cylindrical charges on blast pressures

The influence of the aspect ratio of a cylindrical charge on the spatial distribution of the effective pressure caused by an explosive blast on the front face of a concrete unit is investigated here. Distinct patterns of the spatial distribution of effective pressure can be discerned in the graphical comparison pertaining to the different aspect ratios. This can be attributed to the complex blast wave patterns generated by exploding cylindrical charges. The effective pressures decrease with an increase in the aspect ratio of the cylindrical charge. A 54% reduction in the effective pressure is observed when the aspect ratio is varied from 1 to 2. The study is expected to contribute to the ongoing research on the design and construction of blast-resistant structures, as cylindrical shaped charges are common in civil and military applications.

Operation "NeuroTeam": rendering the absolute best care for the most deserving patients under the most difficult conditions

The tenets of neurosurgery worldwide, whether in the civilian or military sector, espouse vigilance, the ability to adapt, extreme ownership, and, of course, an innate drive for developing a unique set of technical skills. At a time in history when the complexity of battlefield neurotrauma climaxed coupled with a chronic shortage of military neurosurgeons, modernized solutions were mandated in order to deliver world-class neurological care to our servicemen and servicewomen. Complex blast injuries, as caused by an increased incidence of improvised explosive devices, yielded widespread systemic inflammatory responses with multiorgan damage. In response to these challenges, the "NeuroTeam," originally a unit of two neurosurgeons as deployed during Operation Desert Storm, was redesigned to instead pair a neurosurgeon with a neurointensivist and launched itself during two specialized missions in Operations Iraqi Freedom and Enduring Freedom. Representing a hybridized version of present-day neurocritical care teams, the purpose of this unit was to optimize neurosurgical care by focusing on interdisciplinary collaboration in an Echelon III combat support hospital. The NeuroTeam provided unique workflow capabilities never seen collectively on the battlefield: downrange neurosurgical capability by a board-certified neurological surgeon within 60 minutes from the point of injury paired with a neurocritical care-trained intensivist. This also set the stage for intraoperative telemedicine infrastructure for neurosurgery and optimized the ability to evaluate, triage, and stabilize patients prior to medical evacuation. This novel military partnership ultimately allowed the neurosurgeon to focus on the tenets of the craft and thereby the dynamic needs of the patient first and foremost. Since the success of these missions, the NeuroTeam has evolved into a detachable unit, the "Head and Neck Team," comprising neurosurgeons, otolaryngologists, and ophthalmologists, supported by a postinjury hospital unit, which includes an embedded neurocritical care physician. The creation and evolution of the NeuroTeam, necessitated by a shortage of military neurosurgeons and the dangerous shift in military wartime tactics, best exemplifies multidisciplinary collaboration and military medicine agility. As neurocritical care continues to evolve into a highly complex, distinct specialty, the lessons learned by the NeuroTeam ultimately serve as a reminder for civilian and military physicians alike. Despite the conditions and despite one's professional ego, patients with highly complex morbid neurological disease deserve expert, multidisciplinary management for survival.

A Data-Based Compact High-Order Volterra Model for Complex Blast Furnace System

In this article, a data-based compact Volterra model is constructed to carry out the silicon prediction task. The main motivations are to, on the one hand, make better use of the strong memory ability of the Volterra series, which is suitable for reflecting the large inertia of the blast furnace process, on the other hand, overcome the difficulty that high complexity of the original Volterra models may result in serious overfitting. Six kinds of models, including single-input and two-input linear, second-order and third-order compact Volterra models, are successively designed and verified through a real blast furnace case. The reasonable agreement between the predicted values and the observed values indicates the compact Volterra model, especially the single-input third-order Volterra model, are powerful and competitive for describing the complex blast furnace system. The experimental results can serve as a guide for the blast furnace operators to judge the in-furnace thermal state change in time and further provide an indication on how to control the blast furnace in advance.

Zone 1 REBOA in a combat DCBI swine model does not worsen brain injury

BackgroundZone 1 resuscitative endovascular balloon occlusion of the aorta has been recommended for refractory shock after a dismounted complex blast injury for the austere combat scenario. While resuscitative endovascular balloon occlusion of the aorta should enhance coronary perfusion, there is a potential risk of secondary brain injury due to loss of cerebral autoregulation. We developed a combat casualty relevant dismounted complex blast injury swine model to evaluate the effects of resuscitative endovascular balloon occlusion of the aorta zone I on intracranial pressure and cerebral edema. We hypothesized that zone 1 aortic occlusion with resuscitative endovascular balloon occlusion of the aorta would increase mean arterial pressure transmitted in excessive intracranial pressure, thereby worsening brain injury. Methods50 kg male Yorkshire swine were subjected to a combination dismounted complex blast injury model consisting of blast traumatic brain injury (50 psi, ARA Mobile Shock Laboratory), tissue injury (bilateral femur fractures), and hemorrhagic shock (controlled bleeding to a base deficit goal of 10 mEq/L). During the shock phase, pigs were randomized to no aortic occlusion (n = 8) or to 30 minutes of zone 1 resuscitative endovascular balloon occlusion of the aorta (zone 1 aortic occlusion group, n = 6). After shock, pigs in both groups received a modified Tactical Combat Casualty Care–based resuscitation and were monitored for an additional 240 minutes until euthanasia/death for a total of 6 hours. Intracranial pressure was monitored throughout, and brains were harvested for water content. Linear mixed models for repeated measures were used to compare mean arterial pressure and intracranial pressure between zone 1 aortic occlusion and no aortic occlusion groups. ResultsAfter dismounted complex blast injury, the zone 1 group had a significantly higher mean arterial pressure during hemorrhagic shock compared to the control group (41.2 mm Hg vs 16.7 mm Hg, P = .002). During balloon occlusion, intracranial pressure was not significantly elevated in the zone 1 aortic occlusion group vs control, but intracranial pressure was significantly lower in the zone 1 group at the end of the observation period. In addition, the zone 1 aortic occlusion group did not have increased brain water content (zone 1 aortic occlusion: 3.95 ± 0.1g vs no aortic occlusion: 3.95 ± 0.3 g, P = .87). Troponin levels significantly increased in the no aortic occlusion group but did not in the zone 1 aortic occlusion group. ConclusionZone 1 aortic occlusion using resuscitative endovascular balloon occlusion of the aorta in a large animal dismounted complex blast injury model improved proximal mean arterial pressure while not significantly increasing intracranial pressure during balloon inflation. Observation up to 240 minutes postresuscitation did not show clinical signs of worsening brain injury or cardiac injury. These data suggest that in a dismounted complex blast injury swine model, resuscitative endovascular balloon occlusion of the aorta in zone 1 may provide neuro- and cardioprotection in the setting of blast traumatic brain injury. However, longer monitoring periods may be needed to confirm that the neuroprotection is lasting.

A combat casualty relevant dismounted complex blast injury model in swine.

Improvised explosive devices have resulted in a unique polytrauma injury pattern termed dismounted complex blast injury (DCBI), which is frequent in the modern military theater. Dismounted complex blast injury is characterized by extremity amputations, junctional vascular injury, and blast traumatic brain injury (bTBI). We developed a combat casualty relevant DCBI swine model, which combines hemorrhagic shock (HS) and tissue injury (TI) with a bTBI, to study interventions in this unique and devastating military injury pattern. A 50-kg male Yorkshire swine were randomized to the DCBI or SHAM group (instrumentation only). Those in the DCBI group were subjected to HS, TI, and bTBI. The blast injury was applied using a 55-psi shock tube wave. Tissue injury was created with bilateral open femur fractures. Hemorrhagic shock was induced by bleeding from femoral arteries to target pressure. A resuscitation protocol modified from the Tactical Combat Casualty Care guidelines simulated battlefield resuscitation for 240 minutes. Eight swine underwent the DCBI model and five were allocated to the SHAM group. In the DCBI model the mean base excess achieved at the end of the HS shock was -8.57 ± 5.13 mmol·L -1 . A significant coagulopathy was detected in the DCBI model as measured by prothrombin time (15.8 seconds DCBI vs. 12.86 seconds SHAM; p = 0.02) and thromboelastography maximum amplitude (68.5 mm DCBI vs. 78.3 mm in SHAM; p = 0.0003). For the DCBI models, intracranial pressure (ICP) increased by a mean of 13 mm Hg, reaching a final ICP of 24 ± 7.7 mm Hg. We created a reproducible large animal model to study the combined effects of severe HS, TI, and bTBI on coagulation and ICP in the setting of DCBI, with significant translational applications for the care of military warfighters. Within the 4-hour observational period, the swine developed a consistent coagulopathy with a concurrent brain injury evidenced by increasing ICP.

Ranger O Low Titer (ROLO): Whole Blood Transfusion for Forward Deployed Units.

First-time use of Ranger O Low Titer (ROLO) blood and implementation of a forward-walking blood bank using predetermined donors proved essential in the survival of a 33-year-old active duty soldier following a complex blast injury during combat operations. The patient sustained significant bone, soft tissue, and vascular damage and continued to deteriorate despite resuscitation with cold-stored whole blood (WB). Only after utilizing the ROLO battle drill and transfusing with fresh WB was the patient able to be stabilized and evacuated. In this case report, we discuss how ROLO walking blood bank takes the next step in aiding resuscitation, providing smaller, forward-deployed units with blood resupply without the administrative burden of storage, particularly in resource-scarce environments. We provide an overview of WB and contrast its use to that of component therapy. In conjunction with the Golden Hour, ROLO can be incorporated as the standard damage control resuscitation to reduce the risks of noncompressible hemorrhage. By taking precautionary steps in the pre-deployment setting, ROLO offers an invaluable alternative to conventional resuscitation.

Analysis of the blast wave – structure interface phenomenon in case of explosive events

Several structures need their response to blast loads to be investigated to grant an acceptable survivability level. To this purpose, experimental campaigns are complex, but some numerical methods are commonly exploited. The explosion pressure-time history is typically estimated characterizing the detonation of an energetically equivalent explosion involving the detonation of a specific amount of TNT. The pressure-time history at a point, fixed in space, involved by the blast wave is described by the Friedlander equation. A specific approach to modelling the complex blast wave–target structure coupling is reported in the UFC 3-340-02. This method, although consolidated and valid for aerospace, civil and mechanical structure, is not adopted in predictive simulations, which involve naïve methods for characterizing that interface phenomenon. This work aims to give an insight on the blast wave–structure interaction event. A methodological approach combining the Friedlander equation and the theory reported in the UFC 3-340-02 is presented, which confidently characterizes the effects of explosive loads on common structures. This fully analytical method may be implemented into numerical codes to perform simple, but effective, preliminary characterizations of the structural response to explosive loads. Finally, a possible application of the proposed method to thin-walled structures is shown.

On models of blast overpressure effects to the thorax

Shock waves from explosions can cause lethal injuries to humans. Current state-of the-art models for pressure induced lung injuries were typically empirically derived and are only valid for detonations in free-field conditions. In built-up environments, though, pressure–time histories differ significantly from this idealization and not all explosions exhibit detonation characteristics. Hence, those approaches cannot be deployed. However, the actual correlation between dynamic shock wave characteristics and gradual degree of injury have yet to be fully described. In an attempt to characterize the physical response of the human body to complex shock-wave effects, viscoelastic models were developed in the past (Axelsson and Yelverton, in J Trauma Acute Care Surg 40, 31S–37S, 1996; Stuhmiller et al., in J Biomech. https://doi.org/10.1016/0021-9290(95)00039-9, 1996). We discuss those existing modeling approaches especially in view of their viscoelastic behavior and point out drawbacks regarding their response to standard stimuli. Further, we suggest to fully acknowledge the experimentally anticipated viscoelastic behavior of the effective thorax models by using a newly formulated standard model for viscoelastic solids instead of damped harmonic oscillators. Concerning injury assessment, we discuss the individual injury criteria proposed along with existing models pointing out desirable improvements with respect to complex blast situations, e.g. the necessity to account for repeated exposure (criteria with time-memory), and further adaption with respect to nonlinear gas dynamics inside the lung. Finally, we present an improved modeling approach for complex blast overpressure effects to the thorax with few parameters that is more suitable for the characteristics of complex blast wave propagation than other current models.

Designed Antimicrobial Peptides Against Trauma-Related Cutaneous Invasive Fungal Wound Infections.

Cutaneous invasive fungal wound infections after life-threatening dismounted complex blast injury (DCBI) and natural disasters complicate clinical care. These wounds often require aggressive repeated surgical debridement, can result in amputations and hemipelvectomies and have a 38% mortality rate. Given the substantial morbidity associated with cutaneous fungal wound infections, patients at risk need immediate empiric treatment mandating the use of rapidly acting broad-spectrum antimicrobials, acting on both fungi and bacteria, that are also effective against biofilm and can be administered topically. Designed antimicrobial peptides (dAMPs) are engineered analogues of innate antimicrobial peptides which provide the first line of defense against invading pathogens. The antifungal and antibacterial effect and mammalian cytotoxicity of seven innovative dAMPs, created by iterative structural analog revisions and physicochemical and functional testing were investigated. The dAMPs possess broad-spectrum antifungal activity, in addition to being effective against Gram-negative and Gram-positive bacteria, which is crucial as many wounds are polymicrobial and require immediate empiric treatment. Three of the most potent dAMPs—RP504, RP556 and RP557—possess limited mammalian cytotoxicity following 8 h incubation. If these encouraging broad-spectrum antimicrobial and rapid acting results are translated clinically, these novel dAMPs may become a first line empiric topical treatment for traumatic wound injuries.

Military experience in the management of pelvic fractures from OIF/OEF

IntroductionPelvic fractures are a common occurrence in combat trauma. However, the fracture pattern and management within the most recent conflicts, i.e. Operation Enduring Freedom (OEF) and Operation Iraqi Freedom (OIF),...

Low-rank based Multi-Input Multi-Output Takagi-Sugeno fuzzy modeling for prediction of molten iron quality in blast furnace

For complex blast furnace smelting systems with large time delay, accurate prediction of molten iron quality indicators plays an important guiding role in blast furnace control. Recently, some data-driven Multi-Input Multi-Output (MIMO) modeling methods have been proposed to model multiple molten iron quality indicators including molten iron temperature (MIT), silicon content ([Si]), phosphorus content ([P]) and sulfur content ([S]). However, those data-driven MIMO models do not consider the inter-indicator correlation, which leads to the suboptimal model for the estimation of multiple molten iron quality indicators. This paper proposed a novel MIMO Takagi-Sugeno (T-S) fuzzy model with taking full account of the inter-indicator correlation. In the novel method, the inter-indicator correlation was explicitly modeled by a low-rank learning in a latent space that overcame the great challenge of jointly determining the fuzzy rules of MIMO T-S model and the inter-indicator correlation. For the corresponding optimization problem, an effective alternating optimization algorithm is presented. The validity of the proposed method is verified by simulation and comparison with some related methods on real blast furnace data.

A New Understanding of the Mechanism of Injury to the Pelvis and Lower Limbs in Blast.

Dismounted complex blast injury (DCBI) has been one of the most severe forms of trauma sustained in recent conflicts. This injury has been partially attributed to limb flail; however, the full causative mechanism has not yet been fully determined. Soil ejecta has been hypothesized as a significant contributor to the injury but remains untested. In this study, a small-animal model of gas-gun mediated high velocity sand blast was used to investigate this mechanism. The results demonstrated a correlation between increasing sand blast velocity and injury patterns of worsening severity across the trauma range. This study is the first to replicate high velocity sand blast and the first model to reproduce the pattern of injury seen in DCBI. These findings are consistent with clinical and battlefield data. They represent a significant change in the understanding of blast injury, producing a new mechanistic theory of traumatic amputation. This mechanism of traumatic amputation is shown to be high velocity sand blast causing the initial tissue disruption, with the following blast wind and resultant limb flail completing the amputation. These findings implicate high velocity sand blast, in addition to limb flail, as a critical mechanism of injury in the dismounted blast casualty.

Performance-based design of stainless steel profiled barrier blast walls

ABSTRACT The current blast wall design guidelines do not capture the random nature of underlying parameters. The main issues are the appropriate treatment of various uncertainties in the explosion loadings and the complex blast wall behaviour considering dynamic and nonlinearity effects. To capture these effects a new methodology needs to be developed based on probabilistic reliability assessment. To address this, the present study presents a framework for performance-based assessment of stainless-steel profiled barrier blast walls. Initially, a blast wall including consideration of the upper and lower connections is developed using an enhanced APDL finite element modelling programming package. For the performance-based design, blast wall structures are studied at serviceability, damage control and collapse prevention levels. The design criteria and the maximum allowable response values are initially investigated and discussed and subsequently optimal response target values are proposed for a performance-based assessment approach under various explosion loadings (i.e. hazards).

Numerical Review of Jones–Wilkins–Lee Parameters for Trinitrotoluene Explosive in Free-Air Blast

AbstractThe analysis of complex blast scenarios typically requires advanced computational methods such as multi-material Eulerian and coupled Eulerian–Lagrangian (CEL) analysis where Jones–Wilkins–Lee (JWL) equation of state is used to model the explosive material. While multiple sets of empirical JWL parameters for trinitrotoluene (TNT) explosives have been published over the past few decades, there is also a lack of guidelines and comparative studies on their applications for the blast analysis. A standardized description of the explosive material behavior allows for a better interpretation of results from research studies involving different blast scenarios and JWL parameters. In this paper, the authors utilize numerical finite element (FE) simulations to investigate the influence of different TNT JWL parameter sets on the blast wave characteristics of a free-air blast across different scaled distances. Utilizing multi-material Eulerian analysis, a series of spherical free-air blasts involving a 100-kg TNT charge modeled with different TNT JWL parameters are conducted. The blast wave characteristics including the incident overpressure, impulse, and time of arrival (TOA) are benchmarked against the empirical-based Kingery–Bulmash air blast formulations through the conventional weapon effect calculator conwep. It was found that the incident overpressure and impulse are highly sensitive to the JWL parameters, with differences as high as 40% at smaller scaled distances, while the influence on TOA is much less significant. This paper hopes to provide a guide for future users on the appropriate JWL parameter sets to model the air blast events involving TNT explosives.

In Situ Crosslinking Bionanocomposite Hydrogels with Potential for Wound Healing Applications.

In situ forming hydrogels are a class of biomaterials that can fulfil a variety of important biomedically relevant functions and hold promise for the emerging field of patient-specific treatments (e.g., cell therapy, drug delivery). Here we report the results of our investigations on the generation of in situ forming hydrogels with potential for wound healing applications (e.g., complex blast injuries). The combination of polysaccharides that were oxidized to display aldehydes, amine displaying chitosan and nanostructured ZnO yields in situ forming bionanocomposite hydrogels. The physicochemical properties of the components, their cytotoxicity towards HaCat cells and the in vitro release of zinc ions on synthetic skin were studied. The in situ gel formation process was complete within minutes, the components were non-toxic towards HaCat cells at functional levels, Zn2+ was released from the gels, and such materials may facilitate wound healing.

Postdeployment Fertility Challenges and Treatment in the Modern Era.

Current war-fighting environments have shifted dramatically over the past decade, and with this change, new types of injuries are afflicting American soldiers. Operative Enduring Freedom and Operation Iraqi Freedom have noted an increased use of sophisticated improvised explosive devices by adversaries. Injuries not frequently seen in previous conflict are dismounted complex blast injuries, which involve multiple proximal amputations, pelvic fractures, and extensive perineal wounds. Thus, an unforeseen consequence of the decreased mortality rate after these complex blast injuries is a new wave of U.S. service members facing the challenges of recovering from the catastrophic amputations and genitourinary injuries. New applications of sperm retrieval methods may be used in these specific populations, as they recover and wish to purse family-building goals. Spinal cord injuries, traumatic brain injuries, and considerations unique to the female soldier are explored in this review of urologic care in wounded veterans.

Urinary Tract Infections after Combat-Related Genitourinary Trauma.

Background: We examined clinical outcomes among combat casualties with genitourinary injuries after blast trauma. Methods: Characteristics, clinical care, urologic complications, and infections for subjects enrolled in the Trauma Infectious Disease Outcomes Study (TIDOS) were collected from Department of Defense (DOD) and Department of Veterans Affairs (VA) sources. Logistic regression identified predictors for urinary tract infections (UTIs) after genitourinary trauma. Results: Among 530 TIDOS enrollees who entered VA care, 89 (17%) sustained genitourinary trauma. The majority of subjects (93%) were injured via a blast and 27% had a dismounted complex blast injury (DCBI). Sexual dysfunction was reported with 36% of subjects, whereas 14% had urinary retention/incontinence and 8% had urethral stricture. Urologic complications were comparable between patients with and without DCBIs. Nineteen (21%) subjects had one or more UTI with a total of 40 unique UTI events (25% during initial hospitalization and 75% during subsequent DOD or VA care). The UTI incidence rate was 0.89 per patient-year during initial hospitalization, 0.05 per patient-year during DOD follow-up, and 0.07 per patient-year during VA healthcare. Subjects with UTIs had a higher proportion of bladder injury (53% vs. 13%; p < 0.001), posterior urethral injury (26% vs. 1%; p = 0.001), pelvic fracture (47% vs. 4%; p < 0.001), soft-tissue infection of the pelvis/hip (37% vs. 4%; p = 0.001), urinary catheterization (47% vs. 11%; p < 0.001), urinary retention or incontinence (42% vs. 6%; p < 0.001), and stricture (26% vs. 3%; p = 0.004) compared with patients with genitourinary trauma and no UTI. Independent UTI risk factors were occurrence of a soft-tissue infection at the pelvis/hip, trauma to the urinary tract, and transtibial amputation. Conclusions: Among combat casualties with genitourinary trauma, UTIs are a common complication, particularly with severe blast injury and urologic sequelae. Episodes of UTIs typically occur early after the initial injury while in DOD care, however, recurrent infections may continue into long-term VA care.

Hydration, Shrinkages and Mechanical Properties of Ultra High Performance Concrete Containing Blast Furnace Slag and Algerian Dune Sand

The new requirements for strength and durability have led to the development of Ultra High Performance concrete (UHPC) with outstanding mechanical properties and durability. However, the application of this type of concrete is exceptional, because of the high dosage of cement and the incorporation of expensive materials, such as silica fume (SF) whose dosage can reach 30% by weight of cement. This type of concrete is formulated on two bases: A fine granular skeleton (max diameter 630μm) and high cementitious materials content. The search for local materials to exploit them in the formulation of UHPC is the current trend. It is therefore necessary to control their effect on the behavior and evolution of cement hydration.The objective of this study is to highlight the influence of blast furnace (BFS) on hydration kinetics, linear endogenous shrinkage and chemical shrinkage at very early age (before 72h), drying shrinkage after hardening, as well as, the evolution of mechanical compressive strengths as a function of time. In addition, the exploitation of dune sand in the granular skeleton is an alternative to reduce the crushing energy and avoid microcracks possibly induced.The analysis of the results showed the interest of the use of the dune sand and the partial substitution of the cement by the BFS on the properties of the UHPCs in the fresh state and in the hardened state.In addition to the high performance achieved by UHPCs, their use, in Algeria, will meet both economic and ecological requirements given the abundance of very fine dune sand (southern Algeria) and complex blast furnace BFS of EL-Hadjar (Eastern Algeria).