Let ℛ be an o-minimal expansion of a real closed field R. We continue here the investigation we began in [11] of differentiability with respect to the algebraically closed field [Formula: see text]. We develop the basic theory of such K-differentiability for definable functions of several variables, proving theorems on removable singularities as well as analogues of the Weierstrass preparation and division theorems for definable functions. We consider also definably meromorphic functions and prove that every definable function which is meromorphic on Knis necessarily a rational function. We finally discuss definable analogues of complex analytic manifolds, with possible connections to the model theoretic work on compact complex manifolds, and present two examples of "nonstandard manifolds" in our setting.