Complete Penoscrotal Transposition Research Articles

Penoscrotal transposition: Long-term outcome in 29 patients.

Penoscrotal transposition (PST) is a rare anomaly of the external genitalia characterized by malposition of the penis in relation to the scrotum. This transposition may be partial or complete and may be associated with hypospadias, chordee, and other anomalies. We have reviewed our experience with the surgical repair of PST utilizing a modified Glenn-Anderson technique. Twenty-nine patients with a median age of 5.6 years (8 months -15 years) underwent surgical repair of PST at our institution between 2004-2022. Of those, 20 (69%) had complete PST, while 9 (31%) had partial PST. All children were divided into three groups. In the first group of 8 (28%) children, repair of PST was an integral part of one-stage male genitoplasty; in the second group of 18 (62%) children, repair of PST was an isolated last stage of the staged hypospadias repair and the remaining 3 (10%) children underwent PST repair without the presence of hypospadias. All patients underwent modification of the Glenn-Anderson technique involving utilization of bilateral rotational advancement scrotal flap, complete de-tethering of the testis from the internal part of the scrotum when indicated, and relocation of the scrotal compartment in a normal dependent position. The follow-up ranged from 6 months to 18 years. In the first group, five children (62%) underwent Onlay Prepucial Island Pedicle Flap (OIF) hypospadias repair, and three (38%) underwent Long Tubularized Incised Plate Repair (TIP). In the second group, 8 (44%) underwent OIF hypospadias repair, 2 (12%) had Long TIP repair, and the remaining 8 (44%) underwent staged hypospadias repair. Post-operative Clavien Dindo grade III presented among three patients in group I and only one patient in group II. In the third group, no postoperative complications were observed. Our data show that penoscrotal transposition correction utilizing the Glenn-Anderson technique is a reliable and durable surgery in the pediatric population. These children require careful monitoring till adolescence to ensure that no re-operation is needed.

Surgical treatment of perineal hypospadias with complete penoscrotal transposition in DSD patients: Our experience with a “three-staged” reconstructive procedure

Surgical treatment of perineal hypospadias with complete penoscrotal transposition in DSD patients: Our experience with a “three-staged” reconstructive procedure

Bilateral Fetal Hydronephrosis presenting with Complete Penoscrotal Transposition at Birth: What to tell the Prospective Parents?

Bilateral Fetal Hydronephrosis presenting with Complete Penoscrotal Transposition at Birth: What to tell the Prospective Parents?

Surgical management and long‐term outcome of complete penoscrotal transposition in a dog

AbstractA 1.66 kg, approximately 4‐week‐old, intact male canine mixed breed was evaluated for 'urinating backward'. Genitourinary evaluation revealed that the preputial opening was not patent, and his penis traversed in a caudal direction, exiting in the perineum caudal to the scrotum. Testicles were not palpated at this time. Over an 8‐week period as the dog continued to undergo musculoskeletal maturation, the scrotum would become intermittently infected, and the dermal exit site of the penis constricted the penis resulting in marked paraphimosis. En bloc preputial resection, phallectomy, scrotal ablation, castration and perineal urethrostomy (PU) were performed to correct this abnormality. Histopathology confirmed only a left testicle within the scrotum. Abdominal imaging and anti‐Mullerian hormone assay confirmed right testicular cryptorchidism. Two months after the initial surgery, successful removal of the retained right testicle was performed, and the dog was reported to be urinating through the PU stoma normally. This is the first reported case of penoscrotal transposition in a dog.

Complete Penoscrotal Transposition: A Case Report

Penoscrotal transposition is an extremely rare congenital anomaly of the external male genitalia, characterized by malposition of the penis in relation to the scrotum. There are two types of penoscrotal transposition variants, complete and incomplete. In this case report, an 11-year-old boy with complete penoscrotal transposition is described with radiological and physical examination findings.

A rare case of complete penoscrotal transposition with hypospadias in a newborn.

A rare case of complete penoscrotal transposition with hypospadias in a newborn.

Prepubertal diagnosis of Klinefelter syndrome due to penoscrotal malformations: Case report and review of literature.

We report a case of 4 months old infant diagnosed as Klinefelter syndrome associated with perineal hypospadias, severe ventral chordee and complete penoscrotal transposition. A review of previous reported cases was carried out. Penoscrotal malformations at birth are very rare in Klinefelter syndrome. Awareness of the current standard indications of Karyotyping can help early detection of these cases.

Complete penoscrotal transposition

Penoscrotal transposition, where malposition of penis occur in relation to scrotum. It is frequently associated with malformation of genitourinary, cardiovascular or skeletal system. As it is extremely rare no standard treatment protocol exist. We here represent a newborn baby with complete penoscrotal transposition, died 5 hours after birth due to complication of perinatal asphyxia.

25. Complete penoscrotal transposition and bilateral renal cystic dysplasia

Introduction Complete penoscrotal transposition is a rare male genital malformation where the scrotum is located entirely cephalad to the penis. This malformation is most commonly associated with congenital abnormalities involving the genitourinary system but anomalies of the gastrointestinal, cardiovascular and the central nervous systems have also been described. Case report We present a case of a twenty-four week old foetus with oligohydramnios, bilateral hydronephrosis, enlarged kidneys, thickened nuchal fold and abnormal limbs on antenatal ultrasound. The pregnancy proceeded to termination based on these features being incompatible with life. At autopsy, the foetus was found to have a complete penoscrotal transposition with hypospadias and urethral meatus stenosis. Both kidneys were markedly enlarged and cystic on macroscopic appearance. Microscopic examination confirmed bilateral renal cystic dysplasia with hydronephrosis. No other congenital abnormalities were identified. Discussion There are only a small number of cases of complete penoscrotal transposition reported in the literature. An association between genital malformations, including penoscrotal transposition, and distal deletions of the long arm of chromosome 13 have been reported, with this region encoding the EFNB2 gene. A brief review of the literature and genetic associations of penoscrotal transposition ensues.

Spectrum of penoscrotal positional anomalies in children

Background: The normal relationship between the scrotum and penis during fetal development is controlled by several genetic and hormonal factors, and impairment of this positional relation results in a wide spectrum of positional congenital anomalies. Objective: This a cohort study analysing 63 cases of penoscrotal anomalies (PSAs) according to severity and other associated malformations to provide a simple classification for recognising, describing and categorizing cases that may require surgical correction. Design and setting: Between 2005 and 2013, 63 diverse cases of penoscrotal positional anomaly were detected and analysed based on their hormonal profile and other associated anomaly. Results: A wide variety of PSAs were included in the study, 11 cases were of major PST with complete penoscrotal transposition in three, incomplete in eight, and minor degree in 45 cases, which are symmetrical (bilateral) in 29, sixteen are asymmetrical, 4 had midline scrotlisation, and 3 had wide penoscrotal distance. Associated genitourinary anomalies were detected in 29 babies. Sex hormonal assays showed no significant differences between the PSA patients and controls (P < .05), and no gross chromosomal anomalies were detected in any cases. Conclusion: Penoscrotal positional anomalies include the previously described penoscrotal transposition, and the variants of a central penile scrotalisation, and wide penoscrotal distance. A simple classification for these anomalies adopted herein.

Transposición pene-escrotal completa: diagnóstico prenatal

We report a case of prenatal diagnosis of complete penoscrotal transposition in a fetus at 20 weeks of gestation. Systematic exploration of all the organs, including the genitals, allowed the diagnosis of these rare malformations.

(Article Withdrawn) A case of complete penoscrotal transposition

The Journal is the primary organ of Continuing Paediatric Medical Education in Sri Lanka. The journal also has a website. Free full text access is available for all readers.The Sri Lanka Journal of Child Health is now indexed in SciVerse Scopus (Source Record ID 19900193609), Index Medicus for South-East Asia Region (IMSEAR), CABI (Centre for Agriculture and Bioscience International Global Health Database), DOAJ and is available in Google, as well as Google Scholar.The policies of the journal are modelled on the Committee on Publication Ethics (COPE) Guidelines on Principles of Transparency and Best Practice in Scholarly Publishing. Sri Lanka Journal of Child Health is recognised by the International Committee of Medical Journal Editors (ICMJE) as a publication following the ICMJE Recommendations.

Potter’s Syndrome associated with Pouch Colon Anomaly in Exomphalos

Potter’s Syndrome is a rare congenital malformation which is an atypical physical appearance of the foetus or neonate due to Oligohydramnios experienced in the womb with distinctive facial characteristics. Oligohydramnios is the cause of the various deformities observed in Potter’s Sequence. It is characterised by bilateral renal agenesis, pulmonary hypoplasia, and skeletal defects of the neonate as a direct result of lack of amniotic fluid. Congenital pouch colon (CPC) is an extremely rare variant of anorectal malformation (ARM), in which varying lengths of the colon is replaced by a dilated pouch accompanied by a fistula communicating with the genitourinary tract. Complete Penoscrotal Transposition (CPST) is a rare and unusual malformation in which the scrotum is located cephalic to the penis. It is associated with major and often life threatening malformations. The present case has multiple malformations which include, potter’s syndrome, congenital pouch colon in omphalocele and complete penoscrotal transposition. The aim of this study was to determine the incidence, prevalence of these multiple malformations according to anatomical localization. This complex anomaly is very rare and interesting. Survival is extremely rare. In view of prognosis early diagnosis allows for earlier and less traumatic therapeutic abortion.

Complete penoscrotal transposition: A three-stage procedure

Complete penoscrotal transposition (CPST) with an intact scrotum is a rare anomaly in which the scrotum is located cephalic to the penis. It is the most severe degree of malformation of a spectrum of abnormalities in scrotal development. There are few cases reported in the literature, and there are few descriptions of the technique for correction and results. We describe a new case of CPST and its sequential correction.

Successful surgical correction of an extreme form of ectopic penis

Reported here is the successful multi-staged repair of a rare case of complete penoscrotal transposition with ectopic penis. The need to evaluate for associated anomalies is discussed.

Complete penoscrotal transposition

Penoscrotal transposition is an uncommon congenital malformation of the external genitalia, in which the scrotum is malpositioned superior and anterior to the penis. This anomaly must be viewed as part of a spectrum of abnormalities in scrotal development, ranging from bifid scrotum to the very rare condition of complete penoscrotal transposition (CPST). In this extreme degree of malformation, the scrotum is located cephalic to the penis. Few cases of CPST have been reported and even fewer images shown in modern urologic literature.

Female pseudohermaphroditism associated with cloacal anomalies: Faulty differentiation in the caudal developmental field

A 1½-year-old girl with a urogenital sinus defect associated with an enlarged phalluslike clitoris is described. The child had an anteriorly located anus, a single kidney with grade III vesicoureteric reflux, a 3.5-cm-long common urethrovaginal channel, a large vesical calculus, and a hamartoma in the pubic region. After a preliminary colostomy, definitive surgery consisted of urethral reconstruction, vaginal reconstruction using a colonic graft, and posterior relocation of the anus. The discussion centers on a review of the previously reported cases of female pseudohermaphroditism associated with cloacal or urogenital sinus defects (FPHCD). The likely embryogenesis of this condition is discussed, and the similarity of the features with those seen in some patients with complete penoscrotal transposition (CPST) is highlighted. J Pediatr Surg 36:E9. Copyright © 2001 by W.B. Saunders Company.

Peno-Scrotal Transposition

Peno-scrotal transposition is an infrequent genital malposition due to a defect in the caudal migration of the inchoate scrotum during intrauterine life. It is frequently associated with urogenital and/or gastrointestinal malformations. Glenn and Anderson (1973) have classified the abnormality into the following categories, according to severity: Bifid scrotum Incomplete or partial peno-scrotal transposition Complete peno-scrotal transposition or pre-penile scrotum Ectopic scrotum We analyse corrective surgical techniques for this malposition and we present our experience.

Association familiale d'une transposition pénoscrotale et diphallia (pénis double) à une aplasie rotulienne

Background. - Diphallia and penoscrotal transposition are rare, generally sporadic, abnormalities. Case reports. - Case 1: A 2-1/2-month old boy was admitted in hospital because he suffered from complete penoscrotal transposition, with moderate hypospadias for which he was operated on. Examination at the age of 6 years showed hypoplastic and dislocated patellae. Case 2: A 2-month-old boy, brother of case 1, also suffered from incomplete penoscrotal transposition, associated with diphallia but without double bladder, that was operated on. Ultrasonography at the age of 17 months showed absence of patellae. The sister of these two patients was normal but her mother displayed ambiguous genitalia with phallic structure located beneath partially fused labial folds. Her patellae were also absent. Conclusion. - This is the first familial case of true diphallia associated to penoscrotal transposition. This abnormality is also associated to absence of patellae and seems to be dominantly inherited.

Prepenile Scrotum

The clinical history and pertinent illustrations of the surgical repair of 2 patients seen with complete penoscrotal transposition are presented. The results of the corrective surgery were highly satisfactory from both the genitourinary and psychological standpoints.