The current work is devoted to the solid-phase concentration of phenolic compounds from the aqueous extracts of medicinal plant raw materials using the various sorbents for their further identification. Plants of the Hypericaceae ( Hypericum perforatum L.) and Lamiaceae ( Thymus serpyllum L., Salvia officinalis L.) families were selected as samples in this effort. For each of the sorbents, the main sorption characteristics («breakthrough volumes» and dynamic sorbents capacities) in relation to the target compounds, as well as their desorption parameters (concentration factor and recoveries) were obtained. Strata X and Oasis HLB polymeric materials allowed extracting the target compounds from the water extracts of plants at five-, and in the case of hydrophilic-lipophilic sorbent at 32- and 20-fold concentration. Strata C18-Е showed complete desorption of flavonoids ( R ≥ 90%), but in relation to the phenolic acids, its use was impractical due to the low values of recovery analytes ( R ≤ 40%). The Oasis HLB sorbent had universal sorption properties, which provided high concentration coefficients at acceptable values of recoveries of phenolic acids ( R ≤ 96%) and flavonoids ( R ≤ 91%). The sorption of phytocomponents with the Supelclean ENVI-Carb sorbent gave quite high characteristics, but the process of desorption of these compounds was difficult and requires further study. The use of the various types of sorbents showed that minor components that were not detected under the usual conditions of their chromatographic determination could be concentrated by SPE for their further identification, which would provide an extension of the range of definable compounds in various medicinal plants. Key words: St. John's wort, thyme, sage, solid phase extraction, flavonoids, phenolic acids, medicinal raw materials DOI: http://dx.doi.org/10.15826/analitika.2020.24.2.002 Z. A. Temerdashev, Е. А. Vinitskaya, V. V. Milevskaya, N. V. Kiseleva Kuban State University, ul. Stavropolskaia, 149, Krasnodar, 350040, Russian Federation