In this study, the feasibility of constructing multi-energy complementary systems in rural areas of China is examined. First, the rural energy structure and energy utilization in the eastern, central, and western regions of China are analyzed, and the development and utilization modes of multi-energy complementary systems in different regions are evaluated based on the differences in the resource endowment in different regions. Second, the input-output status of the multi-energy complementary mode in different regions is analyzed. Then, based on the assumption of technical feasibility, the feasibility of the multi-energy complementary system is analyzed in terms of various dimensions, such as economic, energy conservation, environmental protection, and social benefit. Finally, an empirical study is conducted by comparing the proposed multi-energy complementary system with traditional energy supply system. The results show that the development of a multi-energy complementary system in each region is feasible from the perspective of multiple dimensions to reduce environmental pollution, create employment opportunities, and improve the economy. Moreover, the system can significantly reduce the peak-valley difference and improve energy efficiency.