The topological index is just one of several very useful tools that graph theory has made available to chemists. Topological indices are invariants of real numbers under graph isomorphisms. Several topological indices have been defined. Some of them are used to model chemical, pharmaceutical and other properties of molecules. The eccentric connectivity index (eci) is also a topological index. The eci of [Formula: see text], denoted by [Formula: see text], is defined as [Formula: see text], where [Formula: see text] represents the degree of a vertex [Formula: see text] and [Formula: see text] is its eccentricity. In this paper, exact formula for the eci of complementary prisms is derived.