This paper investigates the current situation of subscription mode, applies it to the joint management of pricing and inventory in supply chain management, builds the product pricing and inventory model under subscription mode, and verifies the model derivation and results based on the joint decision model of pricing and inventory, and simulates the decision-making process of the model by computer programming. By comparing the difference between the theoretical model of joint decision of pricing and inventory under uncertain supply and demand conditions and the model of joint decision of pricing and inventory under subscription mode, analyzing the influencing factors and exploring the optimization method of product pricing and inventory model algorithm under subscription mode. The results show that: (1) in supply chain management, it is necessary to solve the problem of supply and demand balance through effective joint decision of pricing and inventory, and effectively improve the competitiveness of logistics enterprises.(2) The introduction of subscription mode in the joint management of pricing and inventory can reduce the uncertainty of both sides, so as to better solve the problem of inventory replenishment strategy and pricing decision under the condition of supply and demand uncertainty than the traditional decision-making model, so as to achieve the coordination of supply chain under the uncertain environment.