The Advanced Practitioner Society for Hematology and Oncology (APSHO) launched its first oncology and hematology advanced practitioner (AP) compensation survey in 2022. This 74-question survey surveyed nurse practitioners, pharmacists, physician assistants, clinical nurse specialists, and advanced practice nurses in oncology, investigating all aspects of compensation structure, including salary, on-call payments, incentive structures where applicable, and consulting rates to work with industry partners. Data also include a concerning rate of AP burnout and intent to alter current work status by leaving the practice, leaving the specialty, reducing work hours, or leaving health care all together. Results from this survey may be beneficial in the recruitment, retention, and promotion of the AP in hematology and oncology.