Fixed time tracking control for nonstrict feedback high-order nonlinear systems with unknown time-varying external disturbance and unknown time-varying input delay has been studied in this research. Firstly, the obstacle caused by unknown time-varying input delay has been tackled by introducing a compensation signal. The unknown nonlinear functions are identified by neural networks and the algebraic loop problem for nonstrict feedback systems has been overcome by using the properties of neural networks. Further, a bound estimation mechanism is employed to estimate the identify error and unknown time-varying external disturbance without using the priori knowledge of the boundary. Regarding the obstacle caused by high-order terms and the singularity problem have been tackled by using adding a power integrator mechanism and the inequality transformation technique, respectively. The boundedness of all the signals in the closed-loop systems has been proved by using the Lyapunov stability theorem, and the convergence time is independent of the initial value of the system state. Finally, the simulation results show the effectiveness of the proposed method.