In this article, a study of interdisciplinary connections in the process of studying the discipline "Safetyof life and the basics of labor protection" by future specialists of the mechanical engineering profile is carriedout.The purpose of the article is the study of interdisciplinary connections in the process of studying thediscipline "Safety of life and the basics of occupational health and safety" by future specialists in the field ofmechanical engineering.The research was conducted independently in two academic groups with different levels of success,where students received grades on a stobal scale in different disciplines. The work compared the results ofstudents' success during the study of the following disciplines: "Physics", "Higher Mathematics", "Ecologyand the basics of biosafety and bioethics" and "Life safety and the basics of occupational health and safety".The comparison of variances of different samples was performed using Fisher's test. The strength ofintersubject relationships was determined by the correlation method. A graphical interpretation of the levels ofinter-subject connections between the discipline "Safety of life and the basics of occupational safety" and suchsubjects as "Higher mathematics", "Physics", "Ecology and the basics of biosafety and bioethics" was built fortwo academic groups with different success rates. With 95% reliability, the hypothesis about the existence ofhomogeneity of different samples and their belonging to one general population (future specialists of themechanical engineering profile) has been proven.The studies carried out in the work testify to the existence of strong interdisciplinary connections in theprocess of studying the regulatory discipline "Safety of life and the basics of labor protection" by futurespecialists of the mechanical engineering profile. The determination of interdisciplinary connections duringthe study of such a discipline as "Civil defense and labor protection in the industry" by future specialists of themechanical engineering profile requires further research.