The Indonesian archipelago is situated in a highly active geological zone, making it prone to frequent earthquakes. West Sumatra, located on the west coast of central Sumatra, comprises lowland coastal areas and volcanic plateaus formed by the Barisan Mountains, covering a land area of 42,297.30 km² (2.17% of Indonesia's territory). This research aims to determine which interpolation method—Inverse Distance Weighted (IDW) and Thin Plate Spline (TPS)—provides more accurate predictions of earthquake strength in West Sumatra. The dataset consists of 229 earthquake events, divided into 90% for training (206 points) and 10% for testing (23 points). The training data was further subdivided into 80% training data 2 (164 points) and 20% validation data (42 points). The interpolation processes using the IDW and TPS methods were repeated 100 times, with the training 2 and validation data randomly shuffled in each iteration. Visualization of the interpolation results indicated that the earthquake magnitudes ranged from 2.0 to 4.5. Although the Mean Absolute Percentage Error (MAPE) values for the TPS method on the test and validation datasets were 16.42 and 14.29, respectively—slightly lower than the MAPE values for the IDW method—the t-test results showed no statistically significant difference between the two methods. Statistically, there is no significant difference between IDW and TPS in terms of predictive accuracy. However, researchers prefer the IDW method due to its computational efficiency and simplicity. Therefore, IDW is considered the most suitable method for analyzing earthquake strength in the West Sumatra region