Comparison Of Bone Loss Research Articles

Comparison of bone loss around implants using radiographs

This article presents an original-research conducted at Pushpagiri College of Dental sciences, Thiruvalla, Kerala to compare and evaluate the vertical crestal bone changes around implants with different surface coatings and diame-ter using CBCT and RVG taken at the time of loading and one year after loading. Thirty-six samples were divided in 4 group; based on 3 parameters: implant surface coating, implant diameter, and single versus multiple implants sup-ported bridges. Length of all implants is kept standardised at 10 mm. Data were statistically analyzed by Students paired t-test and comparison between CBCT and RVG is done using interclass correlation test. The mean crestal bone loss has increased statistically significant from the time of loading and after one year of loading. The average crestal bone loss on single implants were less compared to multiple implants supported bridges at both timings. CBCT shows more accurate and reliable values than RVG both clinically and statistically. It was concluded that crestal bone loss was less among single implants with calcium phosphate surface coating and wider diameter than alumina blasted and narrow diameter implants. Single implant shows less bone loss than multiple implants. The CBCT shows a reliable method of detecting circumferential peri-implant bone defects than RVG.

Assessment of Alveolar Bone and Periodontal Status in Peritoneal Dialysis Patients.

Chronic kidney disease (CKD) affects 8–13% of the global population and has become one of the largest burdens on healthcare systems around the world. Peritoneal dialysis is one of the ultimate treatments for patients with severe CKD. Recently, increasing severe periodontal problems have been found in CKD patients. Periodontitis has been identified as a new variable risk factor for CKD. The aim of this study was to investigate the periodontal status and severity of alveolar bone loss in CKD patients with peritoneal dialysis (PD). One hundred and six patients undergoing PD (PD group) and 97 systemically healthy periodontitis patients (control group) were enrolled. The differences in the dimensions of the alveolar bone between two groups were compared, and the distribution of alveolar bone defects was analyzed by cone-beam computed tomography (CBCT). Gingival index (GI), plaque index (PLI), periodontal probing depth (PPD), and attachment loss (AL) were recorded. The levels of inflammatory factors in gingival crevicular fluid were assessed by ELISA. Compared to control group, there was a higher degree of alveolar bone loss in maxillary premolars, maxillary 2nd molar and mandibular 1st molar in patients with PD (p < 0.05). A comparison of bone loss in different sites revealed that the area with the highest degree of bone loss were on the mesial-buccal, mid-buccal, distal-buccal, and mesial-lingual site in PD patients. The expression levels of inflammatory factors were higher in PD group (p < 0.01). In conclusion, PD patients presented more severe periodontal and inflammatory status than systemically healthy periodontitis patients. The loss of the alveolar bone differed between the two groups. Different sites and teeth exhibited a diverse degree of bone loss. This study highlights that clinicians should pay close attention to periodontal status of peritoneal dialysis patients and provides a new thinking to improve healthcare for CKD.

Different bone sites-specific response to diabetes rat models: Bone density, histology and microarchitecture

Background and purposeDiabetes mellitus (DM) is the most common metabolic disorder that is characterized by hyperglycemia, it can be categorized by T1DM and T2DM. T1DM is also reported to cause bone loss. However, most reports regarding this aspect of T1DM have only investigated a single site; a comparison of bone loss from different areas of the body is still lacking.MethodsThirty-five 12-week-old Sprague Dawley® (SD) rats were separated to seven groups. Five rats were euthanized without any surgery at 0 weeks for histological examination and determination of baseline characteristics. In 15 of the rats, DM was induced via Streptozotocin (STZ)-injection, and they were separated to 3 groups (4 weeks, 8 weeks and 12 weeks after STZ-injection). The remaining 15 rats were used as the control group (4 weeks, 8 weeks and 12 weeks after saline-injection). We tested bone-mass loss at four skeletal sites, the tibia, the femur greater trochanter, the spine, and the mandibular bones using micro-computed tomography (CT) and histological tests.ResultsTibia was influenced the most obvious(BV/TV decreased by 27.3%, 52.5%, and 81.2% at 4 weeks, 8 weeks, and 12 weeks, respectively. p<0.05). In contrast, the other three sites were influenced to a lesser extent and bone loss became prominent at a later time point according to the histological and micro-CT tests(Femur: BV/TV did not decrease significantly at the first month or second month. However, and decreased by 49.4% at the third month, P<0.05. Mandible: the BV/TV only decreased by 6.5% at 1 month after STZ-injection. There was still a significant difference between the second and third months. The BV/TV decreased by 47.0% and 68.1% at 2 months and 3 months, respectively, (p<0.05) Spine: the BV/TV only decreased by 6.7%. However, significant change was observed in the spine at the second month and third month after STZ injection. The BV/TV decreased by 45.4% and 64.3%, respectively, p<0.05).ConclusionThe results indicate that T1DM can severely influence the bone structure of the 4 skeletal sites. Further, areas with dense trabecular bones were influenced less and at a later time point in comparison to the tibial region.Clinical relevanceOur research can serve as a guide to help increase the success rate of implant treatment, and help decrease the fracture risk in different bone types with greater accuracy.

Assessment of Alveolar Bone Status in Middle Aged Chinese (40-59 Years) with Chronic Periodontitis--Using CBCT.

ObjectiveThis study used con-beam computed tomography (CBCT) to investigate the prevalence and severity of alveolar bone loss in middle-aged (40–59 years) Chinese with chronic periodontitis.Materials and MethodsThe study group comprised 145 dentate individuals aged 40 to 59 years residing in China who suffered from chronic periodontitis. CBCT and the application of NNT software were used to examine the level and location of alveolar bone loss.ResultsThe study revealed that 40–59 year old patients with chronic periodontitis had severe bone loss. At 5,286 sites (34.7%), alveolar bone loss was mild; severe alveolar bone loss was found at 5,978 sites (39.2%). A comparison of bone loss in different jaws revealed that the area with the highest degree of bone loss was on the lingual side of the maxillary molar (56.3 ± 7.2%), and that the area with the lowest degree was primarily on the lingual side of the mandibular canine (27.5 ± 6.3%). There was a lower degree of alveolar bone loss in males than females. Differences were observed when comparing the incidence of bone loss between males and females (P < 0.05). Menopause in females and smoking in both genders may affect the level of bone loss. Male smokers experienced a greater degree of bone loss (41.67 ± 5.76%) than male non-smokers (32.95 ± 4.31%). A 42.23 ± 6.34% bone loss was found in menopausal females versus 31.35 ± 3.62% in non-menopausal females.ConclusionsThe study revealed that different sites and teeth exhibited a diverse degree of bone loss. In middle-aged patients with chronic periodontitis, the highest degrees of bone loss in the incisors, premolars, and molars were on the lingual side, mesial side and lingual side, respectively. Menopause in females and smoking may affect the level of bone loss.

Mesiodistal Bone Loss of Fresh Socket Placed Implants and Delay Placed Implants at the Anterior of the Maxilla

Introduction: Immediate implant placement in fresh extraction sockets provides the advantage of shorter treatment time along with minimizing the number of surgical interventions. Materials and methods: Subjects were studied in two groups: in group 1, subjects received a fresh socket placed implant at the anterior of the maxilla and in group 2, a delay placed implant was inserted at the same site. The mesial and distal marginal bone level was measured using parallel technique radiography in time 0, 12, 24 and 36 months after loading. Results: Seventy subjects were studied in two groups. Analysis of the data using a repeat measure test demonstrated the similar bone loss patterns between two groups. Time has a significant effect on bone loss in time 1, 2, 3. The amount of bone loss increased as time passed after loading time. Comparison of bone loss in both groups demonstrated that the amount of bone loss in the central site was more than the lateral site in three measurement times for the group 2 but in the group 1, a significant difference was not observed. Conclusion: Comparison of marginal bone loss in fresh socket placed implants and delay implants did not show a significant difference. Also a continuous bone resorption was observed over the time in the both groups. It may be needed to investigate other success criteria in fresh socket placed implants for making an appropriate treatment plane.

Comparison of bone loss during normal lactation to other osteopenic conditions in the rat.

Comparison of bone loss during normal lactation to other osteopenic conditions in the rat.

Comparison of bone loss during normal lactation to other osteopenic conditions in the rat

Comparison of bone loss during normal lactation to other osteopenic conditions in the rat

3. Comparison of bone loss in the proximal femur of females over two centuries

3. Comparison of bone loss in the proximal femur of females over two centuries

A comparison of bone loss from different skeletal sites during acute calcium deficiency in mice

Severe Ca deficiency was produced by the combined stresses of a Ca-deficient diet and lactation in female mice. Alveolar bone loss was assessed by changes in alveolar crest height and in quantity of supporting trabecular bone. Changes in the femur were measured by changes in mineral content and in the cross-sectional area of the midshaft region, and in vertebrae by changes in mineral content. A similar decrease in bone was observed in all sites during progression of Ca deficiency with a similar increase during recovery. Maximum bone loss amounted to more than 50 per cent. Alveolar bone loss was characterized by a reduction in trabecular bone without loss of alveolar crest height.