Comparative Analysis Of Clinical Outcomes Research Articles

Comparative Analysis of Clinical Outcomes and Procedural Costs between the Conventional Two-stage Technique and 4D Brachytherapy for Early Prostate Cancer

AimsTo assess long-term outcomes and resource use of 4D Brachytherapy, a one-stage real-time implant for the treatment of prostate cancer that uses stranded and loose iodine-125 seeds, and to compare with the conventional two-stage (2S) technique. Materials and methodsProspectively collected data of men who underwent 2S and 4D low dose rate brachytherapy in a single institution were analysed. Survival estimates were analysed using the Kaplan–Meier method and Log-rank test. Treatment failure rates were further compared by Cox proportional hazards (Coxph) regression or by a surrogate prostate-specific antigen value cut-off of 0.4 ng/ml 48 months post-implant. Treatment toxicity outcomes were also evaluated. Comparative costs were based on published English National Health Service data. ResultsWe compared outcomes of 690 men treated with 2S and 1031 men with 4D brachytherapy. Median follow-up times were 10.4 and 5.2 years (P < 0.001) for 2S and 4D cases, respectively. Day 0 post-implant dosimetry was improved in 4D brachytherapy patients. Five years post-implant ≥98% of cases were alive and ≥95% were free from disease relapse irrespective of technique. Coxph regression showed the risk of relapse after 4D brachytherapy was similar to the 2S technique (hazard ratio 0.67, 95% confidence interval 0.44–1.03, P = 0.065). Forty-eight months post-implant there was a significantly greater proportion of 4D brachytherapy cases with a prostate-specific antigen below 0.4 ng/ml relative to the 2S technique. Urinary and bowel symptom scores showed reduced toxicity after 4D implants and potency conservation was similar to the 2S technique. The reduction in time and resource use decreased the cost of 4D brachytherapy by 40% compared with the 2S technique. ConclusionTwo-stage and 4D brachytherapy are both highly effective for the control of localised prostate cancer. However, relative to the 2S technique, the 4D technique was associated with improved dosimetry, reduced treatment-related toxicity and reduced cost. Further follow-up will assess disease control superiority of 4D brachytherapy beyond 5 years post-implant.

Inter-Facility Transport on Extracorporeal Life Support: Clinical Outcomes and Comparative Analysis with In-house Patients.

BackgroundExtracorporeal life support (ECLS) is widely used in refractory heart or lung failure, and the demand for inter-facility transportation on ECLS is expanding. However, little is known about post-transportation outcomes, the clinical safety of such transportation, or the characteristics of the transported patients.MethodsThis was a retrospective review of a 3-year, single-institution experience with inter-facility ECLS transport, as well as a comparative analysis of clinical outcomes with those of in-house patients. We also analyzed the risk factors for hospital mortality in the entire ECLS population using univariate and multivariate analyses to investigate the effects of transport.ResultsAll 44 patients were safely transported without adverse events. The average travel distance was 178.7 km, with an average travel time of 74.0 minutes. Early survival of the transported group seemed to be better than that of the in-house group, but the difference was not statistically significant (70.5% vs. 56.6%, p=0.096). The incidence of complications was similar between the 2 groups, except for critical limb ischemia, which was significantly more common in the transported group than in the in-house group (25.0% vs. 8.1%, p=0.017). After adjusting for confounders, being part of the transported group was not a predictor of early death (adjusted odds ratio, 0.689; p=0.397).ConclusionTransportation of patients on ECLS is relatively safe, and the clinical outcomes of transported patients are comparable to those of in-house ECLS patients. Although matched studies are required, our study demonstrates that transporting patients on ECLS did not increase their risk of hospital mortality after adjustment for other factors.

Effect of Gastroparesis Etiology on Clinical Response to Gastric Peroral Endoscopic Pyloromyotomy (GPOEM)

Introduction: Gastroparesis is a heterogenous disorder with broad clinical spectrum. Etiology of gastroparesis was shown to influence clinical severity and response to therapy. Gastric per oral endoscopic pyloromyotomy (GPOEM) has shown an exciting success in treatment of refractory gastroparesis but its clinical impact on different subtypes of gastroparesis is currently unknown. This study aims to evaluate clinical responses of GPOEM based on etiology of gastroparesis. Methods: This retrospective cohort study was conducted in patients with refractory gastroparesis who underwent GPOEM. Symptoms and quality of life were scored using Gastroparesis Cardinal Symptom Index (GCSI) and a short-form 36 questionnaire (SF36) before and after the procedure at 1, 6, and 12-month. Gastric emptying scintigraphy (GES) was obtained at baseline and at 8 weeks. Comparative analysis of clinical outcomes was performed. Results: 12 patients with diabetic gastroparesis (DG), 12 patients with idiopathic gastroparesis (IG), and 5 patients with post-surgical gastroparesis (PG) were included. There was no statistically significant difference in baseline disease severity across all group, measured by GCSI (F=0.04; p=0.96), SF36 (F=0.24; p=0.79), and GES (F=1.48; p=0.28). DG cohort had significantly longer duration of the disease (6.7+/-3.8 years), compared to IG (t=1.92; p=0.03) and PG group (t=-2.2; p=0.01). Overall, 76.9% of patients achieved clinical response. All group had statistically significant improvement in GES, GCSI, and SF36. There was no significant difference on degree of improvement of GES (F=0.3; p=0.74), GCSI (F=0.09; p=0.91), and SF36 (F=1.14; p=0.33) at 1-month post GPOEM among 3 groups. There was no significant difference on the improvement of GCSI and SF36 between DG and IG at both 6-month (t=0.18; p=0.85 and t=-1.4; p=0.18) and 12-month post procedure (t=-0.5; p=0.6 and t=0.58; p=0.58). Subgroup analyses of clinical responses on each primary symptom of nausea, early satiety, bloating, and pain did not show any significant differences among DG, IG, and PG cohort. Conclusion: GPOEM resulted in improved GSCI and quality of life that sustained throughout a 12-month period in all subtype of gastroparesis, including DG, IG and PG, with a similar degree of improvement. Despite a greater decrease in nausea and early satiety, compared to bloating and pain, they did not reach statistical significance in subgroup analyses. Larger studies are warranted to determine factors associated with favorable outcomes.Figure: Improvement of GCSI after GPOEM in each subtype of gastroparesis;GCSI: gastroparesis cardinal symptoms index; GPOEM: gastric per oral endoscopic pyloromyotomy.Figure: Improvement of quality of life after GPOEM in each subtype of gastroparesis;SF36: Short form 36; GPOEM: gastric per oral endoscopic pyloromyotomy.Figure: Improvement of GES after GPOEM in each subtype of gastroparesis;GES: gastric emptying scintigraphy; GPOEM: gastric per oral endoscopic pyloromyotomy; DG: diabetic gastroparesis; IG: idiopathic gastroparesis; PG: post-surgical gastroparesis.

Comparative Analysis of Clinical Outcomes for HCV Patients Treated With Oral Antivirals in Specialty Clinic versus Primary Care Physician Clinic

Comparative Analysis of Clinical Outcomes for HCV Patients Treated With Oral Antivirals in Specialty Clinic versus Primary Care Physician Clinic

Comparative analysis of clinical outcomes between zero-profile implant and cages with plate fixation in treating multilevel cervical spondilotic myelopathy: A three-year follow-up

ObjectivesThis study aimed to figure out three-year clinical outcomes and complications of ACDF with Zero-p in treating multilevel cervical spondylotic myelopathy (MCSM) by comparing with plate fixation. Clinical materials and methodsPatients with MCSM caused by degenerative disc herniation only were recruited from April 2010 to December 2010. According to the surgical procedures, the patients were divided into two groups at random, the plate group and Zero-P group. The data was collected before surgery and at three-year follow-up. Clinical parameters, including Japanese orthopedic association (JOA) score, neck disabled index (NDI) were evaluated. Cervical segmental lordosis was calculated and fusion in each level was assessed on lateral radiographs. The Bazaz’s criterion and the short Swallowing and Quality of Life (SQOL) questionnaires were used to evaluate the dysphagia incidence and severity respectively. The presence of ALOD was observed and recorded on lateral radiographs. ResultsA total of 72 patients (46 men and 26 women) were recruited. The mean age at operation was 52.9±7.9years, ranged from 43 to 69 years. There was no significant difference between two groups preoperatively in age, sex, operative levels, JOA, NDI, cervical lordosis, dysphagia incidence, SQOL and ALOD incidence. JOA, NDI and cervical lordosis improved postoperatively and postoperative SQOL got restitution in both groups. However, no difference was detected. There were 7 patients with ALOD in the plate group after surgeries while there was only 1 patient in Zero-P group. The difference of AOLD incidence between them was significant. Of the 7 patients with ALOD in the plate group, 4 patients developed ALOD in cranial level, 2 in caudal level and 1 in both levels. The patient in Zero-P group developed ALOD in caudal level. ConclusionBased on the three-year follow-up, we could not conclude that Zero-P was superior to plate fixation in clinical outcomes such as neurological results, cervical lordosis, fusion rate and the incidence and severity of dysphagia in treating MCSM. However, it had the advantage of reducing ALOD incidence which tended to happen in ACDF with plate fixation.

Laparoscopic versus Open Distal Pancreatectomy: Comparative Analysis of Clinical Outcomes at a Single Institution

Background: Distal pancreatectomy (DP) is a standard operation for many pancreatic diseases located to the left of the superior mesenteric vein. Advances in technology have made laparoscopic distal pancreatectomy (LDP) a safe and feasible procedure. In this study, we reviewed our experience with LDP and compared with open distal pancreatectomy (ODP) for the management of benign and malignant lesions. Materials and Methods: A retrospective review of medical records of 93 patients subjected to a DP (ODP=36; LDP=57) for pancreatic tumors between 2001-2015 in the Department of Digestive Surgery of Pontificia Universidad Catolica de Chile. In each patient clinical and surgical characteristic, postoperative evolution and histopathologic examination was analyzed. Results: LDP was associated with significantly less operative blood loss (300 ml vs. 50 ml; p=0.007), higher spleen preservation rate (52.6% vs. 19.2%; p=0.002) and shorter hospital stay (5 days vs. 8 days; p<0.001). There were no significant differences in the incidence of postoperative complications between the two groups Conclusions: LDP is a safe and feasible procedure for DP resections. LDP offers advantages over ODP in terms of reduction of operative blood loss, higher spleen preservation rate and shorter hospital stay.

Comparative Analysis of Clinical Outcome in Penetrating Keratoplasty Using Domestic or Imported Cornea

서울대학교 의과대학 안과학교실, 서울대학교병원 의생명연구원 인공안구센터 안면역각막재생연구실, 순천향대학교 의과대학 구미병원 안과학교실 Department of Ophthalmology, Seoul National University College of Medicine, Seoul, Korea Laboratory of Ocular Regenerative Medicine and Immunology, Seoul Artificial Eye Center, Seoul National University Hospital Biomedical Research Institute, Seoul, Korea Department of Ophthalmology, Soonchunhyang University Gumi Hospital, Soonchunhyang University College of Medicine, Gumi, Korea

Comparative Analysis of Clinical Outcomes and Complications in Patients With Degenerative Scoliosis Undergoing Primary Versus Revision Surgery

Retrospective cohort analysis of prospectively collected data. To compare clinical outcomes and postoperative complications in patients with lumbar degenerative scoliosis who underwent primary (P) versus revision (R) surgery. Revision surgery for spinal deformity is technically challenging and may be associated with greater risks of complications and inferior clinical outcomes. There is a paucity of data in the literature comparing primary versus revision surgery in patients with degenerative scoliosis with respect to their clinical outcomes and complications. An analysis of 84 consecutive patients with degenerative scoliosis who underwent primary versus revision surgery between 2002 and 2010 with a minimum 2-year follow-up was performed. There were 53 patients in the primary group and 31 in the revision group. The average number of previously operated levels in the revision group was 3.5 ± 2.6. Mean age at surgery, sex, and body mass index were similar between the 2 groups, as well as comorbidities and postoperative complication rates (P > 0.05). Although a greater preoperative coronal imbalance was noticed in the revision group (P: 2.5 cm vs. R: 4.8 cm, P = 0.022), the final radiographical measures were comparable between the 2 groups. At 2-year follow-up, Oswestry Disability Index and visual analogue scale scores improved significantly in both groups compared with preoperatively (P < 0.001). The improvement in scores of Oswestry Disability Index and visual analogue scale preoperatively to final follow-up was similar between the 2 groups (P > 0.05). Revision patients achieved the same radiographical and clinical outcomes as primary patients. The complication rates were similar between primary and revision patients. Revision patients benefit from surgery just as much as primary patients at 2-year follow-up.

The Evolution of Accelerated Partial Breast Irradiation: Comparative Analysis of Clinical Outcomes with Interstitial vs Balloon-Based Treatment

The Evolution of Accelerated Partial Breast Irradiation: Comparative Analysis of Clinical Outcomes with Interstitial vs Balloon-Based Treatment

Commentary: No comparison: conservative management of painful spontaneous osteoporotic compression fractures is the way to go

<h3>Commentary on</h3> Lee HM, Park SY, Lee SH, et al. Comparative analysis of clinical outcomes in patients with osteoporotic vertebral compression fractures (OVCFs): conservative treatment versus balloon kyphoplasty. Spine J 2012;12:998–1005 (<i>in this issue</i>).

Comparative analysis of clinical outcomes in patients with osteoporotic vertebral compression fractures (OVCFs): conservative treatment versus balloon kyphoplasty

Most osteoporotic vertebral compression fractures (OVCFs) can be treated conservatively. Recently, kyphoplasty has become a common treatment for painful osteoporotic compression fractures and has shown numerous benefits, such as early pain control and height restoration of the collapsed vertebral body. In spite of being a simple procedure, numerous complications related to kyphoplasty have been reported. Moreover, there is limited evidence to support its superiority. To compare the clinical outcomes of patients with OVCF according to different treatment modalities and identify clinical risk factors related to failure of conservative treatment of OVCF. A prospective study consisting of a review of case report forms. PATIENTS SAMPLE: We prospectively enrolled 259 patients who had one or two acute painful OVCFs confirmed by magnetic resonance imaging. All patients were treated conservatively in the initial 3 weeks. Kyphoplasty was performed in 91 patients who complained of sustained back pain and disability in spite of conservative treatment for the initial 3 weeks. Pain score using visual analog scale (VAS) and the Oswestry Disability Index (ODI). Participants were stratified according to age, sex, level and number of fractures, bone mineral density, body mass index (BMI), collapse rates, and history of spine fractures. Pain scores using VASs were assessed at 1 week and at 1, 3, 6, and 12 months. A total of 259 patients were enrolled, and 231 patients (82 of 91 patients in the kyphoplasty group [KP] and 149 of 168 patients in the conservative treatment group) completed the 1-year follow-up. About 65% of patients were treated successfully with conservative treatment. Risk factors for failure of 3 weeks of conservative treatment were older age (older than 78.5 years), severe osteoporosis (t score less than -2.95), overweight (BMI more than 25.5), and larger collapse rates (more than 28.5%). There were significant reductions in VAS and ODI scores in both groups at each follow-up assessment. At the first month, better clinical results were observed in KP. However, there were no significant differences in outcome measures between the two groups at 3, 6, or 12 months. Thirteen subsequent compression fractures (five in KP and eight in the conservative treatment group) occurred during the 1-year follow-up period. Both treatments of OVCF showed successful clinical results at the end of the 1-year follow-up period. Kyphoplasty showed better outcomes in the first month only. Given these results, prompt kyphoplasty should not be indicated in the case of a patient with OVCF that has no risk factors for failure with conservative treatment. Rather, a trial of conservative, 3-week treatment would be beneficial.

Comparative Analysis of Clinical Outcome and Complications in Primary Versus Revision Adult Scoliosis Surgery

A retrospective case comparison study. We compared clinical outcome and complications in adult patients who underwent primary (P) versus revision (R) scoliosis surgery. There is a paucity of data comparing P versus R adult scoliosis patients with respect to their complication rates and clinical outcome. Assessment of 250 consecutive adult patients who underwent P versus R surgery for idiopathic or de novo scoliosis between 2002 and 2007, with a minimum 2-year follow-up, was performed. There were 126 patients in the P group and 124 in the R group. Mean age at surgery (P = 51.2 vs. R = 51.6 years, P = 0.79), length of follow-up (P = 3.6 vs. R = 3.6 years, P = 0.94), comorbidities (P = 0.43), and smoking status (P = 0.98) were similar between the 2 groups. Body mass index (P = 25.5 vs. R = 27.4 kg/m, P = 0.01), number of final instrumented levels (P = 10.5 vs. R 12.1 levels, P = 0.00), fusion to the sacrum (P = 61.0% vs. R = 87.1%, P = 0.00), osteotomy (P = 14.3% vs. R = 54.9%, P = 0.00), length of surgery (P = 6.5 vs. R = 8.2 hours, P = 0.00), and estimated blood loss (P = 1072.1 vs. R = 1401.3 mL, P = 0.05) were different. Primary patients had significantly lower overall complications than revision patients (P = 45.2% vs. R = 58.2%, P = 0.042). Primary patients reported significantly higher preoperative and final clinical outcome measures in function, pain, and subscore SRS domains and ODI compared with revision patients (all P < 0.05). Patients older than 60 years of age, however, reported similar SRS and ODI scores between the 2 groups. The extent of surgical benefit patients received, that is, final minus preoperative score, was similar in all categories between the 2 groups. Adult patients undergoing primary scoliosis surgery had significantly lower overall complications compared with revision patients. Primary patients reported higher preoperative and final clinical outcome measures than revision patients, although this difference disappeared in older patients. The benefit of surgery was similar between the 2 groups.

Comparative Analysis of Clinical Outcomes Obtained With a New Diffractive Multifocal Toric Intraocular Lens Implanted Through Two Types of Corneal Incision

To analyze and compare the clinical outcomes obtained after cataract surgery with the implantation of a new multifocal toric intraocular lens (IOL) using two different types of corneal incision. Retrospective study including 64 eyes of 35 patients who underwent surgery with implantation of the AT LISA 909M multifocal toric IOL (Carl Zeiss Meditec) in 2 different ophthalmologic centers using different criteria for corneal incision size: sub-1.8 mm (micro-incision surgery [MICS] group) and 2.2 mm (mini-incision group). Visual, refractive, and corneal topographic outcomes were evaluated during 6-month follow-up. Additionally, refractive astigmatic changes were analyzed using the Alpins vectorial method. Significant reductions of refractive sphere and cylinder were observed postoperatively (P<.03), with associated visual improvements for near and distance (P<.01) in both groups. Mean postoperative magnitudes of difference vector, torque, and magnitude of error in the overall sample were 0.52±0.36 diopters (D), 0.36 ± 0.36 D, and 0.08 ± 0.38 D, respectively. A mean overcorrection of 4% in refractive astigmatism was found. Mean angle of error was 0.37± 5.50° and -4.51±13.16° for the MICS and mini-incision groups, respectively (P=.09). Significant positive correlations were found between the magnitudes of torque and difference vector (r=0.78, P<.01) as well as between the magnitude of torque and absolute angle of error (r=0.76, P<.01). Implantation of the AT LISA toric IOL using corneal incisions <2.2 mm provides excellent predictability for astigmatic correction.

Comparative analysis of radiofrequency ablation and surgical resection for colorectal liver metastases

PurposeTo evaluate the comparative therapeutic efficacy of radiofrequency ablation (RFA) and hepatic resection for the treatment of colorectal liver metastasis (CRLM).MethodsBetween 1996 and 2008, 177 patients underwent RFA, 278 underwent hepatic resection and 27 underwent combination therapy for CRLM. Comparative analysis of clinical outcomes was performed including number of liver metastases, tumor size, and time of CRLM.ResultsBased on multivariate analysis, overall survival (OS) correlated with the number of liver metastases and the use of combined chemotherapy (P < 0.001, respectively). Disease-free survival (DFS) also correlated with the number of liver metastases (P < 0.001). In the 226 patients with solitary CRLM < 3 cm, OS and DFS rates did not differ between the RFA group and the resection group (P = 0.962 and P = 0.980). In the 70 patients with solitary CRLM ≥ 3 cm, DFS was significantly lower in the RFA group as compared with the resection group (P = 0.015).ConclusionThe results indicate that RFA may be a safe alternative treatment for solitary CRLM less than 3 cm, with outcomes equivalent to those achieved with hepatic resection. A randomized controlled study comparing RFA and resection for patients with single small metastasis would help to determine the most efficient treatment modalities for CRLM.

Comparative Analysis of Clinical Outcomes in Patients with Osteoporotic Vertebral Compression Fractures: Conservative Treatment vs. Kyphoplasty

Almost OVCF can be treated conservatively. Recently, kyphoplasty has become a common treatment for painful osteoporotic compression fractures.

Comparative Analysis of Clinical Outcome and Perioperative Complications in Primary vs. Revision Adult Scoliosis Surgery

Comparative Analysis of Clinical Outcome and Perioperative Complications in Primary vs. Revision Adult Scoliosis Surgery

Comparative analysis of clinical outcomes for laparoscopic distal pancreatic resection and open distal pancreatic resection at a single institution

Despite recent advances in laparoscopic pancreatic surgery, few studies have compared laparoscopic distal pancreatic resection (LDPR) with open distal pancreatic resection (ODPR). This study aimed to compare clinical outcomes for LDPR and ODPR performed at a single institution. For this study, 93 patients with benign pancreatic disease underwent LDPR, and 35 patients with benign pancreatic disease underwent ODPR. Patient demographic characteristics, operative times, perioperative complications, length of hospital stay, and return to normal diet were compared retrospectively between the two groups. The LDPR and ODPR groups had the same demographic characteristics. The median operative time was 195 min in the LDPR group and 190 min in the ODPR group (p>0.05). The rate of spleen preservation was higher in the LDPR group (40.8%) than in the ODPR group (5.7%) (p<0.05) No operative mortality occurred in either group. The overall complication rate was 24.7% in the LDPR group and 29% in the ODPR group (p>0.05). The rate of pancreas-related complications was 11.8% in the LDPR group and 17.2% in the ODPR group (p>0.05). Pancreatic fistula developed in 8.6% of the LDPR group and in 14.3% of the ODPR group (p>0.05). Bowel movement return to normal and resumption of normal diet were achieved 2.8+/-1.3 days after the operation in the LDPR group and 4.5+/-1.6 days after the operation in the ODPR group (p<0.05). The median duration of hospital stay was 10 days for the LDPR group, which was significantly shorter than the 16 days for the ODPR group (p<0.01). The use of LDPR for benign lesions of the distal pancreas is feasible and safe. The LDPR procedure is associated with operative times and complication rates similar to those for ODPR, but LDPR has the advantages of an earlier return to normal bowel movements and normal diet and shorter hospital stays than ODPR.

Comparative Analysis of Clinical Outcomes between Unrelated Donor Peripheral Blood Stem Cell Transplantation and Bone Marrow Transplantation for Leukemia.

Objective To evaluate hematopoietic reconstitution, immune reconstitution, infection, incidence of graft-versus-host disease (GVHD) and other complications between unrelated donor peripheral blood stem cell (PBSC) transplantation and bone marrow (BM) transplantation.Methods The clinical results in 21 patients receiving a PBSC graft mobilized by granulocyte colony stimulating factor (G-CSF) from unrelated donors were compared to 32 patients receiving unrelated BM transplants.Results The PBSC graft contained significantly more nucleated cells (P=0.000), and resulted in a significantly shorter time-to-neutrophil (12.43±3.67 versus 16.16±2.99 days) and platelet engraftment (14.67±6.19 versus 21.23±8.25 days), compared to the BM group (P=0.000, 0.003, respectively). T cell reconstitution between the two groups differed little after transplantation. The incidences of early-stage infection were 42.86% and 53.13% (not significant [NS]) in the PBSC and BM groups, respectively. Probabilities of acute graft-versus-host disease (aGVHD) were 61.90% and 71.88% (NS), of grades III to IV aGVHD 23.81% and 15.63% (NS) and of chronic GVHD 47.06% and 43.48% (NS) in the PBSC and BM groups, respectively. The probabilities of relapse were 6.90% and 12.50% (NS) in the PBSC and BM groups, respectively. The 2-year disease free survival (DFS) rates of the two groups were (50.14±12.00) % and (59.81±8.99) %( NS), respectively.Conclusion G-CSF-mobilized PBSCs engraft rapidly in unrelated donor recipients compared to conventional BM, but T cell reconstitution and the incidence of infection between the two groups differed little. There were no significant differences of the incidence and severity of aGVHD and cGVHD, and 2-year DFS rates between the two groups.

31: Comparative Analysis of Clinical Outcome in Patients Undergoing Radical Cystectomy in Different Age Groups

You have accessJournal of UrologyDiscussed Poster, Saturday, May 20, 2006, 1:00 - 4:00 pm1 Apr 200631: Comparative Analysis of Clinical Outcome in Patients Undergoing Radical Cystectomy in Different Age Groups Vishwanath S. Hanchanale, John E. McCabe, and Pradip M. Javle Vishwanath S. HanchanaleVishwanath S. Hanchanale More articles by this author , John E. McCabeJohn E. McCabe More articles by this author , and Pradip M. JavlePradip M. Javle More articles by this author View All Author Informationhttps://doi.org/10.1016/S0022-5347(18)32298-5AboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissionsReprints ShareFacebookLinked InTwitterEmail "31: Comparative Analysis of Clinical Outcome in Patients Undergoing Radical Cystectomy in Different Age Groups." The Journal of Urology, 175(4S), p. 11 © 2016 by American Urological AssociationFiguresReferencesRelatedDetails Volume 175Issue 4SApril 2006Page: 11 Advertisement Copyright & Permissions© 2016 by American Urological AssociationMetricsAuthor Information Vishwanath S. Hanchanale More articles by this author John E. McCabe More articles by this author Pradip M. Javle More articles by this author Expand All Advertisement Loading ...

Age-related variations in the use of axillary dissection in breast cancer: a comparative analysis of clinical outcomes in women treated with vs without axillary dissection

Purpose: Axillary dissection (AD) provides staging information and guides adjuvant treatment for patients with breast cancer. The impact of AD on breast cancer survival is unclear. This study examines age-related variations in the use of AD and analyzes survival in women with T1-T2 breast cancer according to age and AD use.