Study Objective: To compare the outcomes of patients undergoing robotic assisted total laparoscopic hysterectomy (RH) to those undergoing other minimally invasive methods of hysterectomy (MIH). Design: Retrospective cohort study. Setting: Henry Ford Health System’s community based teaching hospitals. Patients: 228 patients underwent RH or non-robotic MIH for benign indications, at one of two hospitals, between January 2007 andMarch 2010. Intervention: Scheduled RH or MIH, which included total laparoscopic hysterectomy (TLH), laparoscopic assisted vaginal hysterectomy (LAVH) or vaginal hysterectomy (VH). Measurements and Main Results: Age, race, body mass index (BMI), procedure duration, estimated blood loss (EBL), peri-operative hemoglobin change, uterine weight, length of hospital stay (LOS), and all immediate and delayed complications were collected from patient electronic medical records. These factors were compared between RH and MIH patients. 121 RH cases and 107 MIH cases (n=20 VH, n=46 LAVH, n=41 TLH) were included. There were no differences in age (median 45 RH, 46 MIH) or race between groups. While not statistically significant,, there was a greater percentage of obese patients (BMI>30) in the RH group (52.6% versus 46.7%). RH patients had significantly larger uteri (p=0.04; percent R500g: RH, 13.9%; MIH, 4%). MIH patients had significantly greater EBL than RH patients (p\0.001) with a 75 ml difference in median EBL (150 ml versus 75 ml). This was confirmed by a significant difference in hemoglobin change (p=0.048) between groups. Although RH patients had longer procedure durations than MIH patients (p=0.004), the difference in medians was only 20 minutes (172 minutes versus 152 minutes). There were no statistically significant differences in LOS (p=0.24), overall (p=0.64), major (p=0.15), or minor (p=0.34) complication rates for RH and MIH procedures. Conclusion: RH has comparable outcomes to other methods of MIH without increased risk. RH may help overcome the usual limiting factors of large uterine size or high BMI without increasing blood loss, length of stay, or complications.