Communities In Wuhan Research Articles

Imaging, biomarkers, and vascular cognitive impairment in China: Rationale and design for the VICA study.

Vascular cognitive impairment (VCI) is highly heterogeneous, with unclear pathogenesis. Individuals with vascular risk factors (VRF), cerebral small vessel disease (CSVD), and stroke are all at risk of developing VCI. To address the growing challenges posed by VCI, the "Vascular, Imaging and Cognition Association of China" (VICA) was established. VICA aims to recruit 10,000 participants, including 2000 with VRF, 3000 with CSVD, and 5000 stroke patients, to form a nationwide multicenter cohort. The study integrates clinical, neuroimaging, and multi-omics data to better understand VCI heterogeneity, improve disease prediction, and ensure timely diagnosis. VICA has screened 2045 eligible VRF participants from six communities in Wuhan, Shanghai, and Taizhou, along with 602 CSVD and 1269 stroke patients from 135 hospitals nationwide. Baseline enrollment and follow-up work are still ongoing. Establishing a high-quality longitudinal cohort is crucial for understanding VCI pathogenesis and developing novel markers for early screening and diagnosis. Establish a large-scale prospective longitudinal cohort comprising 10,000 participants, focusing on the high-risk population of vascular cognitive impairment (VCI) in China. Establish a nationwide three-tier medical network, make full use of resources, and achieve extensive enrollment of patients with cerebral small vessel disease and stroke patients. Utilize multimodal imaging and biomarkers to lay the foundation for constructing more-precise risk models. Introduce eye movement and gait analysis as new methods for assessing cognitive function. Use positron emission tomography to further investigate the interaction between vascular factors and neurodegeneration.

Evaluation of Aging-Friendly Public Spaces in Old Urban Communities Based on IPA Method—A Case Study of Shouyi Community in Wuhan

In recent years, the aging population in Chinese cities has become increasingly severe. In 2021, the proportion of people aged 65 and above in Wuchang District, Wuhan reached 24.38%, indicating a deeply aging society. Consequently, the importance of studying aging-friendly public spaces in communities is becoming more prominent. This research was conducted based on survey data of outdoor spaces in Shouyi Community, Shouyi Road. Factor analysis and IPA were used to assess the satisfaction and importance of elderly residents’ satisfaction. The primary renovation factors identified include route organization, site height difference protection, barrier-free design, plant color matching, plant configuration, and landscape features, followed by spatial continuity, lighting, microclimate, and rest facilities layout. These analyses effectively identified public factors and prioritize the aging-friendly renovation of public spaces in old communities. In the renovation of old communities in Wuhan, safety is the primary renovation factor for aging-friendly communities. Improving site height difference protection and barrier-free facilities significantly enhances residents’ satisfaction. The aesthetic improvement of outdoor spaces is the second renovation factor, indicating that the elderly increasingly value the aesthetic aspect of spaces. Although accessibility of community public spaces is the third renovation factor, route organization at the criterion level has the highest priority. Road traffic and parking difficulties are also key factors in the renovation of old communities.

Research on the Elastic Design of Public Space in Old Communities in Wuhan Under the Guidance of Healthy China

Research on the Elastic Design of Public Space in Old Communities in Wuhan Under the Guidance of Healthy China

3-year outcomes of discharged survivors of COVID-19 following the SARS-CoV-2 omicron (B.1.1.529) wave in 2022 in China: a longitudinal cohort study

There is a paucity of data on the natural trajectory of outcomes in survivors of COVID-19 beyond 2 years after symptom onset, and no evidence exists on the effect of re-infection in people with long COVID symptoms. We aimed to investigate the 3-year health outcomes of COVID-19 survivors and the effect of omicron re-infection. In this single-centre, longitudinal cohort study, we recruited participants with confirmed COVID-19 who were discharged from the Jin Yin-tan hospital in Wuhan, China, between Jan 7 and May 29, 2020. Participants completed three follow-up visits at 6 months (June 16 to Sept 13, 2020), 1 year (Dec 16, 2020, to Feb 7, 2021), and 2 years (Nov 16, 2021, to Jan 10, 2022) since symptom onset (reported previously). At 1-year follow-up, community controls without a history of SARS-CoV-2 infection were recruited from two communities in Wuhan and at 2 years were matched (1:1) with survivors of COVID-19 who underwent pulmonary function tests. We did a 3-year follow-up from Feb 23, 2023, to April 20, 2023, after the omicron (B.1.1.529) wave in winter, 2022. All eligible survivors of COVID-19 and community controls matched at 2-year follow-up were invited to the outpatient clinic at the hospital to complete several face-to-face questionnaires, a 6-min walking test (6MWT), and laboratory tests. A subgroup of survivors of COVID-19 identified by stratified sampling on the basis of disease severity scale score during hospitalisation and community controls underwent pulmonary function tests. Survivors of COVID-19 who received high-resolution CT and showed abnormal lung images at 2-year follow-up were invited for another assessment. We identified participants with and without long COVID at 2 years. The primary outcomes were sequelae symptoms, omicron infection, lung function, and chest imaging at the 3-year follow-up. Of 1359 COVID-19 survivors who completed 2-year and 3-year follow-up, 728 (54%) had at least one sequelae symptom at 3 years after symptom onset and before omicron infection, mainly mild to moderate severity. During the omicron wave, participants with long COVID at 2 years had a significantly higher proportion of re-infection (573 [76%] of 753 vs 409 [67%] of 606 without long COVID; p=0·0004), pneumonia (27 [5%] of 568 vs seven [2%] of 403; p=0·012). 3 months after omicron infection, 126 (62%) of 204 survivors with long COVID at 2 years had newly occurring or worse symptoms, which was significantly higher than the proportion in the non-long COVID group (85 [41%] of 205; p<0·0001) and community controls (81 [40%] of 205; p<0·0001), and not significantly different between COVID-19 survivors without long COVID and matched community controls (85 [41%] of 205 vs 81 [39%] of 206; p=0·66). Re-infection was a risk factor for dyspnoea (odds ratio 1·36 [95% CI 1·04 to 1·77]; p=0·023), anxiety or depression (OR 1·65 [1·24 to 2·20]; p=0·0007), EuroQol visual analogue scale score (β -4·51 [-6·08 to -2·95]; p<0·0001), but not for reduced daily activity (0·72 [0·38 to 1·37]; p=0·32) at 3 years. Lung function of survivors at 3 years was similar to that of matched community controls. We found irregular line, traction bronchiectasis, subpleural lines and ground glass opacity at 3 years, but the volume ratio of lung lesion to total lung was only 0·2-0·3%. Most long COVID symptoms at 3 years were mild to moderate, with lung function recovering to levels of matched controls. Survivors with long COVID had a higher proportion of participants with re-infection and newly occurring or worse symptoms 3 months after omicron infection than those without long COVID. Re-infection had increased symptom occurrence but not increased reduced daily activity. Although the organ function of survivors of COVID-19 recovered over time, those with severe long COVID symptoms, abnormal organ function, or limited mobility require urgent attention in future clinical practice and research. Chinese Academy of Medical Sciences Innovation Fund for Medical Sciences, National Natural Science Foundation of China.

A randomized, prospective, active-controlled study comparing intramuscular long-acting paliperidone palmitate versus oral antipsychotics in patients with schizophrenia at risk of violent behavior

ObjectivePaliperidone palmitate (PP) is an effective long-acting antipsychotic injection, but its impact on the behavior of schizophrenia patients with dangerous tendencies requires further investigation. This study aims to explore the effects of long-term antipsychotic treatment on this population in the community. MethodsThis 49-week, randomized controlled trial was conducted across 21 communities in Wuhan and enrolled 134 schizophrenia patients at risk for violent behavior. With a fixed block size of 10, participants were randomly assigned to receive either intramuscular PP 1-month formulation (PP1M) or oral antipsychotic medication (OAP) at a 1:1 ratio. Changes in patients' risk for violent/aggressive behavior, family burden, social, and cognitive functioning were measured using VRAPP, MOAS, PANSS, FBS, PSP, and RBANS scales from baseline to endpoint. Longitudinal data from multiple repeated measures were analyzed using linear mixed-effects models. ResultsThe study protocol was completed by 77.6% of the patients overall. Significant improvements were observed in the risk assessment scores, MOAS total score, PANSS total score, PSP total score, and FBS total score of patients in the PP1M group from baseline to the end of treatment (all P < 0.05). Importantly, compared to patients in the OAP group, the improvements in these measures were also significantly greater in the PP1M group. Commonly observed AEs, such as hyperprolactinemia (70.3% vs. 62.65%) and muscle tension (45.3% vs. 57.8%), were considered to be the PP-related AEs. Nonetheless, the differences between the two groups did not reach statistical significance, and no new safety concerns emerged. ConclusionsOur study suggests that PP long-acting injection (LAI) is a safe and effective treatment option for community-dwelling schizophrenia patients with impulsive violence and risky behaviors.

Exploring the spatial pattern of community urban green spaces and COVID-19 risk in Wuhan based on a random forest model

Since 2019, COVID-19 has triggered a renewed investigation of the urban environment and disease outbreak. While the results have been inconsistent, it has been observed that the quantity of urban green spaces (UGS) is correlated with the risk of COVID-19. However, the spatial pattern has largely been ignored, especially on the community scale. In high-density communities where it is difficult to increase UGS quantity, UGS spatial pattern could be a crucial predictive variable. Thus, this study investigated the relative contribution of quantity and spatial patterns of UGS on COVID-19 risk at the community scale using a random forest (RF) regression model based on (n = 44) communities in Wuhan. Findings suggested that 8 UGS indicators can explain 35% of the risk of COVID-19, and the four spatial pattern metrics that contributed most were core, edge, loop, and branch whereas UGS quantity contributed least. The potential mechanisms between UGS and COVID-19 are discussed, including the influence of UGS on residents’ social distance and environmental factors in the community. This study offers a new perspective on optimizing UGS for public health and sustainable city design to combat pandemics and inspire future research on the specific relationship between UGS spatial patterns and pandemics and therefore help establish mechanisms of UGS and pandemics.

Understanding active transportation accessibility's impacts on polycentric and monocentric cities' housing price

Active transportation (AT) accessibility, specifically walking and cycling accessibility, has a significant impact on housing prices and equity. However, the spatial variation of the impacts of both walking and cycling accessibility and the influence of urban structure on housing submarkets are often overlooked in existing studies. This research aims to fill this gap by investigating the impacts of eight types of AT accessibility, inherent and locational attributes on housing prices in polycentric and monocentric cities. Geographically weighted regression models were estimated using housing price data from 3496 communities in Shanghai (a monocentric city) and 1100 communities in Wuhan (a polycentric city), China. The results illustrate the spatially varying impacts of AT accessibility on housing prices and highlight the existence of housing submarkets within cities due to varying factors such as urban structure, job-housing imbalance, consumer demand, public and private investment, and residential self-selection process. These findings provide valuable insights for investing in residential properties and designing policies and projects to improve AT accessibility in a way that promotes equity.

A feasibility study on home-based kyphosis-specific exercises on reducing thoracic hyperkyphosis in older adults

ObjectivesThis study aimed to assess the feasibility of the home-based kyphosis-specific exercises among Chinese older adults with different exercise habits and explore its potential effects on reducing the kyphosis angle and improving physical performance. MethodsA single-group, pre-and post-test design was conducted according to CONSORT 2010 statement: extension for pilot and feasibility trials. A total of 20 participants aged ≥60 with thoracic hyperkyphosis and rehabilitation potential were recruited from four local communities in Wuhan, China. Participants underwent a six-week home-based kyphosis-specific exercises intervention that included warm-up, muscle strengthens, spinal alignment, spinal mobility and flexibility, and cool down five sections (22 exercises). The intervention involved seven 1-h group classes and 35 times daily home practice with identical content. At pre- and post-intervention, the participants' kyphosis angle in two standing postures, static balance, dynamic balance, cardiopulmonary function, dynamic gait assessment, pain, and self-image were assessed and compared. Feasibility was assessed by group class attendance, home practice adherence, and participant evaluations. ResultsAll participants completed group classes and >75% home practice. Post-intervention, the participant’s kyphosis angle in relaxed and best-standing postures was changed by −12.0° (−15.5°, −4.0°) (Z = − 3.98, P < 0.001）and −10.0° (−14.0°, −5.3°) (Z = −3.79, P < 0.001), respectively. In addition, participants had significantly less pain (P < 0.001), better self-image (P < 0.001), and improved performance in five physical assessments (P < 0.01). Different pre-intervention hyperkyphosis angle and daily physical activity did not affect intervention effects. Most participants considered the interventional exercise as moderate intensity and satisfactory. ConclusionsHome-based kyphosis-specific exercises showed the possibility of being a feasible intervention. And it was advantageous to reducing the kyphosis angle and improving physical performance.

Demand for Community Medical-Nursing Combined Services among the Empty-Nest Elderly in China: A Qualitative Study

Currently, the number of empty-nest elders in China is rapidly increasing, and their overall health situation is not optimistic. The Chinese government has developed a series of policies to promote the community medical-nursing combined model to meet the health and pension care needs of elderly individuals. The demand for community medical-nursing combined services among empty-nest elders plays a decisive role in providing these services and must be fully recognized before these services are offered. However, only a few quantitative studies have focused on the demand for community medical-nursing combined services, and these studies failed to capture the complexity and dynamic nature of this demand. To address this research gap, this study innovatively conducted a descriptive and qualitative study to explore the demand for these services. Following the principle of data saturation, 14 empty-nest elders from communities in Wuhan, Hubei Province, were recruited using the purposive sampling method. Semistructured interviews were used to collect qualitative data. The inductive content analysis approach was used to analyze the data. The results revealed that Chinese empty-nesters’ demand for community medical-nursing combined services was diverse and specific and comprised three themes (basic elderly care services, medical and nursing services, and psychospiritual support services), with fifteen subthemes. This study provides insights into the unique demand and implementation strategies for community medical-nursing services among empty-nest elders in China. Recommendations to enhance the intelligent elderly care system, infrastructure construction, and elderly care talent in the future provision of services for this particular group of people are provided.

A dual-task gait test detects mild cognitive impairment with a specificity of 91.2.

Mild cognitive impairment (MCI) is a valuable intervention window in the progress of senile dementia, but the question of how to easily and conveniently detect MCI in the community remains unanswered. Gait performance reflects cognitive function, but how to reliably detect MCI through gait testing is still being explored. To develop a dual-task gait testing method that could reliably detect MCI in the community. A cross-sectional diagnostic study was conducted in 111 older adults (mean age = 72.14 ± 6.90 years) from five communities in Wuhan, China. A novel dual-task gait testing method, walking while identifying animals in pictures (AniP-DT gait test), was developed. The participants were classified into MCI or cognitively intact based on their performance on the Montreal Cognitive Assessment Scale (MoCA). Gait performance was assessed using both single-task and the AniP-DT gait test. Multiple linear regression and binary logistic regression were used to model the association between gait speed and cognitive status, and receiver operating characteristic (ROC) curve analysis was used to assess the discrimination ability. Compared to the cognitively intact group, the gait speed of the MCI group was lower in both single-task and the AniP-DT gait tests. The gait speed of the AniP-DT gait test was significantly associated with MoCA scores after adjusting the covariates and exhibited good discrimination ability in MCI detection (AUC = 0.814), with a specificity of 91.2%. ROC analysis of the logistic models revealed better discrimination ability of dual-task gait velocity when adjusted with age and years of education (AUC = 0.862). The evidence in this study suggested that the AniP-DT gait test could be an easy and reliable screening tool for MCI in community older adults.

疫情常态化下人工智能提升社区治理效能的现状、困境及路径探研——以武汉市社区为例

疫情常态化下人工智能提升社区治理效能的现状、困境及路径探研——以武汉市社区为例

Flood Risk Assessment and Management in Urban Communities: The Case of Communities in Wuhan

The likelihood and uncertainty of severe rains and flooding in the middle basin of the Yangtze River have grown due to global warming and growing urbanization. A flood risk assessment index system is built based on resilience theory to assess community flood risk in a significantly changing environment, with communities serving as the primary body to manage flood risk in cities. The flood risk level of communities in Wuhan from 2011 to 2020 was assessed using the Analytic Hierarchical Process (AHP) and Dempster–Shafer (DS) evidence theory, utilizing an example of the typical Wuhan community. The findings indicate that: (1) The weight of hazard-causing factors is the largest and has the greatest influence on the risk of flooding in the community. (2) When looking at time series, the risk of hazard-causing factors gradually rises, while the risks associated with systemic governance, protective works, and community vulnerability steadily decline. Building resilient communities and enhancing flood risk management capability should be priorities for the government, local communities, and citizens.

Experiences and expectations of receiving volunteer services among home-based elderly in Chinese urban areas: A qualitative study.

The various complex needs for assistance among home-based older adults have increased dramatically. Thus, it would be advantageous to recruit volunteers with medical knowledge and a better understanding to support and assist the elderly living in urban communities. This study aimed to explore the experiences and expectations of receiving volunteer services among the home-based elderly in Chinese urban areas. DESIGN, SETTINGAND PARTICIPANTS: A descriptive qualitative study was conducted following the Consolidated Criteria for Reporting Qualitative Research (COREQ) guidelines. This study was performed in two communities in Wuhan, Hubei Province. A purposive sampling method, which includes criterion and maximum variation sampling, was used to identify and select a diverse range of participants. Semistructured face-to-face interviews with 20 older adults (aged 62-90 years old) were performed. The conventional content analysis method was used for thematic analysis. Three categories with associated subcategories were identified: experiences of receiving volunteer services including negative and positive experiences; specific needs for volunteer services involving physiological, psychosocial, health-related behavioursand environmental domains; characteristics of expected volunteer services including availability, formats, recipients, providersand service strategies. The volunteer services provided to the home-based elderly were found to be unsatisfactory, and lacking relevance and effectiveness. Due to a lack of family support or difficulty in meeting some high-level needs, the home-based elderly expressed a strong demand for volunteer services involving physiological, psychosocial, health-related behavioursand environmental domains. This finding can provide a basis for developing training plans beneficial to volunteers. Furthermore, the present research clarifies the criteria for selecting volunteers and the necessity of supervising and managing volunteers. Improving the effectiveness and accessibility of urban-community volunteer service may reduce the burden on care institutions and home caregivers while enhancing the quality of life and well-being of the elderly. Developing research questions, study design, management and conductand interpretation of evidence.

Spatial Equity of PM2.5 Pollution Exposures in High-Density Metropolitan Areas Based on Remote Sensing, LBS and GIS Data: A Case Study in Wuhan, China.

In-depth studies have been conducted on the risk of exposure to air pollution in urban residents, but most of them are static studies based on the population of residential units. Ignoring the real environmental dynamics during daily activity and mobility of individual residents makes it difficult to accurately estimate the level of air pollution exposure among residents and determine populations at higher risk of exposure. This paper uses the example of the Wuhan metropolitan area, high-precision air pollution, and population spatio-temporal dynamic distribution data, and applies geographically weighted regression models, bivariate LISA analysis, and Gini coefficients. The risk of air pollution exposure in elderly, low-age, and working-age communities in Wuhan was measured and the health equity within vulnerable groups such as the elderly and children was studied. We found that ignoring the spatio-temporal behavioral activities of residents underestimated the actual exposure hazard of PM2.5 to residents. The risk of air pollution exposure was higher for the elderly than for other age groups. Within the aging group, a few elderly people had a higher risk of pollution exposure. The high exposure risk communities of the elderly were mainly located in the central and sub-center areas of the city, with a continuous distribution characteristic. No significant difference was found in the exposure risk of children compared to the other populations, but a few children were particularly exposed to pollution. Children’s high-exposure communities were mainly located in suburban areas, with a discrete distribution. Compared with the traditional static PM2.5 exposure assessment, the dynamic assessment method proposed in this paper considers the high mobility of the urban population and air pollution. Thus, it can accurately reveal the actual risk of air pollution and identify areas and populations at high risk of air pollution, which in turn provides a scientific basis for proposing planning policies to reduce urban PM2.5 and improve urban spatial equity.

Experiences and challenges faced by community mental health workers when providing care to people with mental illness: a qualitative study

BackgroundMental illness is a major burden of disease worldwide. Community Mental Health Services (CMHS) are key to achieving community-based recovery for people with mental illness. In China, even though the community management of patients with mental illness is improving, the barriers faced by Community Mental Health Workers (CMHWs) are unclear. This study explores the difficulties and challenges in CMHS from the perspective of CMHWs. The results of this study may provide a practical basis for the training of CMHWs.MethodsWe carried out a qualitative study using an empirical phenomenological approach. Nine CMHWs were recruited from nine communities in Wuhan, Hubei Province, using purposive and snowball sampling. Face to face semi-structured in-depth interviews were conducted with them from December 27 to 28, 2019. Interview recordings were converted to text content by Nvivo 11.0 software and analyzed using Colaizzi’s phenomenological method.ResultsThree main themes were identified in this study: 1) Lack of role orientation leads to role ambiguity, 2) Failure to establish a therapeutic trust relationship with patients, and 3) Lack of communication and collaboration with various departments and peers. Seven sub themes were also identified. In these themes, CMHWs emphasized the importance of role clarity, therapeutic trusting relationships, and effective communication and coordination mechanisms.ConclusionAlthough China has made great efforts on the road to improving the quality of CMHS, several salient issues regarding CMHWs must be addressed to optimize the quality of services provided by CMHWs. Community mental health institutions should help CMHWs overcome these difficulties, by maximizing its value and promoting the development of CMHS.

Assessing myocardial infarction severity from the urban environment perspective in Wuhan, China.

Health inequalities are globally widespread due to the regional socioeconomic inequalities. Myocardial infarction (MI) is a leading health problem causing deaths worldwide. Yet medical services for it are often inequitably distributed by region. Moreover, studies concerning MI's potential spatial risk factors generally suffer from difficulties in focusing on too few factors, inappropriate models, and coarse spatial grain of data. To address these issues, this paper integrates registered 1098 MI cases and urban multi-source spatio-temporal big data, and spatially analyses the risk factors for MI severity by applying an advanced interpretable model, the random forest algorithm (RFA)-based SHapley Additive exPlanations (SHAP) model. In addition, a community-scale model between spatio-temporal risk factors and MI cases is constructed to predict the MI severity of all communities in Wuhan, China. The results suggest that those risk factors (i.e., age of patients, medical quality, temperature changes, air pollution and urban habitat) affect the MI severity at the community scale. We found that Wuhan residents in the downtown area are at risk for high MI severity, and the surrounding suburb areas show a donut-shape pattern of risk for medium-to-high MI severity. These patterns draw our attention to the impact of spatial environmental risk factors on MI severity. Thus, this paper provides three recommendations for urban planning to reduce the risk and mortality from severe MI in the aspect of policy implication.

Seroprevalence and dynamics of anti-SARS-CoV-2 antibodies: a longitudinal study based on patients with underlying diseases in Wuhan

BackgroundAssessing the humoral immunity of patients with underlying diseases after being infected with SARS-CoV-2 is essential for adopting effective prevention and control strategies. The purpose of this study is to analyze the seroprevalence of people with underlying diseases and the dynamic change features of anti-SARS-CoV-2 antibodies.MethodsWe selected 100 communities in Wuhan using the probability-proportional-to-size sampling method. From these 100 communities, we randomly selected households according to a list provided by the local government. Individuals who have lived in Wuhan for at least 14 days since December 2019 and were ≥ 40 years old were included. From April 9–13, 2020, community staff invited all selected individuals to the community healthcare center in batches by going door-to-door or telephone. All participants completed a standardized electronic questionnaire simultaneously. Finally, 5 ml of venous blood was collected from all participants. Blood samples were tested for the presence of pan-immunoglobulins, IgM, IgA, and IgG antibodies against SARS-CoV-2 nucleocapsid protein and neutralising antibodies were assessed. During the period June 11–13, 2020 and October 9–December 5, 2020, all family members of a positive family and matched negative families were followed up twice.ResultsThe seroprevalence of anti-SARS-CoV-2 antibodies in people with underlying diseases was 6.30% (95% CI [5.09–7.52]), and that of people without underlying diseases was 6.12% (95% CI [5.33–6.91]). A total of 313 people were positive for total antibodies at baseline, of which 97 had underlying disease. At the first follow-up, a total of 212 people were positive for total antibodies, of which 66 had underlying disease. At the second follow-up, a total of 238 people were positive for total antibodies, of which 68 had underlying disease. A total of 219 participants had three consecutive serum samples with positive total antibodies at baseline. The IgG titers decreased significantly with or without underlying diseases (P < 0.05) within the 9 months at least, while the neutralizing antibody titer remained stable. The titer of asymptomatic patients was lower than that of symptomatic patients (baseline, P = 0.032, second follow-up, P = 0.018) in the underlying diseases group.ConclusionOur research focused on the serological changes of people with and without underlying diseases in a state of single natural infection. Regardless of the underlying diseases, the IgG titer decreased significantly over time, while there was no significant difference in the decline rate of IgG between with and without underlying diseases. Moreover, the neutralizing antibody titer remained relatively stable within the 9 months at least.

Study of residents’ willingness to construct community gardens in the post-epidemic era

Following the outbreak of the COVID-19 pandemic, people who had experienced social isolation during the epidemic became more concerned about the function of public open spaces in their communities. In developing China, community gardens have not been included in the urban planning system. This study explores whether community residents support the construction of community gardens on public land for collective gardening activities and the reasons for the formation of their willingness. The subjects of this study are residents of three urbanized residential communities in Wuhan, Hubei Province. Questionnaires were distributed in the communities via the internet to assess residents’ willingness to build community gardens. Three hundred eighty-two completed and valid questionnaires were collected. Descriptive statistics and chi-square tests were used to evaluate the categorical variables. The results showed that 82.5% of respondents expressed support for the construction of community gardens, while 17.5% held the opposite view. Respondents who were female, elderly, and had minors in the household had a higher percentage of supportive statements. Living in different communities, education levels, and monthly income had no significant impact on the results. Community evaluation and horticultural experience had a significant impact on the results. Finally, we discuss the main reasons for willingness. In addition, we found that not all supporters were willing to spend money or time on community gardens. The results of this study are significant for community management decision-making and spatial planning.

Community built environment and the associated ischemic heart disease risk: Evidence from multi-source data in Wuhan, China

IntroductionTheories of epidemiological transition remind the emerging challenge of major non-communicable diseases, among which ischemic heart disease (IHD) has been one of the primary global public health issues. However, the influences of built environment (BE) factors on IHD risk have not been fully investigated. Therefore, there is a need to validate the association between community BEs and IHD risk. MethodMulti-source data aggregated in 1025 communities in Wuhan, China, were adopted to explore the related BE-health nexus. A rich variety of BE factors on the community level, including community attributes, urban form and configuration, facilities, landscape, and location, were systematically employed for modeling with the advanced Bayesian conditional autoregressive model. ResultThe influences of a series of community BEs on IHD risk were identified. Among them, proportion of seniors, FAR, and distance to public transportation, presented positive association with IHD risk, whereas communities with open space ratio, greenness, healthy food accessibility, and sport facilities, presented lower IHD risk. ConclusionBy combining advanced methods and multi-source data, this study deepened the understanding of the multiplicity of health-related BEs on IHD risk. Based on the findings, the idea of planning as a tool for proactive health intervention was emphasized along with specific planning strategies for optimizing resource allocation and promoting healthy development. This study contributed to the existing literature by not only validating important factors but also enriching classic theories and global experience.

Screening Intention Prediction of Colorectal Cancer among Urban Chinese Based on the Protection Motivation Theory

Colorectal cancer poses a serious threat worldwide. Although early screening has been proved to be the most effective way to prevent and control colorectal cancer, the current situation of colorectal cancer screening remains not optimistic. The aim of this article is to apply the protection motivation theory (PMT) to examine the influencing factors on screening intention of colorectal cancer (CRC). This cross-sectional survey was launched in five communities in Wuhan, China. All the eligible urban Chinese were recruited and interviewed using paper-and-pencil questionnaires. The intention of colorectal cancer screening (CRCS) was measured using six PMT subconstructs, including perceived risk, perceived severity, fear arousal, response efficacy, response cost, and self-efficacy. Data on sociodemographic variables and knowledge of CRC were also collected. The structural equation modeling (SEM) method was used for data analysis. Among all the 569 respondents, 83.66% expressed willingness to participate in CRCS. Data of the research fit the proposed SEM model well (Chi-square/df = 2.04, GFI = 0.93, AGFI = 0.91, CFI = 0.91, IFI = 0.91, RMSEA = 0.04). Two subconstructs of PMT (response efficacy and self-efficacy) and CRC knowledge were directly and positively associated with screening intention. Age, social status, medical history, physical activity, and CRC knowledge were indirectly related to the screening intention through at least one of the two PMT subconstructs (response efficacy and self-efficacy). The findings of this study suggest the significance of enhancing response efficacy and self-efficacy in motivating urban Chinese adults to participate in CRC screening. Knowledge of CRC is significantly associated with screening intention. This study can provide useful information for the formulation and improvement of colorectal cancer screening strategies and plans.