Brazilian Community Research Articles

Zaíta não será esquecida: a vida em fragmentos e as crianças em Conceição Evaristo

This study seeks to reflect on violence in impoverished Brazilian communities with a strong criminal presence, as portrayed by contemporary Brazilian author Conceição Evaristo, based on the analysis of the short story «Zaíta forgot to put the toys away» (2014). Considering the extreme form of aggression against children, such as the use of physical or psychological force to impose a will and control, this goes through a conditioning that is manifested by processes of authoritarianism, repression, segregation and social exclusion. The short story analyzes the consequences of a way of thinking, acting and placing oneself in relation to the other marked by direct and indirect experiences of violence that are replicated in a vicious circle and that result in lives that are like the mutilated and lost toy of the little girl Zaíta.

Racism, Death, and Protests in Brazil: digital and traditional news coverage of Black Awareness Day after a racism crime on Twitter

Abstract Purpose On November 19, 2020, a man was brutally murdered by security guards of a supermarket chain located in a city in the very south of Brazil, home to the world’s largest Afro-Black community outside Africa. This killing triggered protests across the country, as a Black man was killed one day before Black Awareness Day. This large popular mobilization happened at the end of 2020 and resembled the George Floyd protests. Despite the anger resonating across communities in Brazil and abroad, the news media coverage on social media resulted in an inequitable distribution of editorial space to both the affective and critical dimensions. As users often adopt view-based practices by not clicking on social media content shared through URLs, it is essential to understand how news media portrays content in short text posted online. Study design Under the lens of news frame and social media theories, our study was built on a multi-method approach combining computational, quantitative, qualitative methods to understand how news media portrays content in a tweet. To do so, we collected 267,576 tweets. They were filtered through the case’s perspective and analyzed using frame theory. Findings Results show that Brazilian news media value different angles concerning Mr. Freitas’s death and subsequent events. While traditional media tends to be more neutral in portraying protests and the killing, digital media raised the debate on the issue and about racism in the country, highlighting protests and using supporting hashtags. Furthermore, cultural hybridity can be seen in Brazil with Black Lives Matter (BLM) movement. Practical and social implications In a media system that shares some aspects with those found in the United States, such as highly commercial media, our study demonstrates the importance of digital media for articulating racial issues and segregation in Brazil. Originality/value A long tradition of scholarship in sociology and communication studies has investigated how news media frames social movements and the impact this coverage might have on protesters and their ability to gather public support in Western-rich democracies. Less well documented is the use of news frames in Brazil. Furthermore, it shows how BLM is hybridized with local topics and has gained traction with digital media outlets. This study aims to fill this gap by becoming the first study investigating how news media frames social movements against racism in Brazil.

Violence in Quilombola women living in rural communities in Brazil.

To estimate the prevalence of psychological, physical, and sexual violence perpetrated against women by their intimate partner (IP) in Quilombola communities located in Espírito Santo State, Brazil. The data is from a population-based cross-sectional study of Quilombola women conducted from 2017 to 2018. In-person interviews collected information on women's sociodemographic characteristics, behaviors, and their experience of violence perpetrated by their IP. The analysis used chi-square test and hierarchical logistic regression. 219 women (94.8% of the invited ones) agreed to participate in the study. 59.0% (95%CI: 5.25-65.5) reported psychological violence; 41% (95%CI: 34.5-47.5) physical violence; and 8.2% (95%CI: 4.6-11.8) sexual violence. Psychological violence was associated with having three or more sexual partners in life, when compared to those who had up to two partners (p = 0,009), and previous violence involving other people outside of family increased the chance of suffering psychological violence by an IP more than nine times (p ≤ 0.001). Regarding physical violence, the association with use of barrier contraception (p = 0.031) and having a partner with other sexual partners (p = 0.024) were protective factors for IP violence. Having 3 or more sexual partners in the last 12 months (p = 0.006), partner using illicit drugs (p = 0,006), and alcoholism in the family (p = 0,001), increased the chance of suffer physical violence by the partner. Sexual violence perpetrated by the IP was associated with miscarriage (p = 0.016), partner using drugs (p = 0.020), and gynecological symptoms (p = 0.045). These results showed the high frequency of intimate partner violence in Quilombola women and highlight the importance of reducing social and race inequities for interrupting the culture of violence against women.

What is the Value of My Catch? Evaluating Fishery Productivity and Socioeconomic Characteristics of a Traditional Urban Fishing Community in Brazil

What is the Value of My Catch? Evaluating Fishery Productivity and Socioeconomic Characteristics of a Traditional Urban Fishing Community in Brazil

Cardiovascular risk factors across different levels of urbanization in Brazilian Afro-derived communities (quilombos).

The frequency of cardiovascular diseases has increased throughout the world. People of African descent have been disproportionately affected, particularly if they reside in urban settings. In this work, we evaluate risk factors associated with cardiovascular diseases (CVD) and other chronic diseases in rural and urban Afro-derived communities (quilombo) in Central Brazil. We also determine if there are associations between the frequency of CVD risk factors, sex, and proximity to urban environments. Through a cross-sectional study of participants (n=347) within three Brazilian Afro-derived communities: Kalunga (a semi-isolated rural community; n=214), Cocalinho (a non-isolated rural village; n=70), and Pé do Morro (an urban community; n=63), we collected data regarding chronic disease (i.e., CVD, diabetes, and hypertension) risk through questionnaires, anthropometrics, blood pressure, and blood samples using standard protocols. Differences between variables were tested by the Chi-square test of Pearson and Fisher's Exact Test, independent sample t-tests, analysis of variances, and Kruskal-Wallis tests (p ≤ .05). The prevalence of hypertension, overweight, obesity, and other cardiovascular risk factors were higher in the non-isolated rural and urban communities than in the semi-isolated rural community. We found significant sex differences in the distribution of the CVD risk factors, with all occurring at a higher frequency among females. Our findings indicate that Brazilian Afro-derived communities are currently going through an epidemiological transition. The urban lifestyle and its environmental factors are likely contributing to an escalation in cardio-metabolic disease risk. However, the magnitude of this transition differentially impacts the sexes, as females suffer a higher frequency of risk factors compared to males.

The effects of an invasive soft coral on the structure of native benthic communities

Species invasion is a major threat to marine biodiversity and function; thus, studying the effects of recently reported exotic species is extremely important. Several soft coral species (Alcyonacea) have invaded the Atlantic Ocean but their effects are poorly known. Here, we investigated the effects of the invasive species Sarcothelia sp. (Alcyonacea, Xeniidae) on native benthic shallow reef communities in Brazil. We hypothesized that increasing Sarcothelia sp. abundance would be related to species richness decreases and native community structure changes. Multivariate analysis showed significant dissimilarity between invaded (high Sarcothelia sp. abundance) and non-invaded areas (high abundance of the octocoral Neospongodes atlantica and zoantharians). The invaded area showed less species composition variability (i.e., homogenization) than non-invaded ones. Within the invaded area we observed that Sarcothelia sp. abundance reduced species richness. The lowest native benthic richness (10 taxa) was observed in a transect with the highest invader cover, while the transect with the lowest Sarcothelia sp. cover presented 26 native taxa. These findings are likely related to the invasive novel functional traits, i.e., invader growth form and allelochemicals. A clear inverse abundance pattern between invasive Sarcothelia sp. and N. atlantica, indicated an intense competition between octocorals. Our study showed remarkable evidence of negative impacts of invasive soft corals on reef biodiversity. There is an urgent need for experiments evaluating changes in different ecological processes and to implement management actions.

Women in Conflict and Post-conflict Situations: An Anthology of Cases from Iraq, Iran, Syria, and Other Countries

Women in Conflict and Post-conflict Situations: An Anthology of Cases from Iraq, Iran, Syria, and Other Countries

Fala aí checklist: Peer conversations recognising practices of care, hope and solidarity in times of loss and difficulty

In Brazil, as elsewhere, The COVID-19 pandemic and related upheavals exacerbated problems like unemployment and domestic violence. Feelings of hopelessness, isolation and impotence became pervasive. Seeking ways to respond to the uncertainty, insecurity and discouragement that many young people were expressing, the author sought ways that stories of courage, care, hope and solidarity could be shared and acknowledged. Drawing on the ‘checklist of psychological and social resistance’ developed in Lebanon by David Denborough and Mohamad Safa, a conversation guide for Brazilian communities was developed. It can be used by professionals, but is particularly designed for use among friends, family members and colleagues. It can even be used for individual reflection. Through consultation with the Nelson Mandela Favela in Rio de Janeiro, and its young people in particular, the Fala aí checklist was refined to be accessible and culturally resonant as a prompt for peer conversations that sustain hope and connection. The Fala aí checklist is included in the paper.

Serum 25 hydroxyvitamin D concentrations in individuals over 80 years old and their correlations with musculoskeletal and health parameters.

The present study aims to evaluate the serum concentrations of 25 hydroxyvitamin D[25(OH)D] in individuals aged ≥80 years, independent, free-living in Sao Paulo, Brazil (Lat 23.5 oS), and to investigate their associations with musculoskeletal system, physical performance and health markers. This cross-sectional study included 212 community dwellers aged ≥80 years and evaluated serum 25(OH)D, PTH, calcium, albumin, phosphorus, creatinine, bone markers, and bone mineral density. Physical performance was evaluated with stationary march, Flamingo, and functional reach tests, questionnaires to assess falls and fractures in the previous year, energy expenditure (MET), and Charlson index. Physical activity was evaluated with the International Physical Activity Questionnaire. Vitamin D deficiency (<20 ng/mL) was observed in 56% and severe vitamin D deficiency (<10 ng/mL) in 13% of those individuals. Serum concentrations of 25(OH)D were significantly and positively associated with BMD total hip (p = 0.001), femoral neck (p = 0.011) and 33% radius (p = 0.046) BMDs, MET (p = 0.03) and functional reach test (p = 0.037) and negatively with age (p = 0.021), PTH (p = 0.004) and osteoporosis diagnosis (p = 0.012). Long-lived individuals with 25(OH)D ≥ 20 ng/mL had higher total hip and femoral neck BMDs (p = 0.012 and p = 0.014, respectively) and lower PTH (p = 0.030). In multiple linear regression analysis, age and osteoporosis diagnosis remained negatively associated with 25(OH)D levels (p = 0.021 and p = 0.001, respectively), while corrected calcium and cholecalciferol use remained positively associated (p = 0.001 and p = 0.024, respectively). We observed high vitamin D inadequacy prevalence in those Brazilian community dwellers' oldest old. Serum concentrations of 25(OH)D were positively associated with bone mass and dynamic balance, and negatively with PTH and osteoporosis diagnosis. Additionally, 25(OH)D ≥ 20 ng/mL was associated with better bone mass and lower PTH levels.

HTLV infection in Brazil’s second-largest indigenous reserve

Human T-lymphotropic viruses 1 and 2 (HTLV-1/2) have a worldwide distribution. HTLV-1 has been associated with several diseases, including an aggressive malignant disease known as adult T-cell leukemia/lymphoma and a chronic inflammatory neurological disease called HTLV-1-associated myelopathy, while HTLV-2 has not been definitively associated with diseases. HTLV-2 is most prevalent in specific groups such as injecting drug users and the indigenous population. In Brazil, most studies about HTLV in indigenous are carried out in indigenous communities from the north of the country. Mato Grosso do Sul (MS), Central Brazil, has the second-largest indigenous population in Brazil. However, there is no available data about HTLV infection in this group. We conducted the first investigation of HTLV-1/2 infection prevalence in the indigenous population from Jaguapiru and Bororó villages in Dourados City, MS, to provide the prevalence and molecular characterization of HTLV. For that, a total of 1875 indigenous participated in the study. All the serum samples were screened by an enzyme-linked immunosorbent assay commercial kit for the presence of anti-HTLV-1/2 antibodies. Positive samples were confirmed by HTLV-1/2 Western Blot assay. The HTLV-1 5’LTR region was detected by nested PCR amplification and sequenced by Sanger. Most of the study population declared belonging to Guarani-Kaiowá ethnicity (69.18%), 872 (46.51%), and 1003 (53.49%) were from Jaguapiru and Bororó villages, respectively. The median age of participants was 31 years, and 74.24% were females. Two individuals were detected with HTLV-1 (0.1%; CI 95% 0.1–0.2). The phylogenetic analysis revealed that isolates belong to the Cosmopolitan subtype and the Transcontinental subgroup (HTLV-1aA). The low HTLV-1 prevalence found in this study is similar to that observed among blood donors, and pregnant populations from Mato Grosso do Sul. The absence of HTLV-2 infection among these Brazilian indigenous communities would suggest a distinct behavior pattern from other indigenous populations in Brazil.

International Journal of Role-playing 12 -- Full Issue -- IJRP

IJRP 12: Full Issue&#x0D; Table of Contents&#x0D; William J. White, Evan Torner, and Sarah Lynne Bowman,“Editorial: The Social Epistemology of Analog Role-Playing Game Studies”&#x0D; Reflections on the interdisciplinary and heterogeneous nature of role-playing games studies, as evident in the five uniquely distinct articles in Issue 12.&#x0D; Tadeu Rodrigues Iuama and Luiz Falcão, “Analog Role-Playing Game Studies: A Brazilian Overview”&#x0D; An overview of the history of role-playing games and their respective game communities in Brazil, as well as the development of role-playing game study scholarship, including research on RPGs in education.&#x0D; Marissa Baker, “An Analysis of the Literature Surrounding the Intersection of Role-Playing Games, Race, and Identity”&#x0D; A review and examination of a body of multidisciplinary scholarship on representation and race in fantasy RPGs such as Dungeons &amp; Dragons and World of Warcraft.&#x0D; Pascal Martinolli, “A Scholarly Character Sheet to Frame Learning Activities and Improve Engagement”&#x0D; An evaluation of the use of role-playing game inspired character sheets in a graduate seminar on library instruction to assess the participants’ knowledge, present the curriculum, and measure the their progress.&#x0D; Hanne Grasmo and Jaakko Stenros, “Nordic Erotic Larp: Designing for Sexual Playfulness”&#x0D; Mapping, organizing, and understanding the phenomena of erotic larp design through a systemic examination of 25 design abstracts of Nordic art larps from the last decade.&#x0D; Christian Mehrstam, “Recomposing Lovecraft: Genre Emulation asAutopoiesis in the First Edition of Call of Cthulhu”&#x0D; An examination of how genre is emulated in the first edition of Call of Cthulhu (1981), analyzing the game’s potential to answer social needs during the Reagan era.

Patient misadventures caused by prescription errors detected at a brazilian community pharmacy

Background: Efforts to reduce medication errors in healthcare have been widespread around the world with the aim to improve the quality of care. Failures observed at the prescription phase are reported as being the most prevalent preventable errors. Adverse events related to inappropriate prescriptions are an important threat to patient safety. In this context, a community pharmacist is in a strategic position to evaluate, detect, and correct faults that may have occurred during prescribing. Consequently, this reduces the risk of negative clinical and economic outcomes. Objective: To identify the consequences of prescription errors that impede drug dispensing at a Brazilian community pharmacy for the perspective of patients. Method: We conducted a cohort study, with no comparison group, in a Brazilian community pharmacy, which included patients with prescription errors which made it impossible for correct drug dispensing. Patients were interviewed at the time of problem detection and followed up until an outcome was reached. Results: Of the 32 interviewed patients, 23 (71.9%) reported some damage to their health due to a delay in starting treatment, and 19 (59.4%) experienced extra expenses due to medication not being dispensed. Conclusion: Prescription errors that preclude the dispensing of any medication can lead to negative clinical outcomes and a financial loss to patients.

19.2 Hoasca Use in Adolescents in a Brazilian Religious Community

In 2001, a follow-up to a biomedical-psychiatric 1993 study of adult members of the syncretic church, Uniao do Vegetal (UDV), was conducted in Brazil to examine the effects of legally administered ayahuasca to adolescent members of the church. The goal of the study was to determine if a sample of adolescents with histories of ayahuasca use in a religious setting had sustained negative psychological outcomes from their participation in UDV ceremonies and to clarify the risk-to-benefit ratio of ayahuasca when consumed within the UDV ceremonial context.

FACTORS ASSOCIATED WITH MENTAL SUFFERING IN PEOPLE WITH DIABETES MELLITUS DURING THE COVID-19 PANDEMIC

Objective: to analyze the factors associated with mental distress in people with diabetes mellitus during the COVID-19 pandemic. Method: cross-sectional study, conducted in two Brazilian virtual communities of the Facebook platform, in the period from August 2020 to January 2021. The sample totaled 111 people with diabetes. The evaluation of health conditions was performed using an electronic form, and the Self Report Questionnaire-20 was used to identify mental suffering. Descriptive and inferential analyses were expressed by frequencies and simple and multiple logistic regression. Results: mental suffering is associated with being female, having a previous history of mental disorders (depression and anxiety), having been diagnosed with diabetes for more than six years, and the presence of ophthalmologic complications, which increase the chances of emotional instability. Conclusion: the study offers subsidies to the direction of support strategies that minimize the psychosocial impacts of the pandemic on people with diabetes.

The Ecological Footprint of Happiness: A Case Study of a Low-Income Community in the City of São Paulo, Brazil

An ecological footprint is an accounting tool that reports the balance between resource supply and demand to assess environmental sustainability. Among the many available indicators of social progress, happiness reflects how a person feels about their quality of life. We combined these two approaches to assess the ecological efficiency of social performance in the low-income community of Felicidade, in São Paulo, Brazil, in 2019. We assessed the ecological footprint and gross domestic happiness (GDH) through questionnaires. We found that the community has a lower environmental footprint than higher-income communities in Brazil. However, the per capita ecological footprint in the community is still above what is available per person globally. We found that the community has a high level of life satisfaction (GDH = 0.86) and that the main contributor to happiness is health, time use, psychological wellbeing, education, good governance, and community vitality. The results suggest that other contributors unrelated to income are more robust determinants of happiness. In Brazil, despite higher footprints characterizing higher-income communities, further efforts in low-income communities are needed to reduce environmental footprints, ensure dignified income, and nurture the underlying conditions for high levels of happiness and social capital.

Dynapenia in all-cause mortality and its relationship with sedentary behavior in community-dwelling older adults

The aim of the present study was to investigate the relationship of dynapenia combined with sedentary behavior (SB) on the risk of mortality in older adults living in a Brazilian community. A total of 322 participants aged ≥ 60 years from the ELSIA (Longitudinal Study of Elderly Health in Alcobaça) prospective cohort were included. Dynapenia was diagnosed when the handgrip strength was < 27 ​kg for men and < 16 ​kg for women. The exposure time to SB was assessed considering the total time spent sitting during one day in the week and one day on the weekend. When combined with dynapenia, we derived the construction of four groups: best behavior (absence of dynapenia and low SB), intermediate behavior (absence of dynapenia and high SB; presence of dynapenia and low SB) and worst behavior (presence of dynapenia and high SB). Mortality was assessed by the follow-up time until death and/or censorship. During the 5-year follow-up of the study, 55 participants progressed to death. In the adjusted models, the dynapenia and the time spent exposed to SB were analyzed in a combined way, the older adults with worse behavior (high SB and dynapenia) had higher risk ratios for mortality (hazard ratio 2.46; 95% confidence interval 1.01–5.97) than the best behavior group. Older adults with dynapenia are at greater risk for all-cause mortality, which is aggravated by the addition of longer exposure to SB.

Human sporotrichosis: recommendations from the Brazilian Society of Dermatology for the clinical, diagnostic and therapeutic management

BackgroundThe increase in the zoonotic epidemic of sporotrichosis caused by Sporothrix brasiliensis, which started in the late 1990s in Rio de Janeiro and is now found in almost all Brazilian states, has been equally advancing in neighboring countries of Brazil. Changes in the clinical-epidemiological profile, advances in the laboratory diagnosis of the disease, and therapeutic difficulties have been observed throughout these almost 25 years of the epidemic, although there is no national consensus. The last international guideline dates from 2007. ObjectivesUpdate the clinical classification, diagnostic methods and recommendations on the therapeutic management of patients with sporotrichosis. MethodsTwelve experts in human sporotrichosis were selected from different Brazilian regions, and divided into three work groups: clinical, diagnosis and treatment. The bibliographic research was carried out on the EBSCOHost platform. Meetings took place via electronic mail and remote/face-to-face and hybrid settings, resulting in a questionnaire which pointed out 13 divergences, resolved based on the opinion of the majority of the participants. ResultsThe clinical classification and laboratory diagnosis were updated. Therapeutic recommendations were made for the different clinical forms. ConclusionPublication of the first national recommendation, carried out by the Brazilian Society of Dermatology, aimed at the Brazilian scientific community, especially dermatologists, infectologists, pediatricians, family medicine personnel, and laboratory professionals who work in the management of human sporotrichosis.

A Geographic Analysis of the Interdisciplinary Collaborations in the Brazilian Scientific Community

Interdisciplinary collaborations have recently attracted the attention of scholars, since they help bridging academic relationships and contribute to make scientific collaboration networks even stronger. However, previous works on this subject have mainly focused on characterizing such interdisciplinary collaborations in specific research groups or scientific communities. In this article, we start from a previous work in which we characterized the interdisciplinary collaborations within the entire Brazilian scientific community, as defined according to the upper level of the knowledge area classification scheme proposed by CNPq, the Brazilian National Council for Scientific and Technological Development, considering the following eight major areas: Agrarian Sciences, Applied and Social Sciences, Biological Sciences, Engineering, Exact and Earth Sciences, Health Sciences, Humanities, and Linguistics, Letters and Arts. Based on this interdisciplinary collaboration network, we conducted a geographic analysis that characterizes how these collaborations have been spread across the Brazilian geographic regions. Overall, our results show strong collaborative ties involving the triad formed by the three main Brazilian geographic regions (Southeast, South and Northeast) for all major areas. Besides, three of the eight major areas (Agrarian Sciences, Biological Sciences, and Health Sciences) show a massive participation in interdisciplinary collaborations across all regions. Despite that, geographic proximity is an important factor, since the proportion of interdisciplinary collaborations involving researchers from the same region is high. Finally, we analyze the patterns of interdisciplinary collaboration by regions and by major areas, thus showing that the Brazilian interdisciplinary network is highly connected.

Psychometric study of the brazilian version of the personality inventory for DSM-5-paper-and-pencil version.

The Personality Inventory for DSM-5 - Self Reported Form (PID-5-SRF) operationalizes Criterion B of the personality alternative model of DSM-5 Section III and has already been cross-culturally adapted to many countries. The objective is to present evidence of validity and reliability of the Brazilian version of PID-5 (pencil-and-paper) in a Brazilian community sample. The sample was composed of 730 individuals from the general population [67.8% women, aged 33.84 (SD = ±15.2), 69.5% ≥ 12 years of schooling]. The participants were recruited in academic, organizational, healthcare, and business facilities in three Brazilian states. The snowball method was used. The PID-5 Brazilian version and the Revised NEO-Five Factor Inventory (NEO-FFI-R) were individually applied, and the retest was applied 30 days after. Satisfactory internal consistency (facets α ≥0.51; domains α ≥0.82) and test-retest reliability (facets ICC ≥ 0.45; domains ICC ≥0.76) were found, but a floor effect was verified in 97.7% of the items. Regarding convergent validity, strong correlations were found between the PID-5 and the NEO-FFI-R domains (r = −0.44 to 0.70). Ten facets did not fit the unidemensional structure. Confirmatory Factor Analyses did not present adequate goodness of fit, and Exploratory Analyses indicated that a five-factor model is more appropriate, though it presents some peculiarities concerning the original model. PID-5 also presented satisfactory goodness of fit to the personality hierarchical model. Generally, the instrument's psychometric indicators favor its use in the Brazilian context. However, some aspects demand attention, and more specific studies should be conducted to verify the impact of reverse-scored items, floor effect, and peculiarities of its internal structure (some facets' multidimensionality and interstitiality) concerning the original model.

Essential oil from the leaves of Eugenia pohliana DC. (Myrtaceae) alleviate nociception and acute inflammation in mice.

Eugenia pohliana DC.(Myrtaceae) is used in folk medicine by communities in Brazil. However, there are no reports on its biological activity. This is the first study to identify the components of E. pohliana essential oil (EpEO) and evaluate their antinociceptive and anti-inflammatory activities in an in vivo model at doses of 25, 50, and 100mg/kg. The essential oil (EO) was obtained by hydrodistillation, and the analysis was performed by gas chromatography coupled with mass spectrometry. Antinociceptive activity was evaluated by writhing tests, tail movement, and formalin (neurogenic and inflammatory pain); naloxone was used to determine the nociception mechanism. Anti-inflammatory activity was assessed by oedema and peritonitis tests. We found that (E)-β-caryophyllene (BCP) (15.56%), δ-cadinene (11.24%) and α-cadinol (10.89%) were the major components. In the writhing test, there was a decrease in writing by 42.95-70.70%, in the tail movement, an increase in latency time by 69.12-86.63%, and in the formalin test, there was a reduction in pain neurogenic by 29.54-61.74%, and inflammatory pain by 37.42-64.87%. The antinociceptive effect of EpEO occurs through the activation of opioid receptors. In addition, a reduction in inflammation by 74.93‒81.41% was observed in the paw edema test and inhibition of the influx of leukocytes by 51.86‒70.38% and neutrophils by 37.74‒54.72% in the peritonitis test. It was concluded that EpEO has antinociceptive effect by the opioid pathway, as shown by the inhibitory effect of naloxone, and anti-inflammatory actions, and that its use does not cause hemolytic damage or behavioral change.