With the maturity of the Internet of Things technology, medical institutions have established a positioning and sensing wireless IoT platform for the entire medical institution by using technologies such as Bluetooth positioning beacons, LoRa communication base stations, positioning and map engines. The intelligent medical waste collection and transfer vehicle integrates the wireless Internet of Things platform in the hospital based on 4G/5G modules, Bluetooth positioning terminals, electronic weighing and other technologies. An information-based, intelligent, and visualized "smart medical waste" management system covering all aspects of medical waste generation, collection, temporary storage, transfer, and disposal has been established in medical institutions. This set of solutions can greatly reduce the number of communication base stations deployed in hospital indoor buildings, the number of weak current construction and access switches in hospitals, save a lot of unnecessary costs for weak current construction and access switches and meet the real-time needs of intelligent medical waste collection and transfer vehicles such as real-time positioning, real-time tracking, video linkage, trajectory playback, and transfer route deviation alarms, which have certain reference significance in the practice of intelligent medical waste construction technology in hospitals based on smart IoT. The article describes one case of implementation of the technology in a university Hospital.