Common Source Of Information Research Articles

Gender confirmation hormonal treatment use in young Polish transgender binary and non-binary persons.

Gender confirmation hormonal treatment (GCHT) is a cornerstone of medical treatments for persistent gender dysphoria, which is expected and required by many transgender binary and non-binary individuals. Many protocols have been published, and the qualification process is guided by the World Professional Association for Transgender Health Standards of Care. The standards and other documents such as the Endocrine Society Clinical Practice Guideline provide gender confirmation hormonal care also for minors. However, the issue of starting these treatments in younger populations is still marked by controversy. This preliminary study aimed to inquire into GCHT (medications used, timing of its initiation, its tolerance, and sources of information on the treatment) in a convenience sample of young Polish transgender binary and non-binary persons. A total of 166 adult transgender participants answered our online questionnaire between November 2020 and December 2021. The population was divided into 2 groups: assigned male at birth (AMB, n = 37) and assigned female at birth (AFB, n = 126). Subsequently, division into binary and non-binary was applied to these groups. Most patients (91.9% AMB and 92.2% AFB) did not use gender confirmation medical treatments before the age of 18 years. The most common medication used for GCHT before the age of 18 was cyproterone acetate for AMB and testosterone for AFB. When asked about their opinion on the timing (age) of initiating GCHT, 73.1% of the AMB and 59.2% of the AFB participants shared the view that it had been initiated much too late. By far the most common source of information on GCHT and gender confirmation surgery (GCS) was the Internet (92.2%). These treatments (including pubertal blocking) seem to be rarely commenced in Poland before the age of 18 years. In adults, treatment consists mostly of either testosterone or oestradiol, and cyproterone acetate and, more seldom, spironolactone are used as antiandrogens in persons assigned male at birth. In turn, gonadotropin-releasing hormone agonists are barely used at all. Specialists need to be more aware that withholding treatment in minors with gender dysphoria is not a health-neutral option. Gonadotropin-releasing hormone agonists should also be more often considered as an alternative to cyproterone acetate in the context of long-term safety.

COVID-19 Times and Dental Students: Challenges and Adapting with New Normal

Abstract Background Dental students were adversely impacted by coronavirus disease-2019 (COVID-19) leading to changes in their personal and professional lives. They have been under stress and adapting to new technologies and scenarios at the workplace. With the omicron threat looming, new challenges await them. The study aims to assess perceptions, stress, and coping mechanisms adopted by dental students during COVID-19 times, and to invite suggestions to improve the professional scenario. Methodology A cross-sectional self-administered questionnaire-based study was planned for third- and final-year undergraduate and postgraduate dental students from dental colleges around the Chandigarh region. Convenient sampling was done. Thirty-item questionnaire was sent via email and WhatsApp groups in the form of Google Form. p-Value less than 0.05 was taken as statistically significant. Results Overall, 389 students participated, with majority (93.8%) being 21 to 25 years of age, females (75.6%), and undergraduates (90.2%). Also, 35% had a positive COVID-19 family history. Social media was the most common source (81.1%) of information regarding the pandemic. The majority received online teaching (84.83%) and gave online exams (58.6%). Altered sleep patterns (81.5%) and increased screen time (82%) were reported. Being female (stress score 11.15; p < 0.001; Mann–Whitney U test), final-year undergraduate (stress score 11.1; p < 0.017; Kruskal–Wallis test), and positive COVID-19 family history (stress score 11.83; p < 0.002; Mann–Whitney U Test) was associated with significantly higher mean stress scores. Watching movies (30%) and sharing a stressful feeling with family (47%) were the most common coping mechanisms. Students suggested flexible work schedules, more offline work with better safety protocol, and counselors for the future. Conclusion Decreasing number of stressors and increasing involvement in the coping mechanism will help students to better embrace the impact of the COVID-19 pandemic.

Social Media as a Source of Knowledge about Gene Therapy for Spinal Muscular Atrophy.

Social media is one of the most common sources of medical information. We aimed to evaluate the information contained on websites, including social media and descriptions of fundraisers, in terms of the reliability of knowledge about SMA and gene therapy with onasemnogen abeparvovec. We used a set of available online links found using the Newspointtool. Initially, 1525 texts were included in the study, and after applying the inclusion and exclusion criteria, 112 texts were qualified for analysis using the DISCERN scale and the set of questions prepared by the authors. We observed that most of the texts had poor (48.65%) and medium (27.03%) reliability in the final reliability assessment. All the texts selected for the study were related to gene therapy, although few contained key information about it. In addition, the authors of the entries used various words and phrases that influenced the readers' perceptions of the text. Of the analyzed sources, 68.8% had an emotional component. Social media is a poor source of information about gene therapy for SMA in Poland. The analyzed texts do not provide a full and complete description of the SMA problem. However, it is important to remember that the Internet is a changing source of information and will hopefully contain more relevant entries in the future.

A study of rural domestic helpers knowledge, attitude, and practice of COVID-19 in Mizoram, India

Background: In times of an epidemic such as coronavirus disease 2019 (COVID-19), the public’s knowledge and attitude toward the disease affects the ability to abide to different preventive measures. Aims and Objectives: (1) to assess the knowledge and awareness of the domestic helpers in a tribal population, (2) whether the domestic helpers practice appropriate preventative measures that are recommended by WHO. Materials and Methods: This cross-sectional study was designed and carried out using questionnaire among rural domestic workers in Mizoram, above 14 years of age belonging to both Mizo and Non-Mizo ethnicity. Data were collected from 105 participants and analyzed through t-test, one-way analysis of variance and Pearson correlation analysis. Results: Majority of the respondents had higher secondary level of education (78.1%) and 95.2% could identify COVID-19 as a communicable disease. Almost all the participants (97.1%) were afraid of infection and the majority (92.4%) had fear of dying with the disease. Three-fourth of the participants were working during the pandemic of which 44.8% had volunteered. Media (68.6%) was the most common source of information about the disease. The education level was significantly associated with knowledge and attitude scores whereas there were no significant differences with respect to the practice (P>0.05). Conclusion: Our findings indicate an overall good KAP of the rural domestic workers. Since these workers move from house to house and also take care of the vulnerable, and that they themselves and the families, they work for may be at an increased risk of infection with COVID-19, these findings are important from a health campaign perspective.

Liver Transplant Recipients Speak Out on Public Awareness and Education Surrounding Alcohol-Related Health Effects: A Survey Study.

Compared to other recreational substances in Canada, alcohol consumption incurs the highest healthcare costs. Liver transplant recipients are unique stakeholders as members of the general public with lived experiences of liver disease. We sought to explore their perspectives on the current state of public education on alcohol-related health effects. The most recent 400 liver transplant recipients at Vancouver General Hospital, Canada, were invited to participate in an anonymous online survey on alcohol-related health effects by mail, email, and phone. Of 372 contacted patients, 212 (57%) completed the survey. Most patients were between 60-79 years, 63% were male, and 69% were Caucasian. The most common liver conditions leading to transplant were viral hepatitis (33%), alcohol-related liver disease (16%), autoimmune liver disease (14%), and non-alcoholic fatty liver disease (15%). Most patients knew that alcohol leads to liver failure (85%), but fewer knew about alcohol leading to cancer (54%), heart disease (50%), and damage to other organs (58%). Most common sources of information included public media (61%), family and friends (52%), and physicians (49%), with narrative comments about learning of alcohol-related health effects after liver diagnosis. Most patients believed that public health education at a middle/high school level would have long-term efficacy (72%) compared to health warning labels (33%) and safety messaging in commercials (39%). Current public education was felt to be adequate by only 20% of patients and 73% of patients supported health warning labels. Liver transplant patients reported a high, but not universal, awareness of alcohol-related health effects. A majority thought that current public health efforts were inadequate; it is critical to implement public health interventions to ensure consumers are able to make an informed decision on alcohol consumption.

Assessment of knowledge, perception, and practice patterns of Jordanian optometrists during COVID-19 pandemic: a cross-sectional online survey

To investigate knowledge, risk perception, and attitude towards corona virus disease 2019 (COVID-19) and infection control measures among optometrists in Jordan. A cross-sectional survey was distributed through social media platforms to optometrists registered with the Jordanian syndicate and Jordanian association of optics. Information on participants' socio-demographic characteristics, knowledge of clinical features of COVID-19, risk assessment and infection control measures for preventing disease transmission were collected. A total of 135 optometrists (80 females and 55 males) with a mean age of 32±10y responded to the survey. Most optometrists were aware of COVID-19 symptoms, modes of transmission and measures for preventing COVID-19 and transmission in the ophthalmic setup. However, more than half of the optometrists did not receive any training about protection or infection control by their employers at their work place. Social media was the most common source of information on COVID-19 (76%). Most optometrists (85.2%) thought that the virus could be detected in tears, and 45.9% thought that red eye is a symptom of COVID-19. Optometrists in Jordan are aware of the clinical features and preventive measures related to COVID-19 infection. However, training on infection control is lacking and needs to be improved. Guidelines by international professional optometric associations should be promoted through regional and national associations to all registered optometrists and access to peer review. Journals should be encouraged to ensure that the knowledge about the pandemic is up to date and accurate.

Cross-sectional estimates of population health from the Survey of Health and Retirement in Europe (SHARE) are biased due to health-related sample attrition

Cross-sectional data from the Survey of Health, Ageing and Retirement in Europe (SHARE) are a common source of information in comparative studies of population health in Europe. In the largest part, these data are based on longitudinal samples, which are subject to health-specific attrition. This implies that estimates of population health based on cross-sectional SHARE datasets are biased as the data are selected on the outcome variable of interest.We examine whether cross-sectional datasets are selected based on health status. We compare estimates of the prevalence of full health, healthy life years at age 50 (HLY), and rankings of 18 European countries by HLY based on the observed, cross-sectional SHARE wave 7 datasets and full samples. The full samples consist of SHARE observed and attrited respondents, whose health trajectories are imputed by microsimulation. Health status is operationalized across the global index of limitations in activities of daily living (GALI). HLY stands for life expectancy free of activity limitations.Cross-sectional datasets are selected based on health status, as health limitations increase the odds of attrition from the panel in older age groups and reduce them in younger ones. In older age groups, the prevalence of full health is higher in the observed cross-sectional data than in the full sample in most countries. In most countries, HLY is overestimated based on the cross-sectional data, and in some countries, the opposite effect is observed. While, due to the small sample sizes of national surveys, the confidence intervals are large, the direction of the effect is persistent across countries. We also observe shifts in the ranking of countries according to HLYs of the observed data versus the HLYs of the full sample.We conclude that estimates on population health based on cross-sectional datasets from longitudinal, attrited SHARE samples are over-optimistic.

Management of acutely injured cattle by on farm emergency slaughter: Survey of veterinarian views.

Fitness to transport is a key provision in animal welfare regulations in the European Union, and for the management of acutely injured cattle. Whilst treatment may be appropriate for some injuries, three common production outcomes for acutely injured cattle are; on farm emergency slaughter (OFES), casualty slaughter (CS) or euthanasia. The aims of this study were to evaluate the perceptions of veterinarians, working in Ireland, on the use of OFES for the management of acutely injured cattle and to evaluate the influence of capacity, willingness and opportunity on their ability to operate OFES. Two online surveys of veterinarians working in Ireland, Private Veterinary Practitioners (PVPs) and Official Veterinarians (OVs), were conducted through QualtricsXM over a 7-week period between April and June of 2021. Quantitative and qualitative questions were developed and analyzed using the tripartite framework of capacity, willingness, and opportunity to collect relevant data about the management of acutely injured cattle and the provision of OFES in Ireland by veterinarians. 43 OVs and 85 PVPs participated in the survey. OVs regulated on average 4.2 abattoirs, of which 21.6% accepted OFES. Participants reported 343 and 377 OFES and CS, respectively, in 2020. 62.4% PVPs had not certified cattle for OFES, or CS. Limb fracture accounted for 79% OFES, 34.5% CS and 47.9% euthanized acutely injured cattle. 63.3% OVs and 44% PVPs were not aware of abattoirs providing OFES within 100 km of their workplace. Lack of availability of OFES negatively associated with PVP knowledge of the procedure. Regulations and guidelines were the most common source of information on OFES for PVPs. Increasing the availability of OFES may help to improve the management of acutely injured cattle, especially those with limb fractures that are unfit for transport.

Health information and COVID-19 vaccination: Beliefs and attitudes among Japanese university students.

Coronavirus disease 2019 (COVID-19) vaccination of adolescent and young adults is important for infection control. Factors influencing vaccination behavior in this age group include the source of information about the vaccine and social norms. However, there are few studies on factors influencing vaccination behavior among Japanese university students. This study aimed to assess beliefs, attitudes, and sources of information about the COVID-19 vaccine among university students in Japan. A cross-sectional online questionnaire survey was conducted among students in Teikyo University, Japan in September, 2021. The survey was designed to collect demographic information, vaccination status, attitudes, beliefs, and anxiety about the vaccine, sources of information, and whether or not the participant watched an educational movie. The factors associated with beliefs and attitudes were analyzed using logistic and linear regression. A total of 4,062 valid questionnaires were retrieved. The positive vaccine behavior group included 3,725 students (91.7%). The most common source of information on the COVID-19 vaccine was TV/radio (75.0%), and the most common Social networking service (SNS) for COVID-19 information was Twitter (31.1%). Approximately 85% students believed in the efficacy of vaccination. Positive attitude was associated with female sex and watching an educational movie by the university. Concern about the vaccine was positively associated with information from acquaintances or Instagram, and negatively associated with information from Twitter, and watching the educational movie. The majority of students had positive beliefs and attitudes toward COVID-19 vaccination, and social media and educational movies produced by the university had a large influence on their attitude toward vaccination behavior. On the contrary, some students were anxious about vaccination. Promotion of educational movies on social media by the universities is an effective way to encourage vaccination among young people.

Radiomics in Head and Neck Cancer Outcome Predictions.

Head and neck cancer has great regional anatomical complexity, as it can develop in different structures, exhibiting diverse tumour manifestations and high intratumoural heterogeneity, which is highly related to resistance to treatment, progression, the appearance of metastases, and tumour recurrences. Radiomics has the potential to address these obstacles by extracting quantitative, measurable, and extractable features from the region of interest in medical images. Medical imaging is a common source of information in clinical practice, presenting a potential alternative to biopsy, as it allows the extraction of a large number of features that, although not visible to the naked eye, may be relevant for tumour characterisation. Taking advantage of machine learning techniques, the set of features extracted when associated with biological parameters can be used for diagnosis, prognosis, and predictive accuracy valuable for clinical decision-making. Therefore, the main goal of this contribution was to determine to what extent the features extracted from Computed Tomography (CT) are related to cancer prognosis, namely Locoregional Recurrences (LRs), the development of Distant Metastases (DMs), and Overall Survival (OS). Through the set of tumour characteristics, predictive models were developed using machine learning techniques. The tumour was described by radiomic features, extracted from images, and by the clinical data of the patient. The performance of the models demonstrated that the most successful algorithm was XGBoost, and the inclusion of the patients' clinical data was an asset for cancer prognosis. Under these conditions, models were created that can reliably predict the LR, DM, and OS status, with the area under the ROC curve (AUC) values equal to 0.74, 0.84, and 0.91, respectively. In summary, the promising results obtained show the potential of radiomics, once the considered cancer prognosis can, in fact, be expressed through CT scans.

Modelling forest volume with small area estimation of forest inventory using GEDI footprints as auxiliary information

• A suitable GEDI RH metric was selected to represent NFI dominant height at plot level. • A method that pairs up NFI plots with nearby GEDI footprints up to a critical distance suggested by the semi-variance examination. • Small area estimation of forest volume was improved with the help of GEDI auxiliary data. The French National Forest Inventory provides detailed forest information up to large national and regional scales. Forest inventory for small areas of interest within a large population is equally important for decision making, such as for local forest planning and management purposes. However, sampling these small areas with sufficient ground plots is often not cost efficient. In response, small area estimation has gained increasing popularity in forest inventory. It consists of a set of techniques that enables predictions of forest attributes of subpopulation with the help of auxiliary information that compensates for the small field samples. Common sources of auxiliary information usually come from remote sensing technology, such as airborne laser scanning and satellite imagery. The newly launched NASA’s Global Ecosystem Dynamics Investigation (GEDI), a full waveform Lidar instrument, provides an unprecedented opportunity of collecting large-scale and dense forest sample plots given its sampling frequency and spatial coverage. However, the geolocation uncertainty associated with GEDI footprints create important challenges for their use for small area estimations. In this study, we designed a process that provides NFI measurements at plot level with GEDI auxiliary information from nearby footprints. We demonstrated that GEDI RH 98 is equivalent to NFI dominant height at plot level. We stressed the importance of pairing NFI plots with nearby GEDI footprints, based on not only the distance in between but also their similarities, i.e., forest heights and forest types. Subsequently, these NFI-GEDI pairs were used for small area estimations following a two-phase sampling scheme. We showcased that, with an adequate sample size, small area estimation with GEDI auxiliary data can improve the accuracy of forest volume estimates.

WHAT ARE PATIENTS SEARCHING ON INTERNET IN RELATION TO URTICARIA? AN INFODEMIOLOGY ANALYSIS

<h3>Introduction</h3> Urticaria is a complex and debilitating disease that impacts patient's quality of life in about 30%. Infodemiology studies the distribution and determinants of health information and misinformation over the internet allowing an analysis of internet search trends which provides a representative overview of people's needs, giving physicians a proper idea on how to approach patients. <h3>Methods</h3> Cross-sectional study from 7 countries using the online tool Google trends were the urticaria Relative Search Volume was compared to Disability-adjusted life year and Internet Penetration Rate from 2004 to 2022. <h3>Results</h3> The search trends included symptoms, etiology, classification, diagnosis and treatment. Urticaria was the first related topic found in all countries, except for itchy, nettle rash and hives in Indonesia, Germany and USA respectively. It is interesting that in most countries, when searching for urticaria, users used the term "hives" to refer to it. In most countries curves indicate an increasing trend search (p <0.001) related to symptoms and treatment, being more evident in Indonesia and Japan between 2014-2022. Some countries as Indonesia, United States and Germany show similar smooth patterns of increase in searches, whereas in Brazil and Japan a more sudden increase was seen. <h3>Conclusion</h3> There is an increasing global public interest in urticaria therefore the need of web-based high quality scientific information related to urticaria is so much needed to fight misinformation as the internet is a common source of health information.

An Analysis of Alopecia Related Content on Instagram and TikTok.

Social media platforms continue to grow in popularity and have become common sources of medical information and education for patients struggling with hair loss. We sought to determine the characteristics of popular hair loss related content on Instagram and TikTok. The top 9 most popular posts within 10 hair loss related hashtags on Instagram and TikTok were analyzed. Quantitative and qualitative analysis was used to evaluate posts from December 2020. The characteristic of the author, content category, and number of likes were analyzed for each post. Of 90 posts analyzed within Instagram, non-medical professional influencers created 66%, hair and wig companies created 29%, and medical professionals created 4%. Of 100 posts analyzed within TikTok, influencers created 38%, patients created 38%, hair and wig companies created 14%, and medical professionals created 10%. None of the top posts was created by board-certified dermatologists. This study was limited by the extent of data that can be collected from Instagram and TikTok. A majority of the content promoted hair care products, services, or treatments not substantiated by evidence-based medicine. Instagram and TikTok provide new opportunities for dermatologists to educate the general population on alopecia while simultaneously correcting misinformation. J Drugs Dermatol. 2022;21(12):1316-1321. doi:10.36849/JDD.6707.

Self-medication with ophthalmic drugs and its associated factors among ophthalmic patients attending three hospitals in Asmara, Eritrea: a cross-sectional study

ObjectiveTo assess the prevalence and practice of self-medication and its associated factors among ophthalmic patients.DesignAn analytical cross-sectional study design was employed.SettingThree hospitals inAsmara, Eritrea.ParticipantsSamples of ophthalmic outpatients aged >18 years...

Rheumatology expertise in advising immunocompromised healthcare workers: Insights from a survey of Australian rheumatologists.

Healthcare workers (HCW) with an inflammatory disease may be at increased risk of infections and their complications, however there is no evidence to guide specific measures to reduce the risk of immunocompromised HCW acquiring infection in the workplace. This cross-sectional study aimed to define the attitudes of rheumatologists and rheumatology trainees towards counselling immunocompromised healthcare workers about additional workplace precautions to minimise workplace risk of infection. A cross-sectional survey was administered via Zoom poll during a webinar held in August 2020. Participants were Victorian and Tasmanian members of the Australian Rheumatology Association, which includes consultant rheumatologists and rheumatology trainees. Descriptive statistics were used to analyse survey responses. Of the 52 participants, 41 provided care to at least one immunocompromised healthcare worker. 21 out of 52 participants estimated that the majority of these patients sought their advice about infection risk in the workplace. The most common source of information for counselling patients on workplace infection risks were colleagues (38/50). Participants were most confident in providing information on influenza and hepatitis but less confident in providing information in tuberculosis, shingles and COVID-19. Most participants believed employers of immunocompromised HCW should play a role in providing advice on managing infection risks in the workplace. Our study reveals a level of uncertainty and discomfort amongst rheumatologists in providing recommendations to immunocompromised healthcare workers about managing their workplace risk of infection. We recommend the development of a framework to guide the clinician in making individualised recommendations for immunocompromised HCW.

A COUNTRY-WIDE SURVEY ON KNOWLEDGE, ATTITUDE AND PRACTICE ABOUT CAUSES AND MANAGEMENT TOWARDS AMBLYOPIA AMONG SAUDI POPULATION

Objectives: To investigate the knowledge, attitude, and practice of Saudi population towards amblyopia on a national level. Methods: An observational cross-sectional study was conducted in 2018 among people who were aged ≥ 18 years from all regions of Saudi Arabia by using online self-administered questionnaire. The survey consisted of three main sections 1) sociodemographic data, personal and family history of eye diseases 2) knowledge questions and 3) attitude and practice questions. A survey link was used to collect data which also included an informed consent to be read and approved by the participant. Results: We interviewed 2001 Saudi nationals (24.7% men, 75.3% women), with mean age of 32.0 (±11.6) years.Seventy-three-point nine percent of the participants had no knowledge of amblyopia, while 26.1% had heard of it and knew its correct definition. Of those, 23.4% believe it can be attributed to genetics, 20.3% believe it can be caused by refractive errors and strabismus, and 45.9% are unsure whether it can be treated or cured. According to 25.8% of respondents, the media is the most common source of information on amblyopia. Eye exercises, surgery, medications and patching the good eye were perceived as treatment options by 21.3%, 20.3%, 17.0% and 17.5% of the participants, respectively. Although 49.2% are unaware of what age amblyopia can be treated, 22.8% believe that amblyopia can be treated after the age of 18. Conclusion: Our study showed that Saudi citizens have low level of awareness and inadequate knowledge about amblyopia, its causes, management and importance of early detection.

Use of management strategy evaluation to understand the value of citizen science in managing an iconic California recreational fishery

Data-limited fisheries present significant challenges to fisheries management around the world. Landings data represent the simplest and most common source of fishery information, but length data of harvested species can offer particularly useful insight into the strength of fishing pressure and the status of stocks. However, unbiased length data can be difficult and costly to collect, which highlights a need for understanding the utility of non-conventional data collection programs, such as those generated by community members and citizen science programs to improve management decision-making. In this study, our objective was to understand the value of citizen science for management using the iconic California recreational red abalone (Haliotis rufescens) dive fishery. To accomplish this, we employed management strategy evaluation (MSE) to simulate this benthic invertebrate fishery that was sampled by two different fishery independent survey protocols: a community science survey program led by trained volunteers and a professional science survey program led by a state agency. We subjected the data to a range of uncertainties, by including time-varying life history parameters, environmental variability, and effective sample size scenarios, to understand the management level consequences of each survey methodology. Our results show that community science program data collection can serve as a high-quality data source, can be linked directly to fisheries management decisions via a Harvest Control Rule (HCR), and can be a useful information source even in the absence of conventional data sources. Our results are specific to the California red abalone fishery, but they also highlight the potential broader value of community science data collection programs for improving information content of small-scale and recreational fisheries.

Discrepancies in patients' medication lists from pharmacies in Sweden: an interview study before the implementation of the Swedish National Medication List

BackgroundDiscrepancies in medication lists are common and can contribute to drug-related problems. This study was performed before the implementation of the National Medication List in Sweden, an intervention expected to improve the accuracy of medication lists.AimThe aim of the study was to examine the number and type of discrepancies in the medication list from pharmacies in Sweden. The secondary aim was to describe the information sources Swedish patients used as their medication lists and how confident they were with the information.MethodStructured interviews were conducted with patients at 13 community pharmacies in Sweden during the period October 5, 2020, to April 16, 2021. The printed medication list was reviewed together with the patient to identify any discrepancies and missing information.ResultsA total of 327 patients were included in the study (response rate 51%). The printed medication list from pharmacies was the most common information source for patients to know which medications to use. Two thirds (n = 215) of the patients had at least one discrepancy among their prescriptions and 32% (n = 106) were missing at least one prescription medication. Among all prescriptions (n = 2567) 10% (n = 264) were non-current prescriptions, 9% (n = 238) were duplicates and 3% (n = 88) had the wrong dose. The proportion of prescriptions with discrepancies differed between drug-groups.ConclusionThe discrepancies described in this study can have serious consequences, and results provide a baseline for studies after the implementation of the National Medication List.

Perceptions and use of complementary and alternative medicine in patients with precocious puberty.

Use of complementary and alternative medicine (CAM) is widespread. This study aimed to investigate the use of CAM in children with central precocious puberty (PP) who used gonadotropin-releasing hormone analog (GnRHa) treatment. Parents of 108 patients who were diagnosed as having PP were involved in the study. A questionnaire was administered to the parents during follow-ups. The patients were divided into two groups according to the use of CAM. Forty (37%) patients had used CAM. Parents who graduated from primary school tended not to use CAM (χ 2 =10.463; p=0.015). There was no other statistically significant difference between the sociodemographic features (p>0.05). The most common information source was physicians (40%). Seventy-five percentage of CAM users and 44.1% of non-CAM users knew/heard about herbal medicine (χ 2 =8.517; p=0.004) and herbal medicine was the most common type of CAM used. 80% of parents in the CAM group and 54.4% of parents in the non-CAM group knew at least one biologically based therapy that had estrogenic activity (χ 2 =6.082; p=0.014). Seventy-one percentage of parents in the CAM group and 29% of parents in the non-CAM group stated that they would consider using CAM in the future (χ 2 =16.979; p<0.001). The use of CAM among patients with PP is high. Although most CAM therapies are harmless, there may be adverse effects or drug interactions with current conventional treatment in children. Health professionals should be aware and inquire about the use and type of CAM, considering the medical history at every patient encounter.

Use of traditional and complementary medicine for COVID 19 prophylaxis among healthcare professionals and students in Jordan: A cross-sectional study

IntroductionThere is inadequate evidence to recommend the use of any traditional and complementary medicine (T&CM) methods such as vitamin, mineral, herbal or other dietary supplements to prevent or treat COVID 19. Members of the medical team are particularly at risk of exposure to high viral load of coronavirus. They have also the best access to professional information regarding disease treatment and prophylaxis and disseminate such knowledge.The aim of the study was to assess the prevalence of use of T&CM for the prophylaxis of COVID 19 among the healthcare professionals and students in Jordan, along with the most common types and the factors associated with T&CM use.MethodologyA cross-sectional study of T&CM use was conducted in Jordan using a snowball sampling method to distribute Google Forms and to enrol participants during coronavirus outbreak between June 10, 2021, and August 28, 2021. The study included healthcare professionals or students who consented to participate in the survey. The survey excluded those participants who had filled the questionnaire at least once or were pregnant/breast-feeding at the time of the study. The questionnaire consisted of 29 items, including screening, checkbox, dichotomous, matrix and open-ended questions.ResultsThe response rate was 97.1%. Out of 560 study respondents, 359 (64.1%) reported using T&CM for COVID 19 prevention. Vitamins and nutrients were consumed by almost half (48.4%) of study participants, while nonpharmacological methods and herbal remedies were consumed by 35.2% and 25.2%, respectively. The most common source of information regarding T&CM use for COVID 19 prophylaxis included scientific publications (59.5%), followed by disease treatment guidelines (38.0%) and social media (32.3%). Adverse effects were reported by 8.5% and possible adverse effects were reported by another 8.5% of participants. The T&CM use was associated with working in contact with COVID 19 patients (OR: 1.625 (95% CI 1.047–2.523) (P = 0.03) and having a colleague as a source of information (OR: 1.720 (95% CI 1.026–2.883) (P = 0.04).ConclusionsThe prevalence of T&CM use for COVID 19 prevention among healthcare professionals and students in Jordan is high, with a significant proportion of participants reporting adverse effects. There is an urgent need for further research toward efficacy and safety of T&CM in COVID 19 prophylaxis as well as development of appropriate public health policy on this issue specific to each country.