Osteotarthritis (OA) is one of the most common inflammatory joint diseases and rheumatic musculoskeletal conditions worldwide. OA is the 11th most disabling disease in the world. Knee OA is the most common joint condition, accounting for 83% of cases out of 4% of the global population. Diagnosing OA typically begins with history taking of patient, physical examinations, and supportive examination guided by the Indonesian Rheumatology Association. WOMAC index is a widely used patient-reported tool to assess pain, stiffness, and physical function in knee OA patients. Additionallly, knee OA is often evaluated using anteroposterior radiographs to identify osteophytes and joint space narrowing. The Kellgren-Lawrence scoring system is commonly employed to classify radiographis severity. Knee OA is a chronic condition that impairs daily activities and significantly diminishes quality of life (QoL). The SF-36 questionnaire is frequently used to evaluate QoL, providing a holistic view of health status and guiding patient management. Based on the high prevalence of knee OA, the variety of instruments used in determining the severity of OA both clinically and radiologically, the variety of risk factors for OA events, and the lack of research related to the relationship between clinical and radiological images with the quality of life of patients, researchers will analyse the correlation between radiological images (Kellgren-Lawrence) and clinical images (WOMAC) with QoL (SF-36). However, more extensive and in-depth study is still required to determine which risk factors have a significant impact on the correlation of this three components in knee OA patients.
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