SummaryA cold water extract of leaves of the plant Symphytum officiale was given to mice bearing spontaneous or transplanted tumors. The tests involved 73 control and 52 experimental mice bearing spontaneous mammary tumors of various initial sizes, and 71 control and 63 experimental animals bearing transplanted mammary tumors. Survival time of the spontaneous tumor mice that received comfrey extract was increased an average of 59% as compared with the controls. In the transplanted tumor tests, tumor weight at autopsy averaged 24% less in the comfrey extract mice as compared with the controls. These differences between control and experimental groups are statistically significant.