Combination Of Chinese Medicine Research Articles

Chinese Medicine Combined with Adipose Tissue-Derived Mesenchymal Stem Cells: A New Promising Aspect of Integrative Medicine.

Adipose tissue-derived mesenchymal stem cells (ADSCs) are crucially involved in various biological processes because of their self-renewal, multi-differentiation, and immunomodulatory activities. Some ADSC's characteristics have been associated with the basic theory of Chinese medicine (CM), especially the Meridian theory. CM can improve the biological properties of ADSCs to facilitate their use in injury treatment, restore immune homeostasis, and inhibit inflammatory responses. Therefore, the combination of CM and ADSCs may be a new promising research direction in integrative medicine of China. This review summarizes the association between CM and ADSCs to assess the potential application value of their combination against various diseases.

Comparative analysis of the therapeutic effect of traditional chinese medicine and western medicine on ROU

The prevalence of recurrent oral ulcer is as high as 50%. It is generally more prevalent in women than in men, and it typically occurs between the ages of 10 and 30. Surveys indicate that at least 10% to 25% of people have experienced this disease. This disease is characterized by cyclical, recurrent, self-limited symptoms of burning pain. Currently, there is no specific drug treatment available for recurrent oral ulcers, making it a major challenge in the academic field. This paper examines the efficacy of different medications in treating recurrent oral ulcers through literature review, data extraction, and quality evaluation. The study concludes that the most effective treatment approach is a combination of Chinese and Western medicine. The combination of Chinese and western medicine drugs has shown significant effects in reducing the recurrence rate of the disease, as well as improving oral flora and other aspects. Furthermore, the therapeutic effect of integrated Chinese and western medicine is considered to be superior.

Insomnia Disease Treatment in Acupuncture - A Case Study in Bangladesh

As of its popularity in eastern medicine, acupuncture treatment may help insomniacs get a good night's rest. Insomnia seems to be on the rise in the contemporary world, negatively impacting not just people's capacity to function but also their quality of life. Even if pharmaceutical therapy is beneficial, it often comes with serious side effects. The practice of acupuncture to treat insomnia has a long history in China and has recently gained widespread acceptance in the West. Numerous studies have demonstrated therapeutic uses of acupuncture for the treatment of insomnia, with many also discussing the possible processes behind the therapy. An attempt at a comprehensive overview of the relevant research will be made in this section. This research was an observational study conducted in Dhaka at Suo-Xi Hospital, Shann Tower, Chamelibag, Shantinagar Dhaka, Bangladesh. A 28-year-old man presented to the clinic complaining of sleeplessness dating back three years. We used a combination of Chinese medicine and acupuncture on the patient's scalp to help them sleep better. Excellent outcomes were found in the study's subsequent follow-up. After 12 days of acupuncture, the sleeplessness that had plagued the patient for three years began to subside. Treatment with acupuncture has been shown to aid in the functional recovery of insomnia sufferers.

Relief and improvement of traditional Chinese medicine combined with exercise therapy in sports dance sports injury disorder from a biomechanical perspective

Among all kinds of sports, competitive sports with graceful movements as the main content are deeply loved by athletes. However, in the practice of sports dance, due to insufficient skills, incorrect movements, inattention and other factors, it is easy to cause sports injuries, which affects the effect of sports dance teaching. Therefore, the research and application of the alleviation and improvement of sports injury disorders are becoming more and more important. Although there are many researches and applied studies on the mitigation and improvement of sports injury disorders in sports dance, the existing research still needs to be supplemented. In this paper, a combination of traditional Chinese medicine and exercise therapy has been discussed. First, the relevant theoretical overview and related work were organized, and the sports dance movement was introduced. Then, based on the modeling of sports injury disorder, related algorithms were written, and the elements of mitigation and improvement of sports injury disorder, sports injury elements of sports dance, and elements of traditional Chinese medicine combined with exercise therapy were introduced. In the fourth part, a study on the improvement of alleviation and improvement of sports injury disorder in sports dance was carried out. In this paper, various algorithms were used to study the topic of Chinese medicine combined with exercise therapy in the mitigation and improvement of sports dance injury disorders, and the experiments were summarized and discussed. The results of the study showed that the mitigation improvement and application study of sports injury impairment in sports dance constructed in this paper can reduce the incidence of sports injury by 4.62%.

Efficacy and safety of Chinese herbal medicines combined with biomedicine in the treatment of idiopathic membranous nephropathy: a systematic review and network meta-analysis.

Chinese herbal medicines have been extensively used to treat idiopathic membranous nephropathy (IMN). However, their efficacy and safety remain uncertain. Therefore, this study employed a network meta-analysis to evaluate the efficacy and safety of various Chinese herbal medicines in combination with biomedicines for treating IMN. A comprehensive literature search was performed across several databases, including PubMed, EMBASE, Web of Science, Cochrane Library, China National Knowledge Infrastructure (CNKI), WanFang Data, VIP Database, and Chinese Biomedical Literature Database (CBM), to identify randomized controlled trials (RCTs) concerning the treatment of IMN using a combination of Chinese herbal medicines and biomedicine, up to 31 May 2024. Two researchers independently conducted the literature screening and data extraction. The quality of the included studies was assessed using the Cochrane quality review manual, and Stata 14.2 software was employed for network meta-analysis. A total of 31 RCTs involving 2195 IMN patients and 15 different Chinese herbal medicines were analyzed. The network meta-analysis revealed that QQC + BM (84.7%) was the most effective in reducing 24-hour urinary protein. For improving serum albumin, HZC + BM (86%) was the most effective. LGT + BM (77.2%) was the best for enhancing serum creatinine levels. MXC + BM demonstrated the highest effectiveness in lowering total cholesterol (89%) and triglycerides (97%). Lastly, WZC + BM (90.8%) was the most effective in reducing the incidence of adverse reactions. BM. The current evidence suggests that integrating Chinese herbal medicines with biomedicine may provide significant benefits in treating IMN. Specifically, QQC + BM appears to be the most effective in reducing 24-hour urinary protein, HZC + BM seems to excel in improving serum albumin levels, MXC + BM is noted for its effectiveness in lowering triglycerides and total cholesterol, LGT + BM is optimal for reducing serum creatinine, and WZC + BM shows the lowest rate of adverse reactions. Nevertheless, due to limitations in the quantity and quality of the included studies, further validation of these conclusions is necessary. [https://www.crd.york.ac.uk/prospero/display_record.php?ID=CRD42024561028], identifier [CRD42024561028].

A Case of Peritoneal Dialysis-associated Encapsulated Peritoneal Sclerosis Treated with a Combination of Chinese and Western Medicine

A Case of Peritoneal Dialysis-associated Encapsulated Peritoneal Sclerosis Treated with a Combination of Chinese and Western Medicine

Research Progress in Integrated Chinese and Western Medicine Health Management for School-Age Children with Asthma

Objective: The purpose of this study is to investigate the application of Chinese and Western medicine in the health management of school-age children with asthma and its research progress, with a view to providing a more comprehensive and effective management strategy for the clinic. Methods: Using the method of literature review, this study systematically searched and analyzed the relevant studies on the combination of Chinese and Western medicine in the health management of school-aged children with asthma in recent years, focusing on Chinese medicine treatment, Western medicine treatment, and the combined health management of Chinese and Western medicine. Results: Chinese medicine treatment, Western medicine treatment, and the health management mode of combining Chinese and Western medicine showed unique advantages in school-age asthmatic children. Through the comprehensive use of Chinese medicine’s diagnosis and treatment, Chinese medicine conditioning, Chinese medicine characteristic therapy, and Western medicine’s modern medical methods, it not only effectively relieved asthma symptoms but also significantly improved the quality of life of the children. At the same time, this management mode also focuses on the psychological guidance and family care of the children, forming an all-round and multi-level health management system. Conclusion: The health management strategy of combining Chinese and Western medicine has a broad application prospect in school-age asthmatic children, and its specific interventions and mechanisms of action should be further studied to provide more scientific and systematic guidance for clinical practice.

Traditional Chinese medicine combined with chemotherapy in the treatment of advanced non-small cell lung cancer: key drug screening and mechanism analysis.

In the course of clinical treatment for anti-tumor, the combination of traditional Chinese medicine (TCM) and other treatment schemes can reduce toxicity and increase efficiency. The purpose of this paper is to find out the key TCM and effective components for the treatment of non-small cell lung cancer (NSCLC) and analyze its therapeutic mechanism by analyzing the prescription of TCM combined with chemotherapy for NSCLC. Firstly, the prescriptions of TCM in the randomized controlled trials combined with chemotherapy for NSCLC were collected, and the core TCM was screened by frequency statistics, association rule analysis, and cluster analysis. Then, the intersection targets of the potential effects of NSCLC and core Chinese medicine were collected, and PPI analysis and enrichment analysis were performed on the intersection targets to screen the core targets, components, and pathways. The core components were verified by molecular docking and cell experiments. In this study, 269 prescriptions were collected, among which the frequency of medication for Astragalus membranaceus (HQ, in Chinese), Wolfiporia cocos (FL, in Chinese), and Atractylodes macrocephala (BZ, in Chinese) was over 100. Association rule analysis showed that they were highly correlated and clustered into the same category in cluster analysis. Their core components were quercetin, kaempferol, and isorhamnetin. The molecular docking results of the core components with the core targets AKT1 and EGFR obtained by PPI network analysis showed that they could bind stably. KEGG analysis screened 110 pathways including PI3K-Akt; the results of CCK-8 showed that quercetin, kaempferol, and isorhamnetin could effectively inhibit the proliferation of A549 cells, and isorhamnetin had the best inhibitory effect. Isorhamnetin can inhibit the migration and invasion of A549 cells, induce apoptosis and G1 phase arrest, and decrease the expression of P-PI3K and P-AKT in A549 cells. In a word, the key TCM for the treatment of NSCLC includes HQ, FL, and BZ. and its key components quercetin, kaempferol, and isorhamnetin have potential therapeutic effects on NSCLC according to the research results.

Liver cirrhosis: current status and treatment options using western or traditional Chinese medicine.

Liver cirrhosis arises from liver fibrosis and necroinflammation caused by various mechanisms of hepatic injury. It is a prevalent condition in clinical practice characterized by hepatocellular dysfunction, portal hypertension, and associated complications. Despite its common occurrence, the etiology and pathogenesis of liver cirrhosis remain incompletely understood, posing a significant health threat. Effective prevention of its onset and progression is paramount in medical research. Symptoms often include discomfort in the liver area, while complications such as sarcopenia, hepatic encephalopathy, ascites, upper gastrointestinal bleeding, and infection can arise. While the efficacy of Western medicine in treating liver cirrhosis is uncertain, Chinese medicine offers distinct advantages. This review explores advancements in liver cirrhosis treatment encompassing non-pharmacological and pharmacological modalities. Chinese medicine interventions, including Chinese medicine decoctions, Chinese patent medicines, and acupuncture, exhibit notable efficacy in cirrhosis reversal and offer improved prognoses. Nowadays, the combination of Chinese and Western medicine in the treatment of liver cirrhosis also has considerable advantages, which is worthy of further research and clinical promotion. Standardized treatment protocols based on these findings hold significant clinical implications.

Combined traditional Chinese medicine therapy for the treatment of infertility with polycystic ovary syndrome: A network meta-analysis of randomized controlled trials.

Polycystic ovary syndrome (PCOS) infertility has attracted great attention from researchers due to its high incidence. Numerous studies have shown that Chinese medicine is effective in treating this disease, but there is a wide variety of Chinese medicine therapies available, and there is a lack of comparative evaluation of the efficacy of various Chinese medicine combination therapies in the clinic, which requires further in-depth exploration. This study aims to evaluate the efficacy of a combined traditional Chinese medicine (TCM) therapy for the treatment of infertility with PCOS using network meta-analysis (NMA). In PubMed, web of Science, Cochrane Library, Embase, China Knowledge Network, Wanfang Data, VIP Database, China Biomedical Literature Database (SinoMed) databases, searchs were conducted for information about the randomized controlled trials (RCTs) of combined TCM therapy for the treatment of infertility with PCOS. Quality evaluation was performed using the Cochrane 5.3 risk of bias assessment tool, and NMA using Stata 16.0. This study comprised 28 RCTs using 8 combined TCM therapies in total. The results of the NMA showed that moxibustion + herbal, fire acupuncture + herbal, acupuncture + herbal, electroacupuncture + herbal, and acupoint application + herbal improved the clinical pregnancy rate better than acupuncture, herbal, and western medicines monotherapy (P < .05). Additionally, ear point pressure + herbal enema + herbal, acupuncture and moxibustion + herbal, fire acupuncture + herbal, and acupuncture + herbal improved the ovulation rate better than acupuncture, herbal, and western medicines monotherapy (P < .05). Moxibustion + herbal, fire acupuncture + herbal, and acupuncture + herbal are the 3 most effective therapies for improving the clinical pregnancy rate. Fire acupuncture + herbal, acupuncture + herbal, and ear point pressure + herbal enema + herbal are the 3 most effective therapies for improving the ovulation rate. The combined TCM therapy demonstrated better efficacy for the treatment of infertility with PCOS compared to acupuncture, herbal, and western medicines monotherapy. However, the optimal treatment therapy varied depending on the outcome indicators. Further large sample, high-quality, and standardized RCTs are needed to verify these findings.

Network Meta-analysis of Chinese patent medicines in treatment of chronic pulmonary heart disease

Network Meta-analysis was performed to compare the efficacy and safety of Chinese patent medicines in treating chronic pulmonary heart disease. CNKI, VIP, Wanfang, SinoMed, PubMed, Web of Science, EMbase, and Cochrane Library were searched for randomized controlled trial(RCT) of treating chronic pulmonary heart disease with Chinese patent medicines with the time interval from inception to December 2023. The Cochrane risk-of-bias tool was used for quality assessment of the included articles. RevMan 5.4 and Stata 17.0 were employed to establish the risk of bias map and perform the network Meta-analysis, respectively. Ultimately, a total of 95 RCTs involving 8 787 cases and 11 different Chinese patent medicines were included. Network Meta-analysis yielded the following results based on the surface under the cumulative ranking curve(SUCRA).(1)In terms of cardiac function improves clinical total effective rate, SUCRA the top three were Wenxin Granules + conventional western medicine, Tongxinluo Capsules + conventional western medicine, and Qishen Yiqi Dropping Pills + conventional western medicine.(2)For improving forced expiratory volume in the first se-cond(FEV1), SUCRA the top three were Danting Feixin Granules + conventional western medicine, Tongxinluo Capsules + conventional western medicine, and Bufei Huoxue Capsules + conventional western medicine.(3)Regarding increasing the FEV1/forced vital capacity(FVC%) value, SUCRA the top three were Qili Qiangxin Capsules + conventional western medicine, Shexiang Baoxin Pills + conventional western medicine, and Qishen Yiqi Dropping Pills + conventional western medicine.(4)In terms of increasing the partial pressure of oxygen(PaO_2), SUCRA the top three were Qili Qiangxin Capsules + conventional western medicine, Qishen Yiqi Dropping Pills + conventional western medicine, and Shexiang Baoxin Pills + conventional western medicine.(5)In terms of reducing the partial pressure of carbon dioxide(PaCO_2), SUCRA the top three were Tongxinluo Capsules + conventional western medicine, Qishen Yiqi Dropping Pills + conventional western medicine, and Shexiang Baoxin Pills + conventional western medicine.(6)In terms of increasing left ventricular ejection fraction(LVEF), SUCRA the top three were Bufei Huoxue Capsules + conventional western medicine, Qishen Yiqi Dropping Pills + conventional western medicine, and Shexiang Baoxin Pills + conventional western medicine.(7)In terms of decreasing brain natriu-retic peptide(BNP), SUCRA the top three were Compound Danshen Dropping Pills + conventional western medicine, Qili Qiangxin Capsules + conventional western medicine, and Tongxinluo Capsules + conventional western medicine.(8)In terms of improving the hematocrit level, SUCRA the top three were Qishen Yiqi Dropping Pills + conventional western medicine, Compound Danshen Dropping Pills + conventional western medicine, and Tongxinluo Capsules + conventional western medicine. In terms of safety, 26 RCTs reported adverse reactions, which primarily involved the circulatory and digestive systems. The combination of Chinese patent medicines with conventional western medicine has demonstrated enhanced therapeutic effects on chronic pulmonary heart disease. However, due to the varying quality and sample sizes of included studies and the absence of direct comparisons between Chinese patent medicines, the conclusions should be further validated by multicenter studies with larger sample sizes and higher methodological rigor.

Progress of Chinese and Western Medicine Research on Polycystic Ovary Syndrome

Polycystic ovary syndrome (PCOS) is a common clinical disease of reproductive endocrine hormone abnormalities and metabolic disorders, with a variety of clinical symptoms and complex etiology. Recent studies have shown that genetics, reproductive endocrine hormones, inflammatory factors, intestinal flora, microRNAs, signal transduction pathways and insulin resistance are closely related to the development of PCOS. Regarding the treatment modalities of PCOS, Western medicine mostly focuses on symptomatic treatment for elevated androgens, ovulation abnormalities, menstrual irregularities and insulin resistance. Chinese medicine focuses on conditioning, and adopts Chinese medicine, acupuncture and needle-medicine combination for different identification and typing through the idea of holistic view. The combination of Chinese and Western medicine gives full play to the advantages between modern medicine and traditional medicine, and combines Western medicine with Chinese medicine for symptomatic treatment, which is a holistic approach and has significant therapeutic effects. Therefore, this paper provides an overview of the research on the etiology and pathogenesis of PCOS in recent years, as well as an overview of the treatment of PCOS by Western medicine, Chinese medicine and the combination of Chinese and Western medicine.

A Case Report on Treating Progressive Supranuclear Palsy with a Combination of Chinese and Western Medicine

A case of progressive supranuclear palsy in a 66-year-old woman is presented. The patient complained of “progressive stiffness of both lower limbs for five years, accompanied by choking and coughing for more than 1 year,” and was diagnosed with paralysis in traditional Chinese medicine (TCM), which was characterized by a deficiency of liver and kidney, and phlegm and blood stasis blocking the collaterals. Western medicine diagnosed it as progressive supranuclear palsy. The patient was diagnosed with “Parkinson’s disease” several times in the past and was given “polybasic hydrazide” and “amantadine hydrochloride tablets,” etc. The patient did not have significant symptomatic relief, so she sought further treatment with a combination of traditional Chinese and Western medicine. Based on the concept of deficiency and excess, this disease is categorized as a paralytic disease in Chinese medicine, and the onset of the disease is closely related to the deficiency of the body after a long period of illness, with wind, phlegm, blood stasis, and deficiency as the main pathogenetic mechanism. The treatment is based on the combination of disease and evidence, with traditional Chinese medicine and acupuncture as the main treatments, supplemented by intermediate-frequency pulsed electrical stimulation, transcranial repetitive magnetic stimulation, medicated canisters, wax therapy, traditional Chinese medicine guasha, and acupoint injections. Western medicine is based on symptomatic treatment, and the patient’s symptoms were relieved significantly after the combination of Chinese and Western medicine.

Exploring the Underlying Mechanisms of Qingxing Granules Treating H1N1 Influenza Based on Network Pharmacology and Experimental Validation.

H1N1 is one of the major subtypes of influenza A virus (IAV) that causes seasonal influenza, posing a serious threat to human health. A traditional Chinese medicine combination called Qingxing granules (QX) is utilized clinically to treat epidemic influenza. However, its chemical components are complex, and the potential pharmacological mechanisms are still unknown. QX's effective components were gathered from the TCMSP database based on two criteria: drug-likeness (DL ≥ 0.18) and oral bioavailability (OB ≥ 30%). SwissADME was used to predict potential targets of effective components, and Cytoscape was used to create a "Herb-Component-Target" network for QX. In addition, targets associated with H1N1 were gathered from the databases GeneCards, OMIM, and GEO. Targets associated with autophagy were retrieved from the KEGG, HAMdb, and HADb databases. Intersection targets for QX, H1N1 influenza, and autophagy were identified using Venn diagrams. Afterward, key targets were screened using Cytoscape's protein-protein interaction networks built using the database STRING. Biological functions and signaling pathways of overlapping targets were observed through GO analysis and KEGG enrichment analysis. The main chemical components of QX were determined by high-performance liquid chromatography (HPLC), followed by molecular docking. Finally, the mechanism of QX in treating H1N1 was validated through animal experiments. A total of 786 potential targets and 91 effective components of QX were identified. There were 5420 targets related to H1N1 and 821 autophagy-related targets. The intersection of all targets of QX, H1N1, and autophagy yielded 75 intersecting targets. Ultimately, 10 core targets were selected: BCL2, CASP3, NFKB1, MTOR, JUN, TNF, HSP90AA1, EGFR, HIF1A, and MAPK3. Identification of the main chemical components of QX by HPLC resulted in the separation of seven marker ingredients within 195 min, which are amygdalin, puerarin, baicalin, phillyrin, wogonoside, baicalein, and wogonin. Molecular docking results showed that BCL2, CASP3, NFKB1, and MTOR could bind well with the compounds. In animal studies, QX reduced the degenerative alterations in the lung tissue of H1N1-infected mice by upregulating the expression of p-mTOR/mTOR and p62 and downregulating the expression of LC3, which inhibited autophagy. According to this study's network pharmacology analysis and experimental confirmation, QX may be able to treat H1N1 infection by regulating autophagy, lowering the expression of LC3, and increasing the expression of p62 and p-mTOR/mTOR.

Research Progress of Cholestatic Liver Disease-Related Pruritus in Chinese Medicine and Western Medicine

AbstractPruritus is common in cholestatic liver disease, with a high clinical incidence rate and complex pathogenesis. Accumulation of potential pruritus inducers such as steroids, bile acids, and lysophosphatidic acid in the systemic circulation is the main cause of pruritus in cholestatic liver disease. Currently, clinical treatment of cholestatic liver disease-related pruritus mainly includes medication, intervention therapy, and some experimental methods. However, there are still problems, such as unclear pathological mechanisms and unsatisfactory treatment responses in some patients with cholestatic liver disease-related pruritus. Effective treatment for patients still faces challenges. By extensively screening patients' plasma (and/or bile) samples through clinical trials, potential pruritus inducers can be identified comprehensively, which can provide a deeper understanding of the itch signaling pathways in cholestatic liver disease and a basis for the development of treatment strategies. Traditional Chinese medicine (TCM) has shown certain characteristics and advantages in clinical treatment. Based on the etiology and pathogenesis, external application, internal administration, and TCM-specific therapies have achieved good clinical efficacy. Similarly, the combination of Chinese medicine and Western medicine has also achieved more effective treatment for patients with cholestatic liver disease-related pruritus. This article will introduce the latest progress in the study of pruritus inducers in cholestatic liver disease and its treatment in TCM and Western medicine.

Combination of Chinese and Western Medicine: Molnupiravir and Lianhua Qingwen in the Treatment of Novel Coronavirus Pneumonia (COVID-19)

Objective: This study aimed to assess the effectiveness of Molnupiravir and Lianhua Qingwen in treating patients with novel coronavirus pneumonia (COVID-19). Materials and Methods: We conducted a study involving 14 cases of COVID-19 infection within a unit group in Laos. During the treatment regimen, these patients received the antiviral drugs Molnupiravir and Lianhua Qingwen as prescribed. We utilized laboratory results of viral nucleic acid tests as observational parameters and statistically analyzed the data using SPSS 26.0 software (linear regression analysis). Our data analysis aimed to determine if there were significant differences in the Ct values of the N gene and ORF1ab gene of SARS-CoV-2 before and after treatment. Results: The results indicated statistically significant differences in the N gene (t =﹣7.014, P &lt; 0.001) and ORF1ab gene (t =﹣7.398, P &lt; 0.001). Post-treatment, the values of the N gene and ORF1ab gene were significantly higher than their pre-treatment values, signifying that the combined utilization of Molnupiravir and Lianhua Qingwen had a substantial impact on the treatment of COVID-19. Conclusion: Molnupiravir and Lianhua Qingwen effectively inhibited the replication of SARS-CoV-2, resulting in a marked improvement in the clinical symptoms of the patients. Laboratory test results also indicated a significant reduction in viral load. These findings provide substantial evidence supporting the efficacy of the combination of Molnupiravir and Lianhua Qingwen in the treatment of COVID-19.

The effects of Nardosinone on levodopa intervention in the treatment of Parkinson's disease

BackgroundThe roots and rhizomes of Nardostachys jatamansi DC. are reported to be useful for the treatment of Parkinson's disease (PD). Previous research has also shown that Nardosinone, the main active component isolated from Nardostachys jatamansi DC., exhibits the potential to treat PD. Aim of the studyTo investigate how the effects of Nardosinone could assist levodopa in the treatment of PD, how this process changes the intestinal flora, and to explore the effective forms of Nardosinone in the intestinal flora. Material and methodsWe used behavioral experiments, and hematoxylin-eosin staining and immunohistochemical staining, to investigate the effects of a combination of Nardosinone and levodopa on rotenone-induced PD rats. In addition, we used LC/MS-MS to determine the levels of levodopa, 5-hydroxytryptamine, dopamine and its metabolite 3, 4-dihydroxyphenylacetic acid, and homovanillic acid, to investigate the effect of the intestinal flora on co-administration in the treatment of PD. LC/MS-MS was also used to detect the metabolites of Nardosinone on the gastrointestinal tract and intestinal flora. ResultsThe behavioral disorders and neuronal damage associated with PD were significantly improved following the co-administration. Analysis also revealed that the co-administration increased the levels of five neurotransmitters in the striatum, plasma and feces. In vitro experiments further demonstrated that the levels of dopamine and levodopa were increased in the intestinal flora. In total, five metabolites of Nardosinone were identified. ConclusionOur findings indicate that Nardosinone and its metabolites might act as a potential adjutant to enhance the efficacy of levodopa via the intestinal flora, thus expanding the therapeutic potential of the combination of Chinese and Western medicine as a treatment method for PD.

A review of chemotherapeutic drugs-induced arrhythmia and potential intervention with traditional Chinese medicines.

Significant advances in chemotherapy drugs have reduced mortality in patients with malignant tumors. However, chemotherapy-related cardiotoxicity increases the morbidity and mortality of patients, and has become the second leading cause of death after tumor recurrence, which has received more and more attention in recent years. Arrhythmia is one of the common types of chemotherapy-induced cardiotoxicity, and has become a new risk related to chemotherapy treatment, which seriously affects the therapeutic outcome in patients. Traditional Chinese medicine has experienced thousands of years of clinical practice in China, and has accumulated a wealth of medical theories and treatment formulas, which has unique advantages in the prevention and treatment of malignant diseases. Traditional Chinese medicine may reduce the arrhythmic toxicity caused by chemotherapy without affecting the anti-cancer effect. This paper mainly discussed the types and pathogenesis of secondary chemotherapeutic drug-induced arrhythmia (CDIA), and summarized the studies on Chinese medicine compounds, Chinese medicine Combination Formula and Chinese medicine injection that may be beneficial in intervention with secondary CDIA including atrial fibrillation, ventricular arrhythmia and sinus bradycardia, in order to provide reference for clinical prevention and treatment of chemotherapy-induced arrhythmias.

An overview of remedial treatment for sudden hearing loss

In the acute phase of sudden hearing loss, in patients for whom two weeks of standardized treatment is ineffective or unsatisfactory, or patients for whom the condition has accumulated for more than three weeks, remedial treatment for about 1 week-1 month can be actively pursued to provide an opportunity for hearing recovery. The mainstay of remedial therapy is intratympanic and retro auricular hormone injections. If the disease has progressed beyond 6 weeks and there is still no significant improvement with local hormone injections, the overall efficacy of the treatment can be improved by a combination of Chinese and Western medicine, such as hyperbaric oxygen chambers, acupuncture, and massage (tui na). However, remedial treatments combining Chinese and Western medicine have not been standardized, and attention should be paid to the diagnosis and treatment during the remedial period.

Evaluation and Monitoring System for Exercise Rehabilitation Based on Combined Chinese and Western Medicine Technology

INTRODUCTION: Developing exercise rehabilitation assessment and monitoring systems is essential in rehabilitation medicine. Introduces a sports rehabilitation assessment and monitoring system based on combining Chinese and Western medicine technology, aiming to integrate traditional Chinese and Western medicine theory and modern Western medicine technology to provide more comprehensive and personalized rehabilitation services. Through the systematic integration of technologies, the author is committed to building an efficient and precise rehabilitation system to provide patients with more scientific and practical rehabilitation programs. OBJECTIVE: The research system employs various sensor technologies, including motion capture devices, biosensors, and pulse recognition technology, by combining Chinese and Western medicine. The motion capture device enables real-time monitoring of the patient's movement trajectory, joint mobility, and other physiological indicators; the biosensor collects the patient's physiological data, such as heart rate and blood pressure. Meanwhile, Chinese and Western medicine pulse recognition technology was introduced to obtain pulse information specific to Chinese and Western medicine to provide more comprehensive data support for rehabilitation assessment. Integrating these technologies, a multi-level and multi-dimensional rehabilitation assessment system was established. METHODS: This study aims to improve the accuracy and personalization of the rehabilitation assessment and to tailor a rehabilitation plan more in line with the patient's actual situation. Through the combination of Chinese and Western medicine techniques, it aims to break the single perspective of traditional rehabilitation assessment and make the rehabilitation plan closer to the physiological characteristics and pathological state of the patients as well as the needs of the combination of Chinese and Western medicine in the identification and treatment. RESULTS: The system has achieved remarkable results in practical application. The accurate monitoring of the motion capture device provides a more comprehensive understanding of the patient's motor status and accurately analyzes the rehabilitation progress. At the same time, the data collection of biosensors provides doctors with more detailed physiological information, enabling them to formulate rehabilitation plans more comprehensively. The introduction of combined Chinese and Western medicine pulse recognition technology adds a unique auxiliary diagnostic tool of collaborative Chinese and Western medicine to the rehabilitation assessment and improves the personalized level of the rehabilitation plan. CONCLUSION: The sports rehabilitation assessment and monitoring system combining Chinese and Western medicine technology brings new ideas and methods for developing rehabilitation medicine. By fully utilizing the advantages of modern technology and traditional medical knowledge, a comprehensive and in-depth rehabilitation assessment system was constructed to provide patients with more scientific and caring rehabilitation services. Future research will optimize the system's performance and promote the broad application of integrated Chinese and Western medicine technology in rehabilitation.