Purpose: To assess the color stability of one- shaded structurally- colored resin composite compared to conventional multi- shaded one. Subjects and methods: Thirty- two disc- like specimens from one- shaded structurally- colored resin composite (Omnichroma, Tokuyama Dental); Group I, or conventional resin composite (Filtek Z350, 3M ESPE); Group II were prepared, with equal allocation ratio (i.e.: n= 16). Samples were left in coffee then by using spectrophotometry, colors for all specimens were assessed in (CIE) Lab values; before (baseline) and 30 days later. Substitution in the (after - before) equation was performed to obtain the color change (ΔE); to detect color change for each specimen. Data was tabulated & statistically analyzed. Results: One- shaded structurally- colored resin composite (Omnichroma) showed statistically significant (p ≤ 0.05) color stability in comparison to conventional resin composite (Filtek Z350). Conclusion: One- shaded structurally- colored resin composite (Omnichroma) proved better than conventional resin composite (Filtek Z350) regarding color stability. Esthetic color matching, therefore, could be easily obtained and maintained.