In-vitro and in-vivo examinations to investigate the influence of one (1D)- and two-dimensional (2D) parallel acquisition techniques (PAT) on contrast-to-noise ratio (CNR) and image quality for bright-lumen 3D MR colonography. In-vitro measurements were performed on a 1.5 T whole-body MR scanner (MAGNETOM AVANTO(R), Siemens AG, Erlangen) with a standard spoiled 3D gradient-echo (3D GRE) sequence and a volume interpolated 3D GRE (VIBE) sequence using a home-built colon phantom. The relative CNR was determined and image quality evaluated for different acceleration factors (PAT factors). A bright-lumen 3D MR colonography with PAT factors 2, 3, 4 and 6 was performed on a 39-year-old volunteer. The 3D data sets were compared with regard to image quality. The mean relative CNR values for the in-vitro measurements were 1, 0.81, 0.73, 0.52 and 0.4 (3D GRE) and 1, 0.8, 0.65, 0.45 and 0.3 (VIBE) for the PAT factors 1, 2, 3, 4 and 6, respectively. Residual aliasing artifacts not affecting image quality in a distinct manner were visible for 2D PAT, especially for the VIBE sequence. Increasing the PAT factor up to 6 and decreasing the acquisition time down to 10 seconds for the bright-lumen 3D MR colonography could achieve adequate image quality with significantly reduced image artifacts caused by peristalsis and pulsations. Even for high PAT factors up to 6, 2D PAT only leads to a moderate CNR loss. For a 3D MR colonography, distinct shorter acquisition times can be achieved with identical resolution.