The purpose of this article is twofold: to give a sense of the current lay of the land in the preparation of mathematics graduate student teaching assistants (TAs) and to describe the collegiate mathematics education research base informing the next generation of college mathematics instructor preparation. We anchor discussion in three common types of TA preparation programs, each represented in one of the quotes above. Notably, the first quote represents a sink or swim experience that is becoming rare in US PhD-granting mathematics departments. Preparation of TAs for their instructional roles has blossomed in the last twenty years. The second quote is representative of current practices in many departments. The third quote illustrates the activities in innovative departments that are already implementing best practices suggested by research in collegiate mathematics education: sustained professional growth about teaching and learning. To highlight the challenges and benefits of spending time paying attention to teaching, we provide information from postsecondary and related secondary-level educational research of several types. This includes basic and applied educational research that identifies good instructional practices, examines experiences TAs bring with them to teaching, provides frameworks for the structuring of TA preparation, and gives insight into the kinds of mathematics-specific and teaching-specific knowledge that needs to be developed among TAs. And, once a program for supporting TAs to learn and grow as instructors is put in place, evaluation research explores the implementation of efforts to improve TAs’ teaching and the related impacts on undergraduate student learning. We close with promising practices and sketch anticipations for the future of the field of related research. Though not common thirty years ago, today most doctorateand master’s-granting institutions provide some kind of TA preparation for teaching [4a]. The content for this professional development often comes from mathematicians offering their collective wisdom from practical Jessica M. Deshler is assistant professor of mathematics at West Virginia University. Her email address is deshler@ math.wvu.edu.