Collegiate Football Athletes Research Articles

USE OF AN UPPER EXTREMITY FUNCTIONAL TESTING ALGORITHM TO DETERMINE RETURN TO PLAY READINESS IN COLLEGIATE FOOTBALL PLAYERS: A CASE SERIES.

Return to play decision making for upper extremity injuries is challenging due to a lack of evidence-based protocols and testing. Current guidelines utilize tests and measures with minimal evidence on re-injury risks and prediction. The purpose of this case series is to highlight a functional testing algorithm for upper extremities injuries and the outcomes for the patients that followed it. Case series. Six subjects (18 - 21 years old) who underwent shoulder capsulolabral repair secondary to recurrent instability and/or unyielding pain are included. All subjects underwent a criterion-based rehabilitation program before being assessed with the authors' upper extremity functional testing algorithm. The upper extremity functional testing algorithm consists of measures of active range of motion (AROM), passive range of motion (PROM), peak isometric force, a fatigue testing battery, and the closed kinetic chain upper extremity stability test (CKCUEST) to assess readiness for return to sport. All athletes achieved > 90% symmetry on at least two out of three tests during a fatigue testing protocol and at least 25 touches on the CKCUEST. All of the athletes returned to unrestricted football the season following surgical intervention. None of the athletes sustained an additional glenohumeral subluxation, dislocation, or upper extremity injury requiring surgical intervention for the remainder of their athletic careers (six years). The presented cases help to illustrate the effectiveness of the upper extremity functional testing algorithm to assess return to sport readiness for male collegiate football athletes. The algorithm included testing of AROM/PROM and strength that is typically used, but also included the CKCUEST and fatigue testing to further challenge and assess the upper extremity prior to returning to sports. 4.

On-Field Performance of an Instrumented Mouthguard for Detecting Head Impacts in American Football

Wearable sensors that accurately record head impacts experienced by athletes during play can enable a wide range of potential applications including equipment improvements, player education, and rule changes. One challenge for wearable systems is their ability to discriminate head impacts from recorded spurious signals. This study describes the development and evaluation of a head impact detection system consisting of a mouthguard sensor and machine learning model for distinguishing head impacts from spurious events in football games. Twenty-one collegiate football athletes participating in 11 games during the 2018 and 2019 seasons wore a custom-fit mouthguard instrumented with linear and angular accelerometers to collect kinematic data. Video was reviewed to classify sensor events, collected from instrumented players that sustained head impacts, as head impacts or spurious events. Data from 2018 games were used to train the ML model to classify head impacts using kinematic data features (127 head impacts; 305 non-head impacts). Performance of the mouthguard sensor and ML model were evaluated using an independent test dataset of 3 games from 2019 (58 head impacts; 74 non-head impacts). Based on the test dataset results, the mouthguard sensor alone detected 81.6% of video-confirmed head impacts while the ML classifier provided 98.3% precision and 100% recall, resulting in an overall head impact detection system that achieved 98.3% precision and 81.6% recall.

Longitudinal alteration of cortical thickness and volume in high-impact sports

Collegiate football athletes are subject to repeated head impacts. The purpose of this study was to determine whether this exposure can lead to changes in brain structure. This prospective cohort study was conducted with up to 4 years of follow-up on 63 football (high-impact) and 34 volleyball (control) male collegiate athletes with a total of 315 MRI scans (after exclusions: football n ​= ​50, volleyball n ​= ​24, total scans ​= ​273) using high-resolution structural imaging. Volumetric and cortical thickness estimates were derived using FreeSurfer 5.3’s longitudinal pipeline. A linear mixed-effects model assessed the effect of group (football vs. volleyball), time from baseline MRI, and the interaction between group and time. We confirmed an expected developmental decrement in cortical thickness and volume in our cohort (p ​< ​.001). Superimposed on this, total cortical gray matter volume (p ​= ​.03) and cortical thickness within the left hemisphere (p ​= ​.04) showed a group by time interaction, indicating less age-related volume reduction and thinning in football compared to volleyball athletes. At the regional level, sport by time interactions on thickness and volume were identified in the left orbitofrontal (p ​= ​.001), superior temporal (p ​= ​.001), and postcentral regions (p ​< ​.001). Additional cortical thickness interactions were found in the left temporal pole (p ​= ​.003) and cuneus (p ​= ​.005). At the regional level, we also found main effects of sport in football athletes characterized by reduced volume in the right hippocampus (p ​= ​.003), right superior parietal cortical gray (p ​< ​.001) and white matter (p ​< ​.001), and increased volume of the left pallidum (p ​= ​.002). Within football, cortical thickness was higher with greater years of prior play (left hemisphere p ​= ​.013, right hemisphere p ​= ​.005), and any history of concussion was associated with less cortical thinning (left hemisphere p ​= ​.010, right hemisphere p ​= ​.011). Additionally, both position-associated concussion risk (p ​= ​.002) and SCAT scores (p ​= ​.023) were associated with less of the expected volume decrement of deep gray structures. This prospective longitudinal study comparing football and volleyball athletes shows divergent age-related trajectories of cortical thinning, possibly reflecting an impact-related alteration of normal cortical development. This warrants future research into the underlying mechanisms of impacts to the head on cortical maturation.

Global and region-specific patient-reported outcomes pre and post a division I football season

ObjectiveDetermine the change in global and region-specific PROMs among athletes from one NCAA Division I football team during one season. DesignProspective cross-sectional study. SettingAthletic training facility. Patients or other participantsFifty-three Division I collegiate football athletes (n = 54) were eligible (20.1 ± 1.4 years, 187.7 ± 8.3 cm, and 113.5 ± 25.6 kg) for analyses. Participants completed five PROMs (Disablement in the Physically Active Scale [DPA], Epworth Sleep Score [ESS], Headache Impact Test [Hit-6], Disabilities of the Arm, Shoulder, and Hand [DASH], and the Lower Extremity Functional Scale [LEFS]) before the season and the same five PROMs after the season. Main outcome measuresA multivariate repeated measure analysis of variance (ANOVA) was conducted for all dependent variables. Alpha level was set at ɑ = 0.05. ResultsThe overall multivariate repeated measures ANOVA was significant for time (p = 0.01). Follow up one-way ANOVA’s indicated the DPA (p < 0.01, mean decrease/worse of 6.6 points) and LEFS (p = 0.01, mean decrease/worse of 4.1 points) were statistically significant between time points. ConclusionDivision I football can be detrimental to the physical, mental, and emotional health of the athletes. From these data, global and one region-specific PROM decreased over one season in one NCAA Division I football team.

Association between lower extremity movement compensations in the presence of PFPS among female collegiate football athletes: a cross sectional study

Association between lower extremity movement compensations in the presence of PFPS among female collegiate football athletes: a cross sectional study

Helmet Prototype Response Time Assessment using NCAA Division 1 Collegiate Football Athletes

Background: With advances in concussion research, an increasing amount of resources are being allocated to advancing football helmet technology. Objective: This study assesses the claim that a new modified helmet prototype provides greater field of view for the user as compared to a commonly worn helmet by players. Method: The helmets—Riddell SpeedFlex and the modified helmet—were compared based on user response time while performing a response test task using the FITLIGHT Trainer system, actual helmet field of view blockage, users’ subjective perception of field of view, and balance tests. Eighteen National Collegiate Athletic Association (NCAA) Division 1 American football student-athletes completed the response test task and questionnaire. Results: The results demonstrate evidence that the SpeedFlex helmet provided by the equipment staff significantly increases wearers’ response times, F(2,20) = 5.646, p &lt; 0.05. Also, while the quantification of the field of view perception was similar across helmet types, the student-athlete participants perceived the modified helmet to have significantly more field of view while performing the response test task, 1.56 v. 2.56; p &lt; 0.05 for frontal vision and 2.83 v. 5.39; p &lt; 0.05 for peripheral vision. Conclusion: In addition to the findings, this study also lays out a response time test protocol using the FITLIGHT Trainer system that can be used for assessment of response time testing of football and other helmets in future studies.

Epidemiology of Cervical Muscle Strains in Collegiate and High School Football Athletes, 2011-2012 Through 2013-2014 Academic Years.

Cervical muscle strains are an often-overlooked injury, with neck- and spine-related research typically focusing on spinal cord and vertebral injuries. To examine the rates and distributions of cervical muscle strains in collegiate and high school football athletes. Descriptive epidemiology study. Collegiate and high school football teams. The National Collegiate Athletic Association Injury Surveillance Program (NCAA-ISP) collected data from collegiate football athletes. The High School National Athletic Treatment, Injury and Outcomes Network (HS NATION) and High School Reporting Information Online (HS RIO) collected data from high school football athletes. Data from the 2011-2012 through 2013-2014 academic years were used. Athletic trainers collected injury and exposure data for football players. Injury counts, injury rates per 10 000 athlete-exposures (AEs), and injury rate ratios with 95% confidence intervals (CIs) were calculated. The NCAA-ISP reported 49 cervical muscle strains (rate = 0.96/10 000 AEs), of which 28 (57.1%) were TL (time loss; rate = 0.55/10 000 AEs). High School NATION reported 184 cervical muscle strains (rate = 1.66/10 000 AEs), of which 33 (17.9%) were TL injuries (rate = 0.30/10 000 AEs). The HS RIO, which collects only TL injuries, reported 120 TL cervical muscle strains (rate = 0.51/10 000 AEs). The overall injury rate was lower in the NCAA-ISP than in HS NATION (injury rate ratio = 0.58; 95% CI = 0.42, 0.79); when restricted to TL injuries, the overall injury rate was higher in the NCAA-ISP (injury rate ratio = 1.83; 95% CI = 1.11, 3.03). No differences were found when comparing TL injuries in HS RIO and the NCAA-ISP. Cervical muscle-strain rates were higher during competitions than during practices across all 3 surveillance systems for all injuries. Most cervical muscle strains were due to player contact (NCAA-ISP = 85.7%, HS NATION = 78.8%, HS RIO = 85.8%). The incidence of cervical muscle strains in football players was low compared with other injuries. Nonetheless, identifying and implementing interventions, particularly those aimed at reducing unsafe player contact, are essential to further decrease the risk of injury and associated adverse outcomes.

Performance Validity in Collegiate Football Athletes at Baseline Neurocognitive Testing.

To assess the prevalence of invalid performance on baseline neurocognitive testing using embedded measures within computerized tests and individually administered neuropsychological measures, and to examine the influence of incentive status and performance validity on neuropsychological test scores. Sport-related concussion management program at a regionally accredited university. A total of 83 collegiate football athletes completing their preseason baseline assessment within the University's concussion management program and a control group of 140 nonathlete students. Cross-sectional design based on differential incentive status: motivated to do poorly to return to play more quickly after sustaining a concussion (athletes) versus motivated to do well due to incentivizing performance (students). Immediate Post-Concussion and Cognitive Testing (ImPACT), performance validity tests, and measures of cognitive ability. Half of the athletes failed at least 1 embedded validity indicator within ImPACT (51.8%), and the traditional neuropsychological tests (49.4%), with large effects for performance validity on cognitive test scores (d: 0.62-1.35), incentive status (athletes vs students; d: 0.36-1.15), and the combination of both factors (d: 1.07-2.20) on measures of attention and processing speed. Invalid performance on baseline assessment is common (50%), consistent across instruments (ImPACT or neuropsychological tests) and settings (one-on-one or group administration), increases as a function of incentive status (risk ratios: 1.3-4.0) and results in gross underestimates of the athletes' true ability level, complicating the clinical interpretation of the postinjury evaluation and potentially leading to premature return to play.

Upper Extremity Morel-Lavallée Lesion in a Collegiate Football Player: A Case Report

A 20-year-old male collegiate football athlete reported a remarkably swollen elbow after direct contact with the ground. Initial radiographs and magnetic resonance imaging were negative for a fracture and soft tissue structural damage. After 2 weeks of conservative treatment, the athlete had no decrease in swelling and associated symptoms. He was diagnosed with a Morel-Lavallée lesion, later confirmed by diagnostic ultrasound imaging. The lesion was initially treated with compression therapy and cryotherapy to reduce swelling. Upon the final diagnosis the lesion was eventually incised, drained, and packed with iodoform sterile strips. It is hypothesized that many minor Morel-Lavallée cases are under- or misdiagnosed due to overlapping of signs and symptoms with other soft tissue traumas common in athletic populations. The procedures of this case can be utilized to optimize outcomes in future cases. While rare, Morel-Lavallée lesions can occur in athletic activities involving the upper extremity, and not solely crush injuries or traumatic and high-intensity accidents. This knowledge, along with the presented signs and symptoms, can give future healthcare professionals knowledge to include this diagnosis in their working differential diagnosis of injuries with similar presentations.

Longitudinal Changes in Hippocampal Subfield Volume Associated with Collegiate Football.

Collegiate football athletes are subject to repeated traumatic brain injuriesthat may cause brain injury. The hippocampus is composed of several distinct subfields with possible differential susceptibility to injury. The aim of this study is to determine whether there are longitudinal changes in hippocampal subfield volume in collegiate football. A prospective cohort study was conducted over a 5-year period tracking 63 football and 34 volleyball male collegiate athletes. Athletes underwent high-resolution structural magnetic resonance imaging, and automated segmentation provided hippocampal subfield volumes. At baseline, football (n = 59) athletes demonstrated a smaller subiculum volume than volleyball (n = 32) athletes (-67.77 mm3; p = 0.012). A regression analysis performed within football athletes similarly demonstrated a smaller subiculum volume among those at increased concussion risk based on athlete position (p = 0.001). For the longitudinal analysis, a linear mixed-effects model assessed the interaction between sport and time, revealing a significant decrease in cornu ammonis area 1 (CA1) volume in football (n = 36) athletes without an in-study concussion compared to volleyball (n = 23) athletes (volume difference per year = -35.22 mm3; p = 0.005). This decrease in CA1 volume over time was significant when football athletes were examined in isolation from volleyball athletes (p = 0.011). Thus, this prospective, longitudinal study showed a decrease in CA1 volume over time in football athletes, in addition to baseline differences that were identified in the downstream subiculum. Hippocampal changes may be important to study in high-contact sports.

Echocardiographic measurements of aortic root diameter (ARD) in collegiate football Athletes at pre-participation evaluation

BackgroundSome remodelling of the aortic root may be expected to occur with exercise but can already vary due to different body sizes, compositions and genetic predispositions. Attributing the cause of...

Collegiate Football Athlete Presents with Nontraditional Case of Rhabdomyolysis and Secondary Finding of Ureterocele

Collegiate Football Athlete Presents with Nontraditional Case of Rhabdomyolysis and Secondary Finding of Ureterocele

Echocardiographic measurements of left ventricular end-diastolic diameter and interventricular septal diameter in collegiate football athletes at preparticipation evaluation referenced to body surface area

BackgroundAre borderline echocardiogram structural measurements due to physiological adaptation or pathology in college football players? The normal reference data are very limited in this population. We report left ventricular end-diastolic...

Association of Serum 25-HydroxyvitaminD Concentrations With Glucose Profiles in Male Collegiate Football Athletes.

Low serum 25-hydroxyvitaminD [25(OH)D] concentrations are associated with a high risk of insulin resistance and Type 2 diabetes mellitus in adults. However, it is unknown whether this is the case for American collegiate football and rugby football athletes. This study investigated the associations between serum 25(OH)D concentrations and glucose profiles in male collegiate football athletes. Thirty-four collegiate athletes (13 American football players and 21 rugby football players) aged 21 years were recruited. Their body fat percent and visceral fat area were measured by dual-energy X-ray absorptiometry and magnetic resonance imaging, respectively. The participants completed an oral glucose tolerance test (75g glucose) with venous blood samples obtained at time points 0, 30, 60, 90, and 120min for the determination of plasma glucose and serum insulin concentrations. Fasting serum 25(OH)D concentrations were also measured. The prevalence of vitaminD deficiency and insufficiency was 17.6% and 58.8%, respectively. The serum 25(OH)D concentrations were negatively associated with the increments in the areas under the curve (iAUC) for glucose (r = -.429, p = .011) and were borderline significantly correlated with the Matsuda index (r = -.303, p = .082). No relationships were observed between the serum 25(OH)D concentrations and other glucose profiles. Multiple stepwise regression analysis of glucose iAUC concentrations as the dependent variable indicated that the serum 25(OH)D concentrations, but not body fat indicators, were independently associated with glucose iAUC (β = -0.390, p = .025). The serum 25(OH)D concentrations were only an independent predictor for glucose iAUC in male collegiate football athletes, suggesting that increased 25(OH)D concentrations would be helpful for maintaining glucose homeostasis.

Resting-state functional connectivity after concussion is associated with clinical recovery.

There has been a recent call for longitudinal imaging studies to better characterize the time course of physiological recovery following sport-related concussion (SRC) and its relationship with clinical recovery. To address this, we evaluated changes to resting-state functional connectivity (rs-FC) of the whole-brain network following SRC and explored associations between rs-FC and measures of clinical outcome. High school and collegiate football athletes were enrolled during preseason. Athletes that suffered SRC (N = 62) were assessed across the acute (within 48 hr) and sub-acute (days 8, 15, and 45) phases. Matched football athletes without concussion served as controls (N = 60) and participated in similar visits. Multi-band resting-state fMRI was used to assess whole-brain rs-FC at each visit using network-based statistic and average nodal strength from regions of interest defined using a common whole-brain parcellation. Concussed athletes had elevated symptoms, psychological distress, and oculomotor, balance, and memory deficits at 48 hr postconcussion relative to controls, with diminished yet significant elevations in symptoms and psychological distress at 8 days. Both rs-FC analyses showed that concussed athletes had a global increase in connectivity at 8 days postconcussion relative to controls, with no differences at the 48-hr, 15-day, or 45-day visits. Further analysis revealed the group effect at the 8-day visit was driven by the large minority of concussed athletes still symptomatic at their visit; asymptomatic concussed athletes did not differ from controls. Findings from this large-scale, prospective study suggest whole-brain rs-FC alterations following SRC are delayed in onset but associated with the presence of self-reported symptoms.

Effect of Concussions on Lower Extremity Injury Rates at a Division I Collegiate Football Program.

Background:Football has one of the highest injury rates (IRs) in sports, ranging from 4.1 to 8.6 per 1000 athlete-exposures (AEs). Previous research has reported that athletes may be at an increased risk of suffering lower extremity (LE) injuries after a concussion.Purpose/Hypothesis:The purpose of this study was to evaluate the rate of LE injuries in collegiate football athletes after a concussion. We predicted that the overall LE IR would increase after a concussion and that each position group would also demonstrate a similar increase in LE injuries after a concussion.Study Design:Cohort study; Level of evidence, 2.Methods:Daily attendance and injury records were prospectively collected by licensed team medical providers for the 2012 through 2016 college football regular seasons. Each injury report included the date of injury, position group, body part injured, and type of injury. IRs per 1000 AEs with 95% CIs were calculated to evaluate LE injuries at different time points after a concussion (remainder of season, next season, any additional seasons) and by months (<6 months, 6-12 months, >12 months). Mid-P exact tests were utilized to establish injury rate ratios (IRRs) to compare the IR between variables.Results:There was no significant difference in LE IRRs between the athletes post- versus preconcussion (P = .20) or between the postconcussion and no concussion (control) athletes (P = .08). There was an increased LE IR beyond 12 months in the postconcussion group (IR, 9.08 [95% CI, 3.68-18.89]) compared with the no concussion group (IR, 2.88 [95% CI, 2.04-3.96]) (IRR, 3.16 [95% CI, 1.21-7.15]; P = .02). Line position players had an increase in LE injuries after a concussion (IRR, 6.22 [95% CI, 1.31-23.68]; P = .03) compared with linemen with no concussion.Conclusion:There was no initial increase in LE IRs immediately after a concussion; however, there was an increased LE IR more than 12 months after a concussion. There was no increase in LE IRs demonstrated by skill and other position groups. Line position players experienced an increased LE IR the next season after a concussion or greater than 12 months after the injury.

Serum 25-Hydroxyvitamin D Concentrations Are Inversely Correlated with Hepatic Lipid Content in Male Collegiate Football Athletes

Lower serum 25-hydroxyvitamin D (25(OH)D) concentrations are associated with more weight and fat mass gain in adults in the general population, but it is unknown whether this is the case in collegiate football athletes with greater body weight. This study aimed to investigate associations of serum 25(OH)D concentrations with body fat and ectopic fat accumulation, and to determine which fat indicators are closely related to serum 25(OH)D in male collegiate football athletes. Thirty-four collegiate athletes aged 21 years were recruited. Serum 25(OH)D concentrations and the levels of visceral fat area (VFA), vastus lateralis intramyocellular lipid (IMCL), extramyocellular lipid (EMCL), and intrahepatic lipid (IHCL) were measured. Serum 25(OH)D concentrations were negatively associated with the IHCL values (r = −0.372, p = 0.030), and the relationship remained after adjustment for several factors (r = −0.378, p = 0.047). Additionally, multiple stepwise regression analysis of IHCL content as the dependent variable indicated that 25(OH)D concentrations were a stronger predictor of IHCL content (β = −0.363, p = 0.030) than % body fat and VO2peakFFM. Higher serum 25(OH)D concentrations are more closely related to lower IHCL content rather than any other fat indicators, suggesting that increasing serum 25(OH)D concentrations may have some effect that inhibits lipid accumulation in hepatic tissue, especially in heavy athletes.

Predicting Concussion Incidence from Baseline Data in High School and Collegiate Football Athletes

Predicting Concussion Incidence from Baseline Data in High School and Collegiate Football Athletes

Omega-3 Index in Division I Collegiate American FootballAthletes

American football athletes are exposed to repetitive head impacts (RHI) that, even in the absence of a clinically discernible head injury, result in quantifiable neurological damage. Pre-clinical studies utilizing rodent models indicate that traumatic brain injuries (TBI) can cause a reduction in neuronal omega-3 fatty acids (n-3FAs), specifically docosahexaenoic acid (DHA). Pre-injury administration of n-3FAs, however, has shown to effectively allay the pathological response to TBI. Furthermore, one study has demonstrated the potential neuroprotective effect of DHA supplementation in American football athletes evidenced by a marked reduction in blood biomarkers of axonal injury. Given that the American diet is scarce in the n-3FAs DHA and eicosapentaenoic acid (EPA), the potential neuroprotective effect of n-3FA supplementation may uniquely benefit American football athletes. PURPOSE: This descriptive study sought to examine the omega-3 index, an indicator of n-3FA status, in American collegiate football athletes not supplementing with n-3FAs. METHODS: One hundred twelve (n = 112) athletes participated in this study. Blood was obtained via finger stick and collected on blood spot cards pre-treated with an antioxidant cocktail. The dried blood samples were analyzed by gas chromatography for fatty acid (FA) levels (expressed as a % of total blood FAs). A regression formula (r = 0.98) was used to estimate the percentage of DHA and EPA in red blood cell phospholipids (omega-3 index). RESULTS: Levels of DHA, EPA, and alpha-linolenic acid (ALA) were (mean ± SD) 2.27% ± 0.01% (range = 1.1% - 5.2%), 0.39% ± 0.00% (range = 0.2% - 1.2%) and 0.39% ± 0.00% (range = 0.1% - 1.0%), respectively. Mean omega-6 levels were 9.55 ± 1.72 (range = 4.5 - 13.9) times higher than n-3FAs levels. The mean omega-3 index was 4.35% ± 0.01% (range = 2.8% - 8.0%). Sub-optimal n-3FA levels (i.e., an index < 8.0%) were observed in 99.12% of participants. CONCLUSION: These data suggest that dietary intake of the n-3FAs DHA and EPA may not be adequate in American collegiate football athletes. Though the current evidence relates n-3FA deficiency to an increased risk for cardiovascular risk, American football athletes may derive neuroprotective benefit from n-3FA supplementation with little to no risk.

Total and Segmental Body Composition Examination in Collegiate Football Players Using Multifrequency Bioelectrical Impedance Analysis and Dual X-ray Absorptiometry.

Raymond, CJ, Dengel, DR, and Bosch, TA. Total and segmental body composition examination in collegiate football players using multifrequency bioelectrical impedance analysis and dual X-ray absorptiometry. J Strength Cond Res 32(3): 772-782, 2018-The current study examined the influence of player position on the agreement between multifrequency bioelectrical impedance analysis (MfBIA) and dual X-ray absorptiometry (DXA) when assessing total and segmental percent body fat (BF%), fat mass (FM), and fat-free mass (FFM) in National Collegiate Athletic Association Division I collegiate football athletes. Forty-four male collegiate athletes (age = 19 ± 1 year; height = 1.9 ± 1.0 m; and body mass = 106.4 ± 18.8 kg) participated. Player positions included: offensive linemen (OL; n = 7), tight ends (TE; n = 4), wide receivers (WR; n = 9), defensive linemen (DL; n = 6), defensive backs (DB; n = 8), linebackers (LB; n = 6), and running backs (RB; n = 4). Total and segmental body composition measured using MfBIA were compared with values obtained using DXA. Compared with DXA, MfBIA underestimated BF% (3.0 ± 3.8%), total FM (2.5 ± 4.3 kg), arm FM (0.4 ± 0.8 kg), arm FFM (1.4 ± 0.9 kg), leg FM (2.8 ± 2.0 kg), and leg FFM (5.4 ± 2.4 kg) (all p < 0.001; arm FM p = 0.002) and overestimated total FFM (-2.4 ± 4.5 kg) (p < 0.001). Limits of agreement (LOAs) were: ±7.39% (BF%), ±8.50 kg (total FM), ±1.50 kg (arm FM), ±1.83 kg (arm FFM), ±3.83 kg (leg FM), ±4.62 kg (leg FFM), and ±8.83 kg (total FFM). No significant differences were observed between devices for trunk FM (-0.3 ± 3.0 kg; p = 0.565) and trunk FFM (0.4 ± 2.4 kg; p = 0.278), with LOAs of ±5.92 and ±4.69 kg, respectively. Player position significantly affected all between-device mean body composition measurement differences (adjusted p ≤ 0.05), with OL demonstrating the greatest effect on each variable. Therefore, MfBIA does not seem accurate in examining between-player body composition in college football players.