College English education in TCM universities should set up its own unique education system characterized by the TCM characteristics, manipulability and generalizability. Here the Beijing University of Chinese Medicine was taken as an example to discuss the necessity, theoretical basis, specific methods and preliminary achievements of the application ability-oriented college English education reform in the past six years that serves students’ learning needs and career development as well as the university’s talents cultivation. Key words: Traditional Chinese medicine and pharmacy; Eductional reform; College English; Application ability