The upgrading strategy of professional towns is an important guarantee for the transformation of the economic development mode. At present, the economic development of Guangdong Province of China is facing a new situation of changing modes, adjusting structures, and changing forces [1]. How to speed up the transformation and upgrading of professional towns and promote economic development in the township, and thus promote the rapid economic development of Guangdong Province of China, is a serious challenge. The study finds that although the collaborative innovation development of professional towns in Guangdong Province of China is effective, there are still many problems and deficiencies: 1) low level of collaborative innovation; 2) narrow scope of collaborative innovation; 3) single structure of collaborative innovation; 4) a low dimension of collaborative innovation. This research is based on the new era of the “Internet+” development and takes the lead in collaborative innovation research based on the perspective of the development of the town-region economy, and proposes innovative research results for the collaborative innovation of professional towns and professionalism for Guangdong Province of China [2]. Based on this, this research is mainly based on the summary of the current situation and problems in the development of professional townships, and builds the “Six Major Systems Collaborative Practice” from the six dimensions of management factors, enterprises, industries, platforms, and “government, industry, research and application”. The new models what the town has is about innovation and development.
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